Antifungal activities of Terminalia ivorensis A. Chev. bark extracts against Candida albicans and Aspergillus fumigatus.

Ouattara, Sié; Elisée, Kporou Kouassi; Joseph, Djaman Allico

doi:10.5455/jice.20121205083931

Cited by 10 publications

(5 citation statements)

References 13 publications

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“…The most active extracts found in Ivory coast (hexane extracts of Terminalia mantaly with a MFC = 0.024 mg/mL and the hydroethanolic extract of Terminalia ivorensis with a MFC of 0.097 mg/mL) have an activity similar to that of Ketoconazole. 16 This confirms the attention in the search for new antifungal molecules. Medicinal plants have many virtues and must be sufficiently explored to effectively fight against vaginitis.…”

Section: Discussionsupporting

confidence: 57%

“…The most active extracts are found in Ivory Coast with respectively the hexane extracts of Terminalia mantaly with MFC = 0.024 mg/ mL 15 and the hydroethanolic extract of Terminalia ivorensis with an MFC of 0.097 mg/ mL. 16 A few active molecules have nevertheless been isolated from the West African medicinal plants with antifungal activity studied. 17 This table indicates West Africa medicinal plants with antifungal activity Table 3.…”

Section: Resultsmentioning

confidence: 99%

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Antifungal activity of African medicinal plants: a review

MES

et al. 2023

OAJS

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In Africa many plants are used as antifungals. However, journals analysing the work of antifungal activities of plants in West Africa in recent years are rare. This study is a synthesis of publications from 2006 to 2021 on plants traditionally used in the fight against antifungal diseases. A systematic search was carried out in the Pub Med and Google Scholar database using the following keywords: vaginitis; West Africa; antifungal activity; medicinal plants; plant extracts; for articles published from 2006 to 2021. These selected articles focus on ethnobotanical studies, in vitro antifungal tests and molecules isolated from these plants. A total of 46 papers were selected from 7 West African countries with 56 plants studied. Nigeria and Ivory coast did more work with 22 and 14 papers respectively and studied more plants with 23 and 17 respectively. 43% of plants show good activity in vitro on strains of Candida albicans in the laboratory with a minimum fungicide concentration and a percentage of inhibition above 50%. The most active extracts are found in Ivory coast with respectively the hexane extracts of Terminalia mantaly with a minimum fungicide concentration= 0.024 mg / mL and the hydroethanolic extract of Terminalia ivorensis with a minimum fungicide concentration of 0.097 mg / mL. It is clear that the traditional West African pharmacopoeia can make an important contribution for the management of vaginitis.

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Section: Discussionsupporting

confidence: 57%

Section: Resultsmentioning

confidence: 99%

Antifungal activity of African medicinal plants: a review

MES

et al. 2023

OAJS

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“…The NMR data was consistent with 23-hydroxy tormentic acid-28-O-D-glucopyranoside,(2α,3β,19α,23-tetrahydroxyurs-12-en-28-oic acid-28-O-D-glucopyranoside (niga-ichigoside Fl) [19][20] . Fractionation of ethyl acetate fraction afforded luteolin (6), apigenin (7), gallic acid (8) and methyl gallate (9).…”

Section: Resultsmentioning

confidence: 99%

“…Terças et al ( 2017) 6 reported the antifungal potential of T. catappa extracts against C. albicans and detected tannins and flavonoid glycoside in the most active subfraction. In addition, Sitapha et al, (2013) 7 concluded that extracts from bark of T. ivorensis A. Chev. exhibited antifungal activity against A. fumigatus more than against C. albicans.…”

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Terminalia arjuna flowers: Secondary metabolites and antifungal activity

Elwekeel¹,

Amin²,

Khairallah³

et al. 2022

Pharm Sci Asia

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The current increased incidence of fungal infections could be attributed to the increased number of immunocompromised patients who usually suffer from fungal infection. Accordingly, the development of antifungal agents with wide spectrum of activity or new mechanism of action is a crucial need. Yeasts such as Candida sp., filamentous fungi such as; Aspergillus sp., Fusarium sp. and Rhizopus sp., as well as the dermatophytes Trycophyton sp., Microsporum sp. and Epidermophyton sp. are considered as the most frequent fungal pathogens. Among all invasive fungal infections, Candida represents 70-90% while Aspergillus represents 10-20% 1 . In immunosuppressed patients receiving chronic corticosteroid treatment, A. fumigatus is responsible for over 70% of all cases of invasive pulmonary aspergillosis. Recently, pulmonary aspergillosis was also noted as a secondary complication of coronavirus disease 2019 (COVID-19), especially among critically ill patients in the intensive care unit (ICU) 2 .Candidiasis is the infection with overgrowth of Candida species, especially C. albicans, in the mucous membranes such as oral cavity and vagina 3 . Oral candidiasis occurs in children, patient on antibiotic or steroid therapy, or immunodeficient patients, while in women Candida infection causes vaginitis, white vaginal discharge and itching 3 .Plant kingdom offers a wide diversity of species with different enzyme systems and biochemical patterns. This provides a wide and undepletable source of chemical chemical moieties with variable biological activities. Testing the antifungal activity of plant extracts, using

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“…Many plants are used in the African pharmacopoeia to treat several fungal diseases. This is the case of Terminalia ivorensis A. CHEV which is a plant of the ivorian medicinal flora whose studies conducted by [14] revealed the antifungal activities of this plant.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Hydroalcoholic Extract of Terminalia ivorensis on Feet Fungus Disease

Ouattara

Marcelin

Elisée

et al. 2023

EJMP

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Despite the evolution of modern medicine, traditional medicine remains widespread in developing countries and its use continues to increase in industrialized countries.It is the same way that the effectiveness of the hydroalcoholic extract of Terminalia ivorensis was tested on the feet fungus disease of volunteers. Objective: The present work is oriented in the preparation of an antimicrobial hydroalcoholic extract of Terminalia ivorensis, a medicinal plant in order to enhance it. Materials and Methods: One hundred (100) grams of powder from trunk bark’s Terminalia ivorensis were extracted by homogenisation in a solvent mixture of 70% ethanol and 30% distilled water in a blender. After six grinding cycles, the homogenate obtained in each case was first wrung out in a clean white cloth square and then successively filtered twice on cotton wool and on Whatman 3 mm filter paper. The filtrate obtained was dried in a Venticell oven. The powder obtained constitutes the hydroalcoholic extract (or The 70% hydroethanolic extract). The 70% hydroethanolic extract of Terminalia ivorensis obtained was mixed with water to obtain a pasty liquid form before being tested on feet fungus disease using a cotton ball. Results: The extract had activity on these different shapes of feet fungus disease with a marked improvement. The volunteers who finished their treatment have been cured of feet fungus disease. Conclusion: The treatment results obtained revealed that the hydroalcoholic extract has good antimicrobial activity. The hydroalcoholic extract can be an undeniable source for the development of Improved Traditional Medicines (ITM) against feet fungus disease.

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Antifungal activities of Terminalia ivorensis A. Chev. bark extracts against Candida albicans and Aspergillus fumigatus.

Cited by 10 publications

References 13 publications

Antifungal activity of African medicinal plants: a review

Antifungal activity of African medicinal plants: a review

Terminalia arjuna flowers: Secondary metabolites and antifungal activity

Effectiveness of Hydroalcoholic Extract of Terminalia ivorensis on Feet Fungus Disease

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