Antioxidant and hepatoprotective Potential of Coriandrum sativum L. against hepatic injury by Lambda-cyhalothrin insecticide

Djahra, Ali Boutlelis; Benkaddour, Mounia; Benkherara, Salah; Bordjiba, Ouahiba

doi:10.22270/jddt.v10i3-s.4186

Cited by 7 publications

(4 citation statements)

References 23 publications

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“…Antifungal [25], Antidiabetic [26], Hepatoprotective [27], Haemato-protective [28]. For this reason, total phenolic content of Ephedra alata aerial parts were determined in this study.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Profile, Antioxidant and Antibacterial Activities of Ephedra alata Extract against Pathogenic Bacteria

Boutlelis¹,

Benkaddour²,

Benkherara

et al. 2022

JOCAMR

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Plants have been a source of important chemical compounds that can be used for treatment of different disease. Natural products in plants also are a source of active compounds and can be considered an alternative to synthetic molecules with high antioxidant potential. Objective of this study was to determine the antioxidant and antibacterial potential of Ephedra alata extract. Methods: Phytochemical values namely, total phenolic, DPPH radical scavenging effect were studied by established methods. Antimicrobial properties of Ephedra alata was tested using cup-plate diffusion method and disc diffusion. Results showed numerous secondary metabolic products including in plant Ephedra alata extract such as Flavonoids, Saponins, Tannins were detected. And other metabolic products such as Steroids and Cardinolids are absent. The yield for the aqueous extract was 9.89%. However, the polyphenols extract content was equal to 0.004243 (mg GAE/ml extract. Effectiveness of antioxidant plant using DPPH free root was estimated at IC50= 0.901 mg/ml for aqueous extract. In antibacterial screening, the extract showed antibacterial power with zone of inhibitions compared to positive controls Penicillin against multi-resistant germs such as: Pseudomonase aeruginosa and Serratia fonticola responsible of many infectious. Growth inhibition varies with bacterial species and concentration of Ephedra alta extract.

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“…Antifungal [25], Antidiabetic [26], Hepatoprotective [27], Haemato-protective [28]. For this reason, total phenolic content of Ephedra alata aerial parts were determined in this study.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Profile, Antioxidant and Antibacterial Activities of Ephedra alata Extract against Pathogenic Bacteria

Boutlelis¹,

Benkaddour²,

Benkherara

et al. 2022

JOCAMR

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“…Recent researchers have noticed similar changes in the hepatic tissues under the toxic xenobiotic effect. Therefore, all abnormalities appearing in liver tissues are attributed to oxidative stress, which is the primary mechanism behind all these degenerations [27][28][29]. In contract, treatment with deferent preparations, in particular, Ephedra alata alenda macerated extract, give a significant recovery in tissues, which can be attributed to bioactive substances in plant with a high concentration of polyphenols, which are responsible for its antioxidant activity and tissues-protective effects [30].…”

Section: Histopathological Observationmentioning

confidence: 99%

Antioxidant and Hepatoprotective Activity of Ephedra alata Extracts against Intoxication with Deltamethrin Pesticide in Male Rats

Djahra¹,

Zoubiri²,

Benkaddour³

et al. 2023

Pharmacophore

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“…Numerous studies have shown the therapeutic potential and ability of many secondary metabolites from herbal remedies, such as Hepatoprotective 3 Haemato-protective 4 , Antibacterial 5 , Antifungal 6 , Antidiabetic 7 , Cosmetics, and Food for their health benefits 8 . Consequently, finding powerful natural sources has become a top priority for creating novel drugs in the pharmaceutical sector 9 .…”

Section: Introductionmentioning

confidence: 99%

Traditional Herbal Remedies from Algeria for Treating Digestive Disorders

Boutlelis¹,

Lmhanat²,

Benkaddour³

et al. 2023

J. Drug Delivery Ther.

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Due to their efficiency in many treatments, the employment of herbal remedies has retained its importance for leading a human life. Traditional knowledge is passed from one generation to the next, which is protected. This research aimed to analyze traditional herbal remedies used in treating digestive disorders by El-Oued people (Southeastern Algeria). The research was conducted from September 2021 to June 2022. One hundred individuals, including thirty plant vendors, were selected from different regions. Personal interviews and questionnaires were employed to collect the data. SPSS version 20 and Microsoft Office Excel 2007 were used to organize the data and conduct the descriptive statistics analysis. This investigation enabled the discovery of 40 species in 16 families and different genres. Lamiaceae, with 22.5 % plants, were the most used sources for the treatment, and 54 % of herbs were spontaneous species. The use of seeds at 21 %, dry parts at 92 % and infusion method at 48 % was most commonly used in herbal remedies preparations. The participants cited Trigonella tibetana, Juniperus communis, and Punica granatum as sources of digestive disorders treatment. El-Oued region has an extremely high number of herbal remedy species, which suggests that the region's traditional medicine serves as a source of knowledge about medicinal plants for treating digestive disorders and illnesses associated with them. Keywords: Herbal remedies, Digestive disorders, Medicinal plants, Interviews.

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Antioxidant and hepatoprotective Potential of Coriandrum sativum L. against hepatic injury by Lambda-cyhalothrin insecticide

Cited by 7 publications

References 23 publications

Phytochemical Profile, Antioxidant and Antibacterial Activities of Ephedra alata Extract against Pathogenic Bacteria

Phytochemical Profile, Antioxidant and Antibacterial Activities of Ephedra alata Extract against Pathogenic Bacteria

Antioxidant and Hepatoprotective Activity of Ephedra alata Extracts against Intoxication with Deltamethrin Pesticide in Male Rats

Traditional Herbal Remedies from Algeria for Treating Digestive Disorders

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