Antimicrobial activity of Ulopterol isolated from Toddalia asiatica (L.) Lam.: A traditional medicinal plant

Antidiabetic and antioxidant activities of Toddalia asiatica (L.) Lam. leaves in Streptozotocin induced diabetic rats

“…The standard solution was prepared by dissolving 1.75 mg of the compound in 100 ml of methanol. The HPLC validation parameters were determined and published in our previous report (Karunai Raj et al, 2012).…”

“…The plant is found in South Africa, Sri Lanka, and in the lower subtropical Himalaya, South India, Western Nilgiri, Palani hills and Tirunelveli district (Chopra et al, 1956). The leaves are used to treat lung and skin diseases, rheumatism (Karunai Raj et al, 2012;Duraipandiyan and Ignacimuthu, 2009), stomach ache, to relieve pain in the bowel and as tooth power (Rajkumar et al, 2010). The flowers are used as an external application in wasp-stings; unripe fruit is used as a stimulant liniment for arthritis, and also for cough and throat pain; root and leaves are used for common cold and cough (Rajkumar et al, 2010).…”

“…Moreover, T. asiatica whole plant has been used along with Terminalia chebula, Terminalia bellirica, Eclipta alba, Enicostemma littorale in a polyherbal formulation for the treatment of diabetes (Hemalatha et al, 2006). Flindersine (Duraipandiyan and Ignacimuthu, 2009), hexacosanoic acid and b-sitosterol from leaves (Muthumani et al, 2010), two new geranyloxycoumarins, namely 7-geranyloxy-5-methoxycoumarin and 8-geranyloxy-5, 7-dimethoxycoumarin from twigs (Wang et al, 2009), ulopterol from leaves (Karunai Raj et al, 2012), nitidine from root bark, toddasin, toddanol, toddanone, toddalenone and toddalidimerine from roots have been isolated from T. asiatica. Our preliminary studies revealed that the ethyl acetate extract of T. asiatica showed significant oral glucose tolerance and antidiabetic effects when compared with hexane and methanol extracts; hence phytochemical screening, total phenolic content and HPLC analysis of ethyl acetate extract were carried out.…”

Antimicrobial and Anti-Inflammatory Activity of Some Lathyrus L. (Fabaceae) Species Growing In Turkey

“…A series of tubes containing only inoculated broth were used as controls. After incubation for 18-24 at 37±1 ºC for bacteria, 48 h for fungi, the last tube with no microbial growth was recorded to represent MIC value (mg/mL) 16,17 .…”

Antimicrobial activity of Turkish Viurnum species

“…Minimum inhibitory concentrations (MIC) were determined with the effective Viburnum sp. extracts (Karunai-Raj et al 2012). The extracts were sterilized through a 0.45 µm membrane filter.…”