Antimicrobial Activity of<i>Centaurea</i>. Species

Güven, Kıymet; Çelik, Sezgin; Uysal, İsmet

doi:10.1080/13880200590903390

Cited by 38 publications

(29 citation statements)

References 15 publications

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“…In this study, we obtained similar results with the earlier study 11 showing that ethyl acetate extracts of the plants were the most active.…”

Section: Resultssupporting

confidence: 82%

“…In the previous study 11 of antimicrobial activity of other Centaurea species namely, C. ptosomipapapoides, C. odyssei, C. ptosomipappa and C. kurdica, it was found that the extracts exhibited antibacterial and antiyeast effect and ethyl acetate extracts showed the most significant inhibitory activity. In this study, we obtained similar results with the earlier study 11 showing that ethyl acetate extracts of the plants were the most active.…”

Section: Resultsmentioning

confidence: 99%

“…Microdilution assay: The minimal inhibition concentration (MIC) values were also studied for the microorganisms which were determined as sensitive to the extracts in agarwell diffusion assay 11,24,25 . Stock solution of the ethyl acetate extract which gave the best inhibition in the agar-well diffusion test was prepared in dimethyl sulfoxide (DMSO, Carlo-Erba, France).…”

Section: Introductionmentioning

confidence: 99%

“…Many species of genus Centaurea L. (Asteraceae) have traditionally been used for the treatment of various ailments 3,4 . The genus Centaurea has been the subject of many antimicrobial and antioxidant activity properties [5][6][7][8][9][10][11][12][13][14][15][16][17] . The plants possess potent bioactive compounds capable of preventing and treating most oxidative related diseases.…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial and Antioxidant Activities of Some Species of Centaurea Collected from Turkey

Uysal¹,

Çelik²,

Saglam³

et al. 2013

Asian J. Chem.

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The antimicrobial activity of the ethanol, acetone, ethyl acetate and chloroform extracts from Centaurea persica Boiss., C. polyclada DC. and C. consanguinea DC. (Asteraceae) were investigated by agar-well diffusion assay. All of the extracts exhibited an antimicrobial effect against most of the bacteria and all of the yeasts tested. The plant extracts were also screened for radical scavenging potential using a 1,1-diphenyl-2-picryl-hydrazyl (DPPH) in vitro model system for antioxidant activity. Ethyl acetate extracts showed the most significant inhibitory activity. Therefore, the minimal inhibitory concentration (MIC) of only ethyl acetate extracts of the samples was determined and C. consanguinea showed the highest antimicrobial effect. However, the ethanol extract of C. polyclada at 0.5 mg/mL concentration displayed the highest antioxidant activity. This activity was followed by ethanol extracts of. C. persica, ethyl acetate extracts of C. polclada, C. persica and C. consanguinea respectively.

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“…In this study, we obtained similar results with the earlier study 11 showing that ethyl acetate extracts of the plants were the most active.…”

Section: Resultssupporting

confidence: 82%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Antimicrobial and Antioxidant Activities of Some Species of Centaurea Collected from Turkey

Uysal¹,

Çelik²,

Saglam³

et al. 2013

Asian J. Chem.

Self Cite

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“…[4,6] Members of Centaurea species were proposed to have antimicrobial, [5,[7][8][9][10] antifungal, [8,11] anti-inflammatory, [12] anti-ulcerogenic, [13] antioxidant, [14][15][16][17] antiplasmodial, [18] antiprotozoal, [8] antiviral [19] and cytotoxic [18,[20][21][22] activities. C. calcitrapa which grows up on northwestern Anatolia is used (2-6% infusion) as a fever reducer.…”

mentioning

confidence: 99%

Total Phenolic Contents, Antioxidant Activities Cytotoxicity of Three Centaurea Species: C. calcitrapa subsp. calcitrapa, C. ptosimopappa C. spicata

Erol-Dayi

Pekmez

Bona

et al. 2011

Free Radicals and Antioxidants

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Background: Many species of the genus Centaurea have been reported to be used in Anatolian folk medicine. In the present study, methanolic and aqueous extracts of three species of Centaurea L. (C. calcitrapa subsp. calcitrapa, C. ptosimopappa and C. spicata) have been assessed for antioxidant and cytotoxic activities. Materials and Methods: Antioxidant activity was investigated by DPPH and superoxide anion scavenging and anti-lipid peroxidation assays. Cytotoxic effect on HeLa and Vero cells were investigated by MTT assay. Results: Superoxide anion scavenging activities of aqueous extracts were higher than those of methanolic extracts, and the highest activity was detected in the aqueous extracts of C. calcitrapa subsp. calcitrapa with the IC 50 value of 25.91 µg/mL. The methanolic extract of C. ptosimopappa showed the strongest anti-lipid peroxidation activity. Total phenolic contents (mg gallic acid equivalent per gram) were ranged between 17.25 and 120.50 and the highest value was detected in aqueous extract of C. ptosimopappa. The highest cytotoxic activity was observed in the methanolic extract of C. calcitrapa subsp. calcitrapa on both cell lines with the IC 50 values of <100 µg/mL. Conclusions: According to the results of activity tests, the selected Centaurea species, especially C. calcitrapa subsp. calcitrapa can be regarded as a potential source of natural antioxidants in the prevention and treatment of diseases in which oxidants or free radicals are implicated.Key-words: Antioxidant activity; Centaurea; Cytotoxicity; Free radical scavenging.Key Messages: The selected Centaurea species showed an antioxidant activity and very low cytotoxic activity. Thus, Centaurea species might be a good candidate for further studies targeting the development of new antioxidants.

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HPLC analysis, Phytochemical Content, and Biological Effects of Centaurea kilae Against Some Metabolic Enzymes: In Vitro and In Silico Studies

et al. 2023

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The aim of this work was to quantify and identify the phenolic composition of Centaurea kilae Bosse and record the antialzheimer, anti-urease, anti-lipase, antidiabetic, anti-melanogenesis, and antibacterial properties. IC 50 values for enzymes were obtained between 0.370-180.1 μg/mL and this plant inhibited HMG_CoA R and urease enzymes more with IC 50 values of 0.370 and 39.09 μg/mL, respectively. Furthermore, molecular docking calculations were done subsequently, using targets, HMGCoA_R, glucosidase, amylase, and lipase to detect the structural necessity in activity for the phenolic compounds of Centaurea kilae plant. Chemical compounds of methanolic extracts of Centaurea kilae determined in this work. Finally, antibacterial and antifungal effects of this plant investigated.

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Antimicrobial Activity ofCentaurea. Species

Cited by 38 publications

References 15 publications

Antimicrobial and Antioxidant Activities of Some Species of Centaurea Collected from Turkey

Antimicrobial and Antioxidant Activities of Some Species of Centaurea Collected from Turkey

Total Phenolic Contents, Antioxidant Activities Cytotoxicity of Three Centaurea Species: C. calcitrapa subsp. calcitrapa, C. ptosimopappa C. spicata

HPLC analysis, Phytochemical Content, and Biological Effects of Centaurea kilae Against Some Metabolic Enzymes: In Vitro and In Silico Studies

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