Antidandruff Activity of Extracts From Kaffir Lime (Citrus Hystrix Dc.) Prepared By Different Solvents

Abstract

Pytiriasiscapitis or dandruff is a condition of exofoliate peeling of the stratum corneum layer in the scalp. There are some factors that suspected to caused dandruff such as increased production of sebum, sensitivity individual against the sebum and microbiota activity in scalp, i.eMalasseziafurfur, Malassezia globosa, Pytirosporumovale, and Candida albicans. Therefore, treatment of dandruff is aimed to reduced sebum on the scalp and inhibit the growth of yeast population that causes dandruff. The juice of kaffir lime fruit (Citrus hystrix DC.) has been used by Indonesian people for tradisional therapy of dandruff. This study thas been conducted to find out antidandruff activities of M. furfur from kaffir lime fruit juice, peel, and leaves of kaffir lime tree extracted by ethanol, ethyl acetat, and n-hexan solvents. Antifungal activitiesis measured by inhibition zones using well diffusion agar methods.All citrus extracts showed antifungal activities against M. furfur with ethyl acetat solvent indicated the highest antidandruff activities, then followed by n-hexan, and ethanolicsolvent; although ethyl acetat and n-hexan was not significantly different (p>0.05).Leaves extract showed highest inhibition activities, then followed by fruit juice and peel extract, although leaves and fruit juice extracts was not significantly different (p>0.05).Part of the plant citrus consist of a alkaloid, saponin, tannin, phenolic, flavonoid, terpenoid, glikosida, and steroid. Antifungal activities suspected of phenolic, flavonoid, and terpenoid compounds. These results suggested that kaffir lime are effective against dandruff microbial and has potential as a herbal shampoo for dandruff treatment. AKTIVITAS ANTIKETOMBE EKSTRAK JERUK PURUTMENGGUNAKAN BEBERAPA JENIS PELARUT ABSTRAK Pytiriasiscapitisatau lebih dikenal sebagai ketombe, merupakan suatu kondisi eksfoliasi atau pengupasan berlebih pada lapisan stratum korneum di kulit kepala.Beberapa faktor yang diduga memacu timbulnya ketombe, antara lain: peningkatan produksi sebum, sensitivitas individu terhadap sebum dan aktivitas mikrobiota kulit kepala, sepertiMalassezia furfur, M. globosa.,Pytirosporumovale dan Candida albicans.Karena itu, pengobatan ketombe ditujukan untuk mengurangi sebum pada kulit kepala dan menghambat pertumbuhan populasi khamir penyebab ketombe.Air perasan buah jeruk purut (Citrus hystrixDC.) telah digunakan secara tradisional untuk mengatasi ketombe. Telah dilakukan penelitian untuk mengetahui aktivitas antifungi penyebab ketombe M. furfurmenggunakan metode difusi agar terhadap ekstrak air perasan buah, kulit buah dan daun jeruk purut dengan pelarut etanol, etil asetat, dan n-heksan.Seluruh ekstrak; ekstrak etanol, etil asetat, dan n-heksan dari air perasan buah, kulit buah, dan daun jeruk purut memiliki aktivitas penghambatan terhadap jamur penyebab ketombe M. furfur.Seluruh ekstrak jeruk purut mampu menghambat pertumbuhan M. furfur.Ekstrak etil asetat memberikan aktivitas penghambatan tertinggi, kemudian ekstrak n-heksan dan etanol; walaupun penghambatan ol...

Formulation of Lozenges Containing Menthol and <i>Citrus hystrix</i> DC. Essential Oil for Pharyngitis Support Treatment

“…The objective was to identify the lowest ratio that effectively masked the bitter taste while preserving the desired characteristics of the lozenges. 16 The value of Fm was 16,17 which is more than F = 3.68 (p=0.00018) (Table 8). The results were similar to the aroma taste assessment in which the bitterness scores of all formulas were significantly different from each other.…”

“…11 Furthermore, this plant is also used as a natural insecticide (botanical insecticide), [12][13] an essential ingredient in aromatherapy, [14][15] and also as an antidandruff. 16 The antimicrobial activities observed in Citrus hystrix DC can be attributed to the presence of essential oils found in various parts of the plant, including the leaves, fruits, and seeds. However, it is worth noting that the majority of essential oil production is typically derived from the fruit of Citrus hystrix.…”

Aktivitas Antibakteri Air Perasan Jeruk Purut (Citrus hystrix DC.) terhadap Bakteri Salmonella thypi secara In Vitro

“…Salah satu tanaman jeruk yang banyak dimanfaatkan oleh masyarakat Kalimantan Timur adalah jeruk purut (Citrus hystrix DC.). Berbagai penelitian mengenai manfaat jeruk purut menunjukkan efektivitas jeruk purut sebagai antioksidan [2], kardioprotektif, hepatoprotektif [3], anti kanker pankreas [4], antiketombe [5] dan antibakteri [6] [7]. Kemampuan antibakteri ini telah dilakukan terhadap bakteri Acinetobacter baumannii [7] Staphylococcus aureus, Escherichia coli [6] [2], Klebsiella pneumoniae [8], Shigella spp., Salmonella arizonae, Serratia spp., Morganella morganii, Citrobacter spp., Plesiomonas shigelloides, Providencia spp., Yersinia enterocolitica dan Enterobacter spp [9].…”