Antimicrobial and toxicological studies of some metal complexes of 4-methylpiperazine-1-carbodithioate and phenanthroline mixed ligands

Structural, spectral and potentiometric characterization, and antimicrobial activity studies of [Zn(phen)2(cnge)(H2O)](NO3)2 · H2O

“…o-Phenanthroline shows the lowest MIC values against the tested strains, as expected [39,40]. Complexation with Zn produced a decrease of the antimicrobial activity of o-phenanthroline but an increase of the effect of the metal on E. coli, S. aureus, and S. epidermidis.…”

New zinc(II) complexes of the Non-steroidal Anti-Inflammatory Drug (indomethacin) and various nitrogen donor ligands. Synthesis, characterization and biological activity

“…Many compounds possess modified pharmacological potentials when administered in the form of metal based compounds. Of the metal ions commonly used are cobalt, copper and zinc because of forming low molecular weight complexes and therefore, prove to be more beneficial against several diseases [32][33][34]. Carmen Sharaby have studied the effect of metallation on the antimicrobial activity of Schiff base namely 2-thiophene carboxaldehyde-sulfametrole.…”

DFT vibrational assignments, in vitro antifungal activity, genotoxic and acute toxicity determinations of the [Zn(phen)2(cnge)(H2O)](NO3)2·H2O complex

“…In this context, it is interesting to note the enormous importance of developing novel antimicrobial drugs for the treatment of infectious diseases [11,12]. The antimicrobial action of phen has been demonstrated on several bacterial and fungal strains [13,14]. Zinc is an essential element involved in many vital cellular reactions at its low endogenous concentrations.…”