Antimicrobial Silver/Sodium Carboxymethyl Cotton Dressings for Burn Wounds

Abstract

Antimicrobial Ag/Na carboxymethyl cotton burn dressings are developed by partial cation exchange of sodium by silver from sodium carboxymethyl cotton gauze/nonwovens through treatment with silver nitrate in an 85/15 ethanol/water medium. The ethanol/water medium is necessary to preserve the fibrous form of carboxymethyl gauze/nonwovens with a degree of substitution of 0.3 to 0.4. From the behavior of antimicrobial release and the suppression of bacterial and fungal proliferation, it is apparent that the dressings containing the silver antimicrobial agent will protect wound surfaces from microbial invasion and effectively suppress bacterial proliferation. Antimicrobial evaluations of Ag/Na carboxymethyl cotton at North American Science Associates and the Southern Regional Research Center are positive. Additionally, the results show that an enhanced burn treatment is possible using a highly moisture retentive sodium carboxymethyl gauze instead of conventional gauze now used with silver nitrate. The carboxymethyl gauze’s capacity to hold a large amount of antimicrobial solution creates the possibility for better antimicrobial treatment. The retention of a greater amount of silver nitrate solution on the dressing will require less replenishment of solution on dressings on patients, which will reduce nursing time.

Antibacterial Activity of Synthesized Silver Nanoparticles by Simaroubaglauca Against Pathogenic Bacteria

“…Silver was being used in the field of medicine for antimicrobial applications such as burn therapy [3,4], removal of microbes on textile fabrics [5][6][7], and inhibition of colonization of bacteria on catheters [8][9][10]. As antimicrobial agents, Nano-silver systems offer many advantages.…”

Antimicrobial activities of silver nanoparticles synthesized from Lycopersicon esculentum extract

“…Therefore, there is an urgent need to develop new bactericides. Silver has been used for years in the medical field for antimicrobial applications such as burn treatment (Parikh et al 2005;Ulkur et al 2005), elimination of microorganisms on textile fabrics (Jeong et al 2005;Lee et al 2007;Yuranova et al 2003), disinfection in water treatment (Russell and Hugo 1994;Chou et al 2005), prevention of bacteria colonization on catheters (Samuel and Guggenbichler 2004;Alt et al 2004;Rupp et al 2004), etc. It has also been found to prevent HIV from binding to host cells (Sun et al 2005), but the effects of silver nanoparticles (AgNP) on microorganisms have not been developed fully.…”

Synthesis and characterization of silver/montmorillonite/chitosan bionanocomposites by chemical reduction method and their antibacterial activity

“…[1][2][3][4][5] Recently, different inorganic antibacterial materials, including AgNPs, have been expanded and some are in commercial use. 6 The antibacterial activity of AgNPscontaining materials can be used, for example, in medicines to treat infections in human skin, 7,8 dental materials, 9 catheters, 10,11 vascular grafts, 12 stainless steel materials, 13 arthroplasty, 14 and burn treatment, 15,16 as well as to prevent microorganism colonization on prostheses. 17 In addition, nanomaterials including AgNPs can be utilized for water treatment 18 and also for reducing bacteria on textile fabrics.…”