Antioxidant activities of citrus herbal product extracts

Tetramethyl-O-scutellarin isolated from peels of immature Shiranuhi fruit exhibits anti-inflammatory effects on LPSinduced RAW264.7 cells

“…Polymethoxyflavones (PMFs) have attracted considerable attention as bioactive constituents in Citrus peels [2,7] owing to their antiinflammatory [8], anticarcinogenic [9], and antiatherogenic properties [10]. Besides, antioxidant [11,12] and antitumor properties [13] were also identified from the flavonoids of Citrus genus.…”

Antioxidative capacity of Iranian Citrus deliciosa peels

“…The IC 50 was 0.358 mg/ml. According to the studies carried out by Min-Sheng et al, IC 50 value of Citrus reticulata Blanco peels and C. reticulata Blanco immature peels were 0.78 and 0.46 mg/ml; [4] Ghasemi et al have recorded IC 50 , 1.1, 0.6, 1.9, 1.4, 2.1 mg/ml for experiments conducted with C. sinensis var, Washington Navel C. reticulata var. Ponkan, C. unshiu var.…”

“…The combined filtrate was filtered through 0.45 µm of filter membrane and evaporated with a rotary evaporator (4003, Heidolph, Germany) below 50 o C. After the evaporation of the organic solvent, it was used for further analysis. [4] Total flavonoid content determination…”

“…Flavonoids have a wide range of biological activities: cell-proliferation-inhibiting, apoptosis-inducing, enzyme-inhibiting, antibacterial and antioxidant effects. [4] Flavonoids: flavanones, flavones and flavonols occur in Citrus fruit. [5] The main flavonoids found in citrus peels are hesperidine, narirutin, 6.8-di-C-Glu-Apigenin, and 6,8-di-C-Glu-Diosmetin.…”

“…[7] Many papers have reported the antioxidants in juice and edible parts of oranges of different origin and varieties. [4,5,8,9] As far as the peels are concerned, extracts from this part of the fruit were found to have a good total radical antioxidative potential. The rind of Citrus is a huge waste; therefore, it can be used as a valuable and lowpriced source for natural antioxidant.…”