Antioxidant and Biological Activities of the Lotus Root Polysaccharide-Iron (III) Complex

Yuan, Shuai; Dong, Pei-Yu; Ma, Hao-Hai; Liang, Sheng-Lin; Li, Long; Zhang, Xi-Feng

doi:10.3390/molecules27207106

Cited by 16 publications

(7 citation statements)

References 37 publications

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“…The absorption peak of the PCP1C-iron (III) complex at 850 cm −1 indicated that the iron in PCP1C-iron (III) complex existed in the form of the β-FeOOH iron core [ 22 ]. The carbonyl absorption peak at 1666 cm −1 indicated that Fe (III) complexes with carbonyl caused a change in carbonyl vibration dipole moment [ 5 ]. The absorption peak at 3413 cm −1 was the vibration absorption peak of the hydroxyl group in the polysaccharide molecule [ 32 ], and the absorption peak was narrowed after complexing with Fe (III), indicating that the hydroxyl group in the polysaccharide participated in the complexation reaction.…”

Section: Resultsmentioning

confidence: 99%

“…Among them, polysaccharide iron represented by Niferex has attracted considerable attention because of its stable structure, high bioavailability, and high iron content [ 4 ]. In addition, polysaccharide iron not only has the activity of supplementing iron, but also has other beneficial activities of polysaccharide [ 5 – 8 ]. Although polysaccharide iron has been recognized as a potential drug to treat IDA, the clinical application of polysaccharide iron prepared from plant polysaccharides is limited at present, which may be related to the unclear activity of polysaccharide iron and the low purity of polysaccharide.…”

Section: Introductionmentioning

confidence: 99%

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Preparation, characterization, antioxidant and antianemia activities of Poria cocos polysaccharide iron (III) complex

Zhang

Huang

Sun

et al. 2023

Heliyon

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Preparation, characterization, antioxidant and antianemia activities of Poria cocos polysaccharide iron (III) complex

Zhang

Huang

Sun

et al. 2023

Heliyon

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“…Thus, the sweet corn cob polysaccharide-iron (III) complex is more thermally stable. Moreover, introducing iron (III) binding to −OOH and −OH in polysaccharides leads to a more stable β-FeOOH iron core [ 28 ]. Therefore, it can significantly improve the stability of the complex compared to that of SCCP.…”

Section: Resultsmentioning

confidence: 99%

Structural Characterization, In Vitro Digestion Property, and Biological Activity of Sweet Corn Cob Polysaccharide Iron (III) Complexes

Xiu

Wang

et al. 2023

Molecules

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This study aimed to enhance the utilization value of sweet corn cob, an agricultural cereal byproduct. Sweet corn cob polysaccharide-ron (III) complexes were prepared at four different temperatures (40 °C, 50 °C, 60 °C, and 70 °C). It was demonstrated that the complexes prepared at different temperatures were successfully bound to iron (III), and there was no significant difference in chemical composition; and SCCP-Fe-C demonstrated the highest iron content. The structural characterization suggested that sweet corn cob polysaccharide (SCCP) formed stable β-FeOOH iron nuclei with −OH and −OOH. All the four complexes’ thermal stability was enhanced, especially in SCCP-Fe-C. In vitro iron (III) release experiments revealed that all four complexes were rapidly released and acted as iron (III) supplements. Moreover, in vitro antioxidant, α-glucosidase, and α-amylase inhibition studies revealed that the biological activities of all four complexes were enhanced compared with those of SCCP. SCCP-Fe-B and SCCP-Fe-C exhibited the highest in vitro antioxidant, α-glucosidase, and α-amylase inhibition abilities. This study will suggest using sweet corn cobs, a natural agricultural cereal byproduct, in functional foods. Furthermore, we proposed that the complexes prepared from agricultural byproducts can be used as a potential iron supplement.

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“…In this paper, an evaluation about the effects of the supplementation of dietary CYP-Cu on serum antioxidative parameters of broilers demonstrated that dietary CYP-Cu significantly increased the serum concentrations of T-SOD, T-AOC, GSH-ST, GSH-Px, and decreased the serum concentrations of MDA of broilers (0.10 g/kg CYP-Cu group), which revealed that CYP-Cu had strong antioxidant activity. A previous study shown that lotus root polysaccharide iron complex could significantly increase the antioxidant capacity of mice by increasing the serum levels of CAT, SOD, and GSH-Px ( 31 ), and showed a trend of first increasing from 2 to 8 mg/mL and then decreasing. Similarly, Dong et al ( 32 ) found that Flammulina velutipes polysacchrides and polysacchride-iron (III) complex inhibited the MDA production of health mice liver and improve its antioxidant capacity.…”

Section: Discussionmentioning

confidence: 99%

Effects of dietary Chinese yam polysaccharide copper complex on growth performance, immunity, and antioxidant capacity of broilers

Zhang

Jin²,

Cao³

et al. 2023

Front. Vet. Sci.

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Chinese yam polysaccharide (CYP) has received attention in recent years owing to its positive nutritional and medicinal characteristics. Copper is an essential trace metal in animals, which plays an important role in iron absorption and hemoglobin synthesis. However, no published study has evaluated Chinese yam polysaccharide copper complex (CYP-Cu) as a dietary additive in broilers. This study was conducted to investigate the effects of dietary CYP-Cu on growth performance, immunity, and oxidative resistance in broilers. A total of 360 1-day-old 817 broiler chickens were randomly divided into 4 groups, with 3 replicates of 30 birds each and were fed a basal diet with the addition of 0 (control group), 0.02, 0.10, and 0.50 g/kg CYP-Cu. The feeding trial lasted 48 days. On day 28 and day 48, 6 broilers in each group were slaughtered, respectively. Then the parameters of growth and carcass, serum biochemistry, immunity, and antioxidation, and the expression level of hepatic antioxidative genes were investigated. The results showed that compared with the control group, the supplementation of dietary CYP-Cu could improve the indexes of the growth, carcass, serum biochemistry, immunity and oxidation resistance in broilers, such as average daily gain (ADG), the slaughter percentage (SP), semi-evisceration weight percentage (SEWP), eviscerated carcass weight percentage (EWP), breast muscle percentage (BMP), leg muscle percentage (LMP), serum albumin (ALB), high density lipoprotein (HDL), insulin-like growth factor I (IGF-I), triiodothyronine (T3), thyroxine (T4), growth hormone (GH), insulin (INS), immunoglobulin M (IgM), immunoglobulin G (IgG), immunoglobulin A (IgA), interleukin 2 (IL-2), interleukin 4 (IL-4), interleukin 6 (IL-6), complement 3 (C3), complement 4 (C4), total superoxide dismutase (T-SOD), total antioxidative capacity (T-AOC), glutathione peroxidase (GSH-Px), and glutathione s-transferase (GSH-ST); these parameters in the 0.10 g/kg CYP-Cu treated group were significantly increased (P < 0.05) in the total trial period, with the exceptions that feed conversion ratio (FCR) and serum low density lipoprotein (LDL), malondialdehyde (MDA) were decreased in the total trial period. In addition, the antioxidative gene mRNA expression of Nuclear factor E2-related factor 2 (Nrf2), Superoxide dismutase 1 (SOD1), Superoxide dismutase 2 (SOD2), and Catalase (CAT) were upregulated in the liver (P < 0.05). These results indicated that the supplementation of dietary CYP-Cu improved the growth, immunity, and oxidation resistance of broilers, and the addition of 0.10 g/kg CYP-Cu in broiler diets is recommended, which suggests that CYP-Cu may be a promising green feed additive in the poultry industry.

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Antioxidant and Biological Activities of the Lotus Root Polysaccharide-Iron (III) Complex

Cited by 16 publications

References 37 publications

Preparation, characterization, antioxidant and antianemia activities of Poria cocos polysaccharide iron (III) complex

Preparation, characterization, antioxidant and antianemia activities of Poria cocos polysaccharide iron (III) complex

Structural Characterization, In Vitro Digestion Property, and Biological Activity of Sweet Corn Cob Polysaccharide Iron (III) Complexes

Effects of dietary Chinese yam polysaccharide copper complex on growth performance, immunity, and antioxidant capacity of broilers

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