Antimicrobial activities of crude leaf extracts of Acalypha wilkesiana

Alade, P. I.; Irobi, O.N.

doi:10.1016/0378-8741(93)90033-2

Cited by 163 publications

(106 citation statements)

References 2 publications

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“…The effect of the methanol extract on the bacterial population of S. lutea was bacteriostatic in all concentrations tested; nevertheless, a bactericidal effect was observed on the bacterial population of V. cholerae Tor (MBC at 4 h; MIC at 6 h). In other species of the genus Acalypha (A. guatemalensis, A. wilkesiana, A. torta, A. siamensis and A. indica), it has been observed that extracts of high polarity showed antibacterial activity (Alade and Irobi, 1993;Caceres et al, 1993Caceres et al, , 1998Perumal et al, 1999;Wiart et al, 2004).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the antimicrobial activity of Acalypha monostachya Cav. (Euphorbiales: Euphorbiaceae)

Canales¹

2011

Afr. J. Pharm. Pharmacol.

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Acalypha monostachya (Euphorbiaceae) is used by the inhabitants of San Rafael and ZapotitlanSalinas, Puebla, Mexico, to alleviate illnesses of bacterial and fungal origin. We analyzed the antimicrobial activity of A. monostachya and some of its chemical features. The extracts were obtained by percolation. The antibacterial and antifungal activities were examined through the disc-diffusion method. The general toxicity was carried out by using Artemia salina. The quenching of free radicals by extracts was evaluated by the decolouration of a methanol solution of DPPH·. Total phenols were determined by Folin Ciocalteu reagent. Gram-positive and negative bacteria were sensitive to methanol and hexane extracts. The methanol extract had a bactericidal effect on Vibrio cholera Tor (MIC = 1000 µg/mL). The fungi strain most sensitive to this extract was T. mentagrophytes (LC 50 = 430 µg/mL). The methanol extract showed inhibition of DPPH· radical (SC 50 = 3.45 µg/ml), 43.4% of total phenolics and was toxic against A. salina (LC 50 = 4.5 µg/mL). The methanol extract showed a variety of phenolic compounds, while hexane extract showed different fatty acids methyl ester. The bacterial, antifungal, antioxidant activities and a qualitative chemical characterization of A. monostachya's extracts are reported here for the first time.

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Section: Discussionmentioning

confidence: 99%

Evaluation of the antimicrobial activity of Acalypha monostachya Cav. (Euphorbiales: Euphorbiaceae)

Canales¹

2011

Afr. J. Pharm. Pharmacol.

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“…A control well containing Gentamicin (5 µg/ml) was placed in each of the plates seeded with bacteria. The Petri plates were then incubated at 37°C for 24 h (Alade and Irobi, 1993;Igbinosa et al, 2009). Antibacterial activity was expressed as average diameter of the zones of inhibition calculated as a difference in diameter of the observed zones and those of the wells.…”

Section: Antibacterial Testmentioning

confidence: 99%

Antibacterial constituents of the leaves of Dacryodes edulis

Ajibesin¹,

Essien²,

Adesanya³

2011

Afr. J. Pharm. Pharmacol.

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Dacryodes edulis is a dioecious, small to medium-sized tree, reaching 20 to 25 m high. Different parts of the plant are used to treat many diseases including skin infections, digestive tract disorder and dysentery. The leaves were macerated in 50% ethanol and the liquid extract concentrated to dryness. The dry extract was evaluated for antibacterial activity by using agar diffusion method. The extract was partitioned between water, ethyl acetate and butanol successively and further subjected to antibacterial testing. The most active fraction, ethyl acetate fraction, was purified through various chromatographic methods to obtain pure compounds identified by spectroscopic methods as ethylgallate and quercitrin. These compounds gave good antibacterial effects, while the minimum inhibitory concentrations of the fractions and the pure compounds ranged between 12.5 and 250 µg/ml. These phenolic compounds are reported for the first time in this plant.

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“…Several experimental approaches are used. Usually water is used for extraction just as is used traditionally [18] . Other solvents used for extraction apart from water include chloroform, petroleum ether, ethanol, methanol, acetone etc.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activities of Chrysophyllum Albidum Leaves, Fruits and Seeds

George¹,

Adenipekun²,

Fasogbon³

et al. 2018

Am. J. Biomed. Sci.

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Background: Chrysophyllum albidum is a medicinal plant that belongs to the Sapotaceae family. This study was carried out to determine the antimicrobial activities of the leaves, seeds and fruits of Chrysophyllum albidum.Materials and Methods: The fruits, leaves and seeds of Chrysophyllum albidum were extracted with distilled water, Seaman's Schnapps, Methanol and Petroleum ether using cold extraction. These extracts were tested on various organisms. Antimicrobial activities of the various extracts were determined using the agar well diffusion technique to detect the Minimum Inhibitory Concentration (MIC).Results and Discussion: Methicillin Resistant Staphylococcus aureus was inhibited by all the extracts at MIC between 32µg/ml to 512µg/ml except Seaman's Schnapps leaves and petroleum ether seed extract. The fruit extracts had a high antimicrobial activity against all the tested organisms. The extracts from Seaman's Schnapps had little activity while the aqueous extracts had MIC ranging from 64-512µg/ml on most of the organisms tested. The statistical analysis of the extracts indicated P-value of 0.122 for Aqueous extracts, which was statistically insignificant compared to 0.003 for Methanolic extracts and 0.001 for Seaman's Schnapps extracts in the inhibition pattern of the extracts. Aqueous extracts showed more inhibitory activity than Methanolic and Seaman's Schnaps extracts.

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Antimicrobial activities of crude leaf extracts of Acalypha wilkesiana

Cited by 163 publications

References 2 publications

Evaluation of the antimicrobial activity of Acalypha monostachya Cav. (Euphorbiales: Euphorbiaceae)

Evaluation of the antimicrobial activity of Acalypha monostachya Cav. (Euphorbiales: Euphorbiaceae)

Antibacterial constituents of the leaves of Dacryodes edulis

Antimicrobial Activities of Chrysophyllum Albidum Leaves, Fruits and Seeds

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