“…Melker et al (59) showed that tetracyclinemedicated gutta-percha was more effective at growth inhibition than standard gutta-percha for the strains tested: Actinomyces israelii, Actinomyces naeslundii, E. faecalis, and Fusobacterium nucleatum. In the same manner, Baer and Maki (51) evaluated the antimicrobial effect of mixing amoxicillin with different sealers and reported that sealers mixed with amoxicillin significantly inhibited the growth of E. faecalis compared with sealers without amoxicillin.…”