Antidiabetic activity of <i>musa acuminata</i> colla fruit peel (MACFP) ethanol extract in glucose-induced diabetic rats

Genatrika, Erza; Laksari, Visda Nila Happy; Tjiptasurasa, Tjiptasurasa

doi:10.1051/matecconf/201819707007

Cited by 4 publications

(3 citation statements)

References 3 publications

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“…This result similar to research by Genatrika et al, which provided that ethanol peel extract of Musa acuminata Colla with dose of 500 mg/kg bw could reduce blood glucose level 42.62%, 375 mg/kg bw 37.26% and 250 mg/kg bw 24.12% [23]. Research by Jannat et al expressed that ripe fruit peels of M. seminifera Lour with a dose of 50 mg/kg bw could reduce blood glucose level 16.5%, 100 mg/kg bw 25.2%, 200 mg/kg bw 29.8% and 400 mg/kg bw 35.1% [24].…”

Section: Resultssupporting

confidence: 91%

Comparison of Antihyperglycemic Activity of Different Parts of Klutuk Banana (Musa Balbisiana Colla)

2021

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Objective: Banana is a plant that grows in Indonesia and is widely consumed by Indonesian people. One of banana type is klutuk banana (Musa balbisiana Colla). There were many types of researches about klutuk banana for antidiabetic activity; however, antidiabetic activity of its peel and pulp are still unknown. Methods: The objective of the study was to determine of antihyperglycemic activity of different parts of klutuk banana. Animals were divided into 15 groups, namely normal control, negative control, positive control (glibenclamide 0.65 mg/kg body weight (bw), and 12 sample groups. All animals were given 2 g/kg bw glucose monohydrate and blood glucose level was measured every 30 min for 120 min. Results: The results of the oral glucose tolerance test (OGTT) showed that KPE2 (klutuk peel extract 350 mg/kg bw) gave higher activity to decrease blood glucose level compared to the other groups at the minute of 30 (-24.83%; p. 0.00), 60 (-33.93%; p. 0.000), 90 (-46.29%; p. 0.000) and 120 (-35.44%; p. 0.000). Conclusion: The klutuk peel extract has very strong antioxidant activity and antihyperglycemic activity at a dose of 350 mg/kg bw.

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Section: Resultssupporting

confidence: 91%

Comparison of Antihyperglycemic Activity of Different Parts of Klutuk Banana (Musa Balbisiana Colla)

2021

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“…To our knowledge this is the first description of the ability of methanol extract of M. acuminata fruit peels to reduce blood glucose. The hypoglycemic activity of ethanolic extract of M. acuminata fruit peels have been reported for glucose-induced diabetic rats [33] . The antioxidant and antihyperglycemic (alpha-amylase and alpha-glucosidase inhibitory properties) of M. sapientum (Latundan banana), M. acuminata (Cavendish banana) and M. acuminata (Red Dacca banana) have also been reported [34] .…”

Section: Resultsmentioning

confidence: 99%

Glucose lowering effect of wild banana cultivar of <em>Musa acuminata </em>L. fruit peels from Bandarban, Bangladesh in Swiss albino mice

Azad¹,

Jahan²,

Rahmatullah³

2022

J. Med. Plants Stud.

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Diabetes is a debilitating disease, which has become a serious concern in Bangladesh. Earlier studies have shown that extracts of fruit skins of various cultivars of banana species can improve glucose tolerance in glucose-loaded mice. The objective of this study was to evaluate through oral glucose tolerance test (OGTT) of methanol extract of fruit peels of a wild cultivar of Musa acuminata, which can be found in southeast Bangladesh forests. In OGTT, ripe fruit skin methanolic extract of Musa acuminata (MEMA) showed a reduction by 0.04, 19.65, 19.80 and 26.84%, when administered per kg body weight in mice at doses of 50, 100, 200 and 400 mg, respectively. A standard glucose lowering drug, glibenclamide decreased blood glucose levels by 21.08 and 37.38% at doses of 2 and 10 mg. Overall, the findings indicate that MEMA can improve glucose tolerance and may be of potential use to diabetic patients.

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“…Penelitian yang dilakukan [21] melaporkan ekstrak etanol 96% kulit pisang cavendish pada dosis 250 mg/kgBB sudah dapat menurunkan kadar glukosa dalam darah dengan metode uji toleransi gula oral. Glibenklamid 0,6 mg/kgBB digunakan sebagai kontrol positif mampu menurunkan kadar glukosa dalam darah sebesar 45,83%.…”

Section: Antihiperglikemiaunclassified

Penelusuran Pustaka Kandungan Senyawa dari Ekstrak Kulit Pisang Raja (Musa paradisiaca var raja) dan Kulit Pisang Cavendish (Musa cavendishii) dalam Beberapa Aktivitas Farmakologi

Safari

Patricia

Syafnir

2022

BCSP

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Abstract. Plantain (Musa paradisiaca var raja) and cavendish banana (Musa cavendishii) is a plant that has long been used by the public as a medicinal plant. The parts of the banana plant are known to have pharmacological activity, while the banana peel is only considered waste that is thrown away after the fruit is taken. The research method used is a Systematic Literature Review with literature searches related to the pharmacological activity of the extracts of raja banana peel and cavendish banana peel. The data obtained is then displayed in tabular form and explained in paragraph form. The results showed that the extracts of plantain peel and cavendish banana peel had pharmacological activities such as antibacterial, antihyperglycemic and antioxidant. which is thought to come from the content of a class of compounds in plantain peels and cavendish banana peels such as alkaloids, phenols, flavonoids, tannins and saponins. Abstrak. Pisang raja (Musa paradisiaca var raja) dan pisang cavendish (Musa cavendishii) merupakan tanaman yang sejak dahulu sudah digunakan oleh masyarakat sebagai tanaman obat. bagian-bagian dari tanaman pisang sudah diketahui memiliki aktivitas farmakologis, sedangkan kulit pisang hanya dianggap limbah yang dibuang setelah diambil buahnya. Tujuan dari penelusuran pustaka ini adalah untuk mengetahui aktifitas farmakologi dari kandungan golongan senyawa ekstrak kulit pisang raja (Musa paradisiaca var. Raja) dan kulit pisang cavendish (Musa cavendishii). Metode penelitian yang digunakan adalah Systematic Literature Review dengan penelusuran pustaka terkait aktivitas farmakologi dari ekstrak kulit pisang raja dan kulit pisang cavendish. Data yang diperoleh kemudian ditampilkan dalam bentuk tabel dan dijelaskan dalam bentuk paragrafh. Hasil yang didapat menunjukan bahwa ekstrak kulit pisang raja dan kulit pisang cavendish memiliki aktivitas farmakologis seperti antibakteri, antihiperglikemia dan antioksidan yang diduga berasal dari kandungan golongan senyawa pada kulit pisang raja dan kulit pisang cavendish seperti alkaloid, fenol, flavonoid, tannin dan saponin.

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Antidiabetic activity of musa acuminata colla fruit peel (MACFP) ethanol extract in glucose-induced diabetic rats

Cited by 4 publications

References 3 publications

Comparison of Antihyperglycemic Activity of Different Parts of Klutuk Banana (Musa Balbisiana Colla)

Comparison of Antihyperglycemic Activity of Different Parts of Klutuk Banana (Musa Balbisiana Colla)

Glucose lowering effect of wild banana cultivar of <em>Musa acuminata </em>L. fruit peels from Bandarban, Bangladesh in Swiss albino mice

Penelusuran Pustaka Kandungan Senyawa dari Ekstrak Kulit Pisang Raja (Musa paradisiaca var raja) dan Kulit Pisang Cavendish (Musa cavendishii) dalam Beberapa Aktivitas Farmakologi

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