2022
DOI: 10.7324/japs.2021.120103
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Antidiabetic activity of Coccinia grandis (L.) Voigt: Bioactive constituents, mechanisms of action, and synergistic effects

Abstract: Diabetes mellitus is a disease caused by irregular carbohydrate metabolism in association with an inadequate insulin level and insulin resistance. As synthetic drugs generate undesired side effects, the treatment of diabetes using natural medicines, especially medicinal plants, has become a potential alternative therapy. Medicinal plants contain many secondary metabolites and play a crucial role in diabetes mellitus therapy. For many years, Coccinia grandis L. Voigt (family: Cucurbitaceae) has been widely util… Show more

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