Antineoplastic, Bio-Chemical, Cytotoxic and Antimicrobial Investigation on Synthesized Schiff Base Co(II) Ion Complex

Kudrat-E-Zahan,; Hossain, Saddam; Haque, M. M.; Banu, Laila Arjuman; Matin, M. A.; Bitu, Nur Amin; Habib, Ahsan; Ashrafuzzaman, Md.; Uddin, Nayon; Islam, M. Saidul

doi:10.11648/j.bmb.20190403.11

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…To determine the susceptibility of the pathogenic microorganism to the synthesized compounds antibacterial screening was carried out. Among different methods the disc diffusion method is broadly admissible for performing the antibacterial screening of compounds [21][22][23][24][25]. The measured diameter of zone of inhibition for the activity of complexes are tabulated in Table 1.…”

Section: Antibacterial Activity Of the Metal Complexesmentioning

confidence: 99%

One Pot Synthesis of Cu(II) and Ni(II) Peroxo Complexes Containing Schiff Base: Physicochemical, Spectral and Antibacterial Investigations

Ali

Bitu

Hossain

et al. 2020

AJOCS

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Two new peroxo complexes of Cu(II) and Ni(II) ion containing Schiff base (SB) were synthesized and characterized by TLC, Elemental analyses, conductivity, magnetic moment measurements, UV-Vis. and IR and ESI-MS spectral studies. The Schiff base ligand derived from cinnamaldehyde and o-aminophenol participated in complexation through a single pot reaction. IR spectra showed that the Schiff base ligand coordinated to the metal ion through nitrogen of azomethine group and oxygen of hydroxyl group & peroxo group (O-O). Magnetic moment value coupled with electronic spectral data suggested a square planar geometry for both the complexes. The molar conductance values indicated the non-electrolytic nature of the complexes. Antibacterial activity of the complexes was tested against four pathogenic bacteria, two Gram-positive Staphylococcus aureus & Bacillus cereus and two Gram-negative Escherichia coli & Shigella dysenteriae with Kanamycin (K-30) standard. The result shows that Cu(II) complex exhibited more potential antibacterial activity than the Ni(II) complex against all the tested organisms.

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Section: Antibacterial Activity Of the Metal Complexesmentioning

confidence: 99%

One Pot Synthesis of Cu(II) and Ni(II) Peroxo Complexes Containing Schiff Base: Physicochemical, Spectral and Antibacterial Investigations

Ali

Bitu

Hossain

et al. 2020

AJOCS

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show abstract

“…[1] Schiff bases ligands and their transition metal complexes have a variety of applications including analytical, clinical, and biological applications as antibacterial, antifungal, anticancer, antiviral, and antitumor agents. [2][3][4][5][6] The significance of metal ions is strongly established in biological systems. One of the most interesting features of metalcoordinated systems is the concerted spatial arrangement of the ligands around the metal ion.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization and Biological Activity of Oxovanadium(IV) Complexes Containing α-Amino Acid Schiff Bases and 5,6-Dimethyl-1,10-phenanthroline Ligands

et al. 2020

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Five oxovanadium(IV) complexes of the type [VO(L)(DPhen)], containing Schiff base derived from α-amino acid, [where L = 3-hydroxybenzaldehyde-α-alanine (hb-Ala), 3-hydroxybenzaldehyde-DL-phenylalanine (hb-Phe), 3-hydroxybenzaldehyde-leucine (hb-Leu), 3-hydroxybenzaldehyde-glycine (hb-Gly) and 3-hydroxybenzaldehyde-DL-methionine (hb-Met) & DPhen = 5,6-Dimethyl-1,10-phenanthroline] have been synthesized and characterized by some physicochemical properties, molar conductance, magnetic susceptibilities measurements, elemental analysis, UV-Visible, FT-IR and EIS-MS spectral studies. The molar conductance values evidenced the non-electrolytic nature of the complexes. The magnetic moment values of the complexes are in accordance with the d 1 electronic configuration of the V IV O 2+ moiety and indicates the paramagnetic behavior of the complexes. IR spectral data indicates the coordination of tridentate amino acid Schiff base ligands to the vanadyl (VO 2+ ) ion through O, N, O-donor. ESI-MS spectral study confirmed the proposed structure of the complexes. All the analytical data suggested that all the complexes possess to have distorted octahedral geometry. The complexes were screened for their antibacterial activity against four human pathogenic bacteria; two Gram positive Escherichia coli & Pseudomonas aeruginosa and two Gram negative Staphylococcus aureus & Bacillus cereus with Kanamycin (K-30) standard. The result shows that all the complexes have moderate to strong potential antibacterial activity against all the pathogenic bacteria.

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Peroxo Complexes of Th(IV) and Zr(IV) Ions Containing Aspartic Acid and Amine Bases as Potential Biological Agents

et al. 2020

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Antineoplastic, Bio-Chemical, Cytotoxic and Antimicrobial Investigation on Synthesized Schiff Base Co(II) Ion Complex

Cited by 4 publications

References 12 publications

One Pot Synthesis of Cu(II) and Ni(II) Peroxo Complexes Containing Schiff Base: Physicochemical, Spectral and Antibacterial Investigations

One Pot Synthesis of Cu(II) and Ni(II) Peroxo Complexes Containing Schiff Base: Physicochemical, Spectral and Antibacterial Investigations

Synthesis, Characterization and Biological Activity of Oxovanadium(IV) Complexes Containing α-Amino Acid Schiff Bases and 5,6-Dimethyl-1,10-phenanthroline Ligands

Peroxo Complexes of Th(IV) and Zr(IV) Ions Containing Aspartic Acid and Amine Bases as Potential Biological Agents

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