Antioxidant activity of horehound (Marrubium vulgare L.) grown in Lithuania

Weel, Koen G. C.; Venskutonis, Petras Rimantas; Pukalskas, Audrius; Gruzdienė, D.; Linssen, J.P.H.

doi:10.1002/(sici)1521-4133(199910)101:10<395::aid-lipi395>3.0.co;2-l

Cited by 51 publications

(40 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For this purpose the weight of 150 ml open beakers containing 25.00 g of oil was measured at timed periods during 9 days [25]. The extracts, 0.1% w/w each were dissolved in tested oils; blank sample was left without any additives.…”

Section: Assessment Of Antioxidant Activity (Aa)contrasting

confidence: 69%

Rapid screening of antioxidant activity of sage (Salvia officinalis L.) extracts obtained by supercritical carbon dioxide at different extraction conditions

Daukšas

Venskutonis²,

Povilaitytė

et al. 2001

Nahrung

View full text Add to dashboard Cite

Sage herb (Salvia officinalis L.) was extracted at supercritical fluid extraction (SFE) conditions with carbon dioxide at different parameters and the extracts tested on their antioxidant activity (AA). SFE of sage herb at 35 MPa pressure was found to be an effective method to obtain pure extracts. The yields of the extracts were substantially increased by using 1% of entrainer solvent ethanol. The fractionation of sage extract was a complex procedure in terms of extract distribution between separators operating at various pressure and temperature conditions. It was also proved by testing the AA of the extracts in rapeseed oil. The effect of the extracts on the rapeseed oil weight gain varied in a wide range (from 'very low' to 'high') depending on the fractionation conditions. Preliminary results showed that to obtain more effective antioxidant fractions separation steps should be started at 10 MPa lower pressure than that used for the extraction.

show abstract

Section: Assessment Of Antioxidant Activity (Aa)contrasting

confidence: 69%

Rapid screening of antioxidant activity of sage (Salvia officinalis L.) extracts obtained by supercritical carbon dioxide at different extraction conditions

Daukšas

Venskutonis²,

Povilaitytė

et al. 2001

Nahrung

View full text Add to dashboard Cite

show abstract

“…Previous studies have demonstrated that white horehound extracts exhibit antispasmodic (Schlemper et al, 1996), antioxidant (Berrougui et al, 2006;Matkowski and Piotrowska, 2006;Weel et al, 1999), hypotensive (El Bardai et al, 2001), insecticidal (Pavela, 2004), and analgesic (Meyre-Silva et al, 2005) properties. Marrubium species are rich in diterpenes, caffeic acid derivatives, sterols, and flavonoids (Khanavi et al, 2005;Lazari et al, 1999).…”

Section: Marrubium Vulgare (Lamiaceae) -Maruggmentioning

confidence: 99%

Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence of methicillin-resistant Staphylococcus aureus

Quave

Plano

Pantuso

et al. 2008

Journal of Ethnopharmacology

262

176

View full text Add to dashboard Cite

One-third of botanical remedies from southern Italy are used to treat skin and soft tissue infection (SSTI). Staphylococcus aureus, a common cause of SSTI, has generated increasing concern due to drug resistance. Many plants possess antimicrobial agents and provide effective remedies for SSTI. Our aim was to investigate plants from different ethnobotanical usage groups for inhibition of growth and biofilms in methicillin-resistant S. aureus (MRSA).Three groups were assessed: plant remedies for SSTI, plant remedies not involving the skin, and plants with no ethnomedical application. We screened 168 extracts, representing 104 botanical species, for activity against MRSA (ATCC 33593). We employed broth dilution methods to determine the MIC after 18 hours growth using an optical density (OD 600nm ) reading. Anti-biofilm effects were assessed by growing biofilms for 40 hours, then fixing and staining with crystal violet. After washing, 10% Tween 80 was added and OD 570nm readings were taken.Extracts from 10 plants exhibited an IC 50 ≤32 μg/ml for biofilm inhibition: Lonicera alpigena, Castanea sativa, Juglans regia, Ballota nigra, Rosmarinus officinalis, Leopoldia comosa, Malva sylvestris, Cyclamen hederifolium, Rosa canina, and Rubus ulmifolius. Limited bacteriostatic activity was evident. The anti-biofilm activity of medicinal plants was significantly greater than plants without any ethnomedical applications.

show abstract

“…In Lithuania, the volatile components of M. vulgare were hydrodistilled and analyzed by gas chromatography (GC) and GC mass spectrometry (MS). The major constituents of the essential oil were reported as β-bisabolene, δ-cadinene, and isocaryophyllene [51]. In Egypt, Salama et al [52] reported that thymol and γ-cadinene as were the major constituents of M. vulgare oil.…”

Section: Essential Oil Including Monoterpenes and Sesquiterpenesmentioning

confidence: 99%

“…The methanolic extract of M. vulgare leaves showed potent antioxidant power against 2,2-diphenyl-1-picrylhydrazyl (DPPH) (IC 50 = 35 µg/ml) and 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) (IC 50 = 25 µg/ml) radicals scavenging. The antioxidant activity of acetone and water extracts obtained from leaves of M. vulgare was tested in rapeseed (Brassica napus L.) oil at 80°C [51]. The effect of the extracts was assessed by measuring peroxide value, weight gain, and ultraviolet absorption.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Marrubium vulgare L.: A review on phytochemical and pharmacological aspects

Lodhi¹,

Vadnere²,

Sharma³

et al. 2017

J Intercult Ethnopharmacol

View full text Add to dashboard Cite

Marrubium vulgare L. (family: Lamiaceae), also known as the white horehound, is widely used as an herbal remedy for chronic coughs and colds. It is used in various disorders related to skin, liver, gastric, heart, and immune system. This review abridges phytochemical, pharmacological studies, and medicinal uses of M. vulgare and provides scientific proof for various ethnobotanical claims to identify gaps, which will give impulsion for novel research on M. vulgare based herbal medicines. This review summarizes selected scientific evidence on phytochemistry and pharmacological properties of M. vulgare over the past 48 years . Works related to M. vulgare was reviewed from various sources such as books, internet source, i.e., Google Search engine, PubMed, and Science Direct, and chemical abstract. The exhaustive literature was studied, and critical analysis was performed according to their phytochemical and pharmacological properties. Phytochemical investigations on different parts of M. vulgare have been reported the presence of flavonoids, steroids, terpenoids, tannins, saponins, and volatile oils (0.05%). The aerial parts contain marrubiin, together with ursolic acid and choline. Pharmacological activities such as antinociceptive, antispasmodic, antihypertensive, antidiabetic, gastroprotective, anti-inflammatory, antimicrobial, anticancer, antioxidant, and antihepatotoxic activity have been reported. M. vulgare has therapeutic potential in the treatment of inflammatory conditions, liver disorders, pain, cardiovascular, gastric, and diabetic conditions. Aerial parts of M. vulgare is a good source of labdane type diterpene especially marrubiin which is present in high concentrations. However, further scientific studies are needed to explore clinical efficacy, toxicity and to explore the therapeutic effect of major secondary metabolites such as diterpenes, phenylpropanoid, and phenylethanoid glycosides of M. vulgare.

show abstract

Antioxidant activity of horehound (Marrubium vulgare L.) grown in Lithuania

Cited by 51 publications

References 22 publications

Rapid screening of antioxidant activity of sage (Salvia officinalis L.) extracts obtained by supercritical carbon dioxide at different extraction conditions

Rapid screening of antioxidant activity of sage (Salvia officinalis L.) extracts obtained by supercritical carbon dioxide at different extraction conditions

Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence of methicillin-resistant Staphylococcus aureus

Marrubium vulgare L.: A review on phytochemical and pharmacological aspects

Contact Info

Product

Resources

About