Antimicrobial and Wound Healing Properties of Polyacrylonitrile-Moringa Extract Nanofibers

Fayemi, Omolola E.; Ekennia, Anthony C.; Katata-Seru, Lebokang; Ebokaiwe, Azubuike Peter; Ijomone, Omamuyovwi M.; Onwudiwe, Damian C.; Ebenso, Eno E.

doi:10.1021/acsomega.7b01981

Cited by 100 publications

(46 citation statements)

References 55 publications

(96 reference statements)

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“…Data from the study showed that Moringa influenced the healing properties of the material. At days 1, 4 and 7 of the wound dressing experiment, the percentage wound closure of the rat was the highest for the nanofiber containing 0.5 g of Moringa leaf extract (35, 87 and 95%, respectively) compared to the positive control medical gauze (29,75 and 93%, respectively) [38].…”

Section: Medicinal Plant Extracts In Wound Healingmentioning

confidence: 97%

The Potential Effect of Medicinal Plants for Cartilage Regeneration

Alaribe¹,

Razwinani²,

Maepa³

et al. 2019

Cartilage Tissue Engineering and Regeneration Techniques

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Any trauma to a joint such as sports injury can lead to osteoarthritis especially injuries that include torn cartilage, dislocated joints and ligaments. In sports injury specifically, most of the ointments in the market are only applied after physical activity. Repair of the bone and cartilage continues to be a challenge. Autologous and allografts are the gold standard for the treatment of the bone and cartilage. They have an invasive, open surgical procedure that requires the tissue to be harvested from an alternative site within the patient. South Africa is rich in native flora that is currently tapped as medicine by traditional healers. However, little is known about the natural products of our native flora and their potential to serve as a remedy for sports injuries, fracture healing and osteoarthritis. The grand purpose of the project is to explore medicinal plants of South Africa as a potential source for bone and tissue engineering of articular cartilage.

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Section: Medicinal Plant Extracts In Wound Healingmentioning

confidence: 97%

The Potential Effect of Medicinal Plants for Cartilage Regeneration

Alaribe¹,

Razwinani²,

Maepa³

et al. 2019

Cartilage Tissue Engineering and Regeneration Techniques

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“…So, the PAN nanofibers containing 0.5 g of M . oleifera extract exhibited the best antimicrobial and healing activity (Fayemi et al, 2018).…”

Section: The Types Of Plant Compounds Used In Electrospinningmentioning

confidence: 99%

“…Therefore, with increasing the concentration of the M. oleifera leaf extract, the healing properties also increased. So, the PAN nanofibers containing 0.5 g of M. oleifera extract exhibited the best antimicrobial and healing activity(Fayemi et al, 2018).4.1.16 | MangosteenGarcinia mangostana L. (G. mangostana) known as the Queen of Fruits, is a tropical fruit found in Southeast Asia. The G. mangostana skin used as a therapeutic agent for the treatment of diarrhea, fever, the skin infections, and wounds is the main component of Xanthone that is the bioactive substance in the skin of G. mangostana.…”

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confidence: 99%

Medicinal plants used in wound dressings made of electrospun nanofibers

Fatehi

Abbasi

2020

J Tissue Eng Regen Med

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Nanofibers are a type of nanostructures, which due to their unique properties can be used in wound dressing, and electrospinning is a good way to produce them. The benefits of wound dressings made of electrospun nanofibers include a large surface area to volume ratio, high absorption of secretions from the wound, and high air permeability, mimicking the morphology of extracellular matrix (ECM) of the damaged tissue and the possibility of the gradual release of the drug agents loaded on nanofibers. Because of the adaptability of plants to the body, low side effects and the prevalence of antibiotic resistance, interest in using plants is increasing. Combining nanofibers with plants is a way to integrate the physical properties of the structure of nanofibers and the chemical and antibacterial properties of the plants. In recent years, many plants in the forms of extracts, essential oils, and pure active ingredients have been used in the electrospininng and production of nanofibercontaining plants; some of the plants may be a good choice for wound dressings made of electrospun nanofibers.

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“…Blending PAN with cellulose acetate can be used to increase the absorption properties of activated carbon nanofi bres [52]. PAN/gelatine blends can be used for the promotion of cell growth ( Figure 2) [53][54][55].…”

Section: Electrospinnable Polymer Materials For Wound Dressing Applicmentioning

confidence: 99%

Review of Possible Applications of Nanofibrous Mats for Wound Dressings

Mamun¹

2019

TEK

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Skin is an important part of the human body. Its function is to control the body's homeostasis mechanism. If a skin injury occurs, it is of utmost importance to heal the skin as soon as possible. The currently available medical treatment system, however, has limited eff ectiveness on the regeneration of the structure and function of the injured skin, potentially causing wound infections and dehydration. The corresponding impact on the healing process may in the worst case also be fatal. To overcome these problems in wound dressing materials, nanofi brous mats are excellent candidates for wound treatment and management. Such wound dressings can be found in biomedical applications not only in drug delivery, but also as antibacterial and antimicrobial materials, and as materials for the regeneration and repair of tissue or organs. The large surface-area-to-volume ratio is one of the unique properties of nanofi brous mats. This paper gives a brief overview of possible materials and applications of nanofi brous mats for wound dressing.

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Antimicrobial and Wound Healing Properties of Polyacrylonitrile-Moringa Extract Nanofibers

Cited by 100 publications

References 55 publications

The Potential Effect of Medicinal Plants for Cartilage Regeneration

The Potential Effect of Medicinal Plants for Cartilage Regeneration

Medicinal plants used in wound dressings made of electrospun nanofibers

Review of Possible Applications of Nanofibrous Mats for Wound Dressings

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