Antioxidant and Antibacterial Activities of Glycyrrhiza uralensis Fisher (Jecheon, Korea) Extracts Obtained by various Extract Conditions

Ha, Ji Hoon; Jeong, Yoon; Seong, Joon Seob; Kim, Kyoung Mi; Kim, A Young; Fu, Min Min; Suh, Ji Young; Lee, Nan Hee; Park, Jino; Park, Soo Nam

doi:10.15230/scsk.2015.41.4.361

Cited by 5 publications

(2 citation statements)

References 17 publications

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“…In addition, UV irradiation to the skin activates collagenases within the skin, which degrades collagen that contributes to the elasticity of the skin, and accelerates the dryness and aging of the skin (Imokawa et al, 2015). As these studies show, excessive oxidative stress generated by continuous exposure to UV light cuts the chains of collagen, elastin and hyaluronic acid and accelerates the creation of melanin, which reduces skin elasticity and causes skin aging along with wrinkles and pigmentation (Ha et al, 2015;Xuan et al, 2016). The increasing activity of keratinocytes caused by UVB irradiation induces the creation of cytokines, and activates fibroblasts, generating cytokines and the expression of MMP -1 proteins (Kim et al, 2018).…”

Section: Assessment Of In-vivo Anti-photoaging Effectmentioning

confidence: 99%

Inhibitory Effects of Collagen Coated Coffee Bean Intake on Skin Aging

Lee¹,

Ha²,

Shin³

2019

J. People Plants Environ

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To evaluate the protective effect of collagen peptide-coated coffee extract on skin aging, cell viability was measured with a MTT assay using cultured CCD-986sk fibroblasts, and its effect on wrinkles in the skin of hairless mice induced by UVB-irradiation was examined. In addition, its effect on procollagen synthesis and anti-oxidative, and its inhibitory activity against collagenase, elastase, tyrosinase and MMP-1 were analysed. After the 30-minute topical treatment, the animals were exposed to UVB irradiation (60-100 mJ/cm 2) for 4 weeks and its intensity increased during the period. Under the experimental conditions set in this study, the skin thickness of hairless mice significantly decreased (11.8-21.3%) compared to the control group. Based on these results, the prolonged oral intake of a collagen peptide mixture with coffee is expected to significantly increase the synthesis of procollagen in dermal fibroblasts, thereby contributing to the alleviation of wrinkling and lowered elasticity due to structural damage to the dermal layer caused by UV. The oral intake of collagen-coated coffee contributes to increasing collagen biosynthesis in a dose-dependent manner and alleviates the symptoms of thickened keratin caused by UV irradiation. However, it did not inhibit the enzymes involved in skin aging, whitening, wrinkle improvement, and antioxidation. Based on the these results, it can be concluded that the intake of collagen peptide-coated coffee extract can be utilized as an alternative material for the prevention or treatment of diseases associated with photoaging.

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Section: Assessment Of In-vivo Anti-photoaging Effectmentioning

confidence: 99%

Inhibitory Effects of Collagen Coated Coffee Bean Intake on Skin Aging

Lee¹,

Ha²,

Shin³

2019

J. People Plants Environ

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“…사람이 외부 활동하면서 태양광선을 받았을 때, 자외선이 직접적으로 작용하는 부위는 피부에 있어서도 제일 외부에 있는 각질형성세포로 구성된 표피이다 [2,3]. 자 [7][8][9].…”

Section: 서 론unclassified

Antioxidant and Cellular Protective Effects against Oxidative Stress of Calendula officinalis Flowers Extracts in Human Skin Cells

Xuan¹,

Kim²,

Yu³

et al. 2016

Applied Chemistry for Engineering

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In this study, we investigated the total phenolic and flavonoid contents, antioxidant activity and cellular protective effects against oxidative stress on human skin cells in 50% ethanol extract and its fractions of Calendula officinalis (C. officinalis) flowers. We measured the antioxidant effects of 50% ethanol extract and its fractions of C. officinalis flowers on the free radical scavenging activity (FSC50), the reactive oxygen species (ROS) scavenging activities (OSC50) and the inhibition of intracellular ROS generation in human skin cells. These results showed that the antioxidant effect of the ethyl acetate and aglycone fraction was more than the 50% ethanol extract of C. officinalis flowers. We also investigated the cellular protective activity and the results showed that treatment of the ethyl acetate fraction (0.05 -3.13 µg/mL) protects human skin cells in a concentration-dependent manner when the skin cell damages were induced by treating them with H2O2. In addition, the aglycone fraction (1.56 -3.13 µg/mL) shows cellular protective effects on the UV-induced cell damages in a dose-dependent manner. These results suggest that the fractions of C. officinalis flowers can function as a natural antioxidant agent of cosmetics in human skin cells exposed to oxidative stress by ROS scavenging effects.

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Comparison between the Biological Activities of Leaf and Flower Extracts of Osmanthus fragrans var. aurantiacus and Osmanthus asiaticus Lour. var. fragrans

Yoon

2023

Asian J Beauty Cosmetol

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Purpose: This study aims to verify the biological activities of leaf and flower extracts of Osmanthus fragrans var. aurantiacus (OF) and Osmanthus asiaticus Lour. var. fragrans (OA), which can be used in the cosmetics industry.Methods: Ethanol extraction of the flowers and leaves of OF and OA was performed to determine the total polyphenol and flavonoid content, the scavenging activities of DPPH and ABTS radicals, the inhibitory effects on elastase and tyrosinase, and antibacterial effects.Results: The total polyphenol content of leaf and flower extracts was determined to be 135.64 μg/mL and 80.06 μg/mL, respectively, for OF and 104.11 μg/mL and 71.64 μg/mL, respectively, for OA. The total flavonoid content of leaf and flower extracts was found to be 123.48 μg/mL and 86.20 μg/mL, respectively, for OF and 104.07 μg/mL and 78.13 μg/mL, respectively, for OA. At a concentration of 500 μg/mL, the DPPH scavenging activity of leaf and flower extracts was found to be 84.49% and 72.08%, respectively, for OF and 77.12% and 68.75%, respectively, for OA. The ABTS radical scavenging activity of leaf and flower extracts was determined to be 90.36% and 83.15%, respectively, for OF and 88.14% and 80.90%, respectively, for OA. The inhibitory effect of leaf and flower extracts on elastase was confirmed to be 58.31% and 46.14%, respectively, for OF and 51.22% and 39.26%, respectively, for OA. The inhibitory effects of leaf and flower extracts on tyrosinase were found to be 57.24% and 48.12%, respectively, for OF and 52.15% and 41.12%, respectively, for OA. Upon evaluation, the leaf and flower extracts of OF and OA exhibited antibacterial effects on Propionibacterium acnes (P. acnes) and Malassezia furfur (M. furfur).Conclusion: Among the ethanol extracts of the leaves and flowers of both species, the leaf extract of OF was confirmed to have not only an antioxidant effect but also a high inhibitory effect on elastase and tyrosinase, along with antibacterial effects. Therefore, it is expected to have high potential as a cosmetic material.

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Antioxidant and Antibacterial Activities of Glycyrrhiza uralensis Fisher (Jecheon, Korea) Extracts Obtained by various Extract Conditions

Cited by 5 publications

References 17 publications

Inhibitory Effects of Collagen Coated Coffee Bean Intake on Skin Aging

Inhibitory Effects of Collagen Coated Coffee Bean Intake on Skin Aging

Antioxidant and Cellular Protective Effects against Oxidative Stress of Calendula officinalis Flowers Extracts in Human Skin Cells

Comparison between the Biological Activities of Leaf and Flower Extracts of Osmanthus fragrans var. aurantiacus and Osmanthus asiaticus Lour. var. fragrans

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