Antioxidant enzymes and oxidative stress adaptation to exercise training: Comparison of endurance, resistance, and concurrent training in untrained males

Azizbeigi, Kamal; Stannard, Stephen R.; Atashak, Sirvan; Haghighi, Marjan Mosalman

doi:10.1016/j.jesf.2013.12.001

Cited by 80 publications

(62 citation statements)

References 24 publications

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“…In this study the increment in GHS level after 9 weeks of resistance training wasn't significant and this finding was inconsistent with numerous previous studies (1,2,4). This may be caused by difference in time sampling in this study toward inconsistent studies, because in all inconsistent studies blood sampling take placed in very time closer tremely 24 hours after termination of training).…”

Section: Discussioncontrasting

confidence: 80%

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The Effect of Resistance Training with Moderate and Progressive Intensity on Indices of Oxidative Stress (Serum 8-Isoprostane, Malondialdehyde and Reduced Glutathione Levels) in Young Healthy Men

Zabet

Ghazalian

Nik-Bakht

2018

J Clin Res Paramed Sci

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Background: 8-isoprostane(8-IsoP) and malondialdehyde (MDA) are novel and classic index of lipid per oxidation, respectively, and reduced glutathione (GSH) is an index of antioxidant status, which the chronic adaptation of moderate and progressive resistance training on them is unclear. The purpose of this study is to investigate and compare the effect of 9 weeks moderate and progressive resistance training on serum 8-isoprostane, malondialdehyde and reduced glutathione levels in young men (from 17-to 21 year-olds). Methods: In the semi-experimental study, 36 volunteers were randomly divided in to 3 groups of 12 men involving: moderate and progressive resistance training and control groups. The training protocol involved three periods of three weeks each with progressive intensity. The moderate training group performed the first period of protocol in throughout of study (just 5 percent increase in training intensity as overload), while the training load of progressive training group was incrementally increased in every period. Blood sampling were taken in two phases involving pre test and following ninth week from anterior brachial vein. The variables were measured via sandwich ELISA. Results:The results of ANCOVA and Bonferroni tests showed that 9 weeks of moderate and progressive resistance training led to significance decrease in lipid oxidation indices (8-IsoP and MDA);the range of the decline especially in serum 8-IsoP was more in progressive group. Significant change in serum GSH levels was not observed in the training groups. Conclusions:The results of this study show that periodic increase in resistance training load leads to improves in oxidative stress adaptability. Moreover, 8-IsoP is more accurate index for predicting oxidative stress compared to MDA.

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Section: Discussioncontrasting

confidence: 80%

“…Scientific findings shows that the resistance training can improve muscle strength, body composition and bone density (1). Moreover pervasive evidence shows that the regular resistance training even has useful effect on cardiovascular diseases associated with risk factor such as blood pressure and the levels of lipoproteins (2).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Resistance Training with Moderate and Progressive Intensity on Indices of Oxidative Stress (Serum 8-Isoprostane, Malondialdehyde and Reduced Glutathione Levels) in Young Healthy Men

Zabet

Ghazalian

Nik-Bakht

2018

J Clin Res Paramed Sci

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“…For example, SOD levels are commonly higher in the resting blood and muscle of trained individuals compared to those of control groups (Tiidus et al, 1996). Endurance training may increase the activities of SOD and GPx in both plasma and exercised muscles (Lambertucci et al, 2007; Brooks et al, 2008; Vieira Junior et al, 2013; Azizbeigi et al, 2014). This magnitude of exercise-mediated changes in SOD or GPx activities is dependent on the intensity and duration of that specific exercise.…”

Section: Ros-induced Adaptive Response To Exercisementioning

confidence: 99%

Redox Mechanism of Reactive Oxygen Species in Exercise

et al. 2016

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It is well known that regular exercise can benefit health by enhancing antioxidant defenses in the body. However, unaccustomed and/or exhaustive exercise can generate excessive reactive oxygen species (ROS), leading to oxidative stress-related tissue damages and impaired muscle contractility. ROS are produced in both aerobic and anaerobic exercise. Mitochondria, NADPH oxidases and xanthine oxidases have all been identified as potential contributors to ROS production, yet the exact redox mechanisms underlying exercise-induced oxidative stress remain elusive. Interestingly, moderate exposure to ROS is necessary to induce body's adaptive responses such as the activation of antioxidant defense mechanisms. Dietary antioxidant manipulation can also reduce ROS levels and muscle fatigue, as well as enhance exercise recovery. To elucidate the complex role of ROS in exercise, this review updates on new findings of ROS origins within skeletal muscles associated with various types of exercises such as endurance, sprint and mountain climbing. In addition, we will examine the corresponding antioxidant defense systems as well as dietary manipulation against damages caused by ROS.

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“…An extensive study on the effects of intense and exhaustive exercise [22] revealed an increase in MDA concentration by 131% in rats exposed to strenuous swimming. Azizbeigi et al [23] confi rmed a signifi cant increase in MDA concentration in athletes regardless of the type of intensive training. The assessment of lipid peroxidation during exercise was also carried out in race horses and reported on a signifi cant increase in plasma MDA values as long as 18h after the ride [24].…”

Section: Discussionmentioning

confidence: 95%

Effects Of Rose-Hip And Grapeseed Dietary Supplementation On Serum Oxidative Stress Parameters In Dogs Before And After Physical Exercise

Kukovska¹,

Celeska

Ruskovska

et al. 2015

Acta Veterinaria

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The aim of this study was to evaluate the effects of 60 days of rose-hip and grapeseed dietary supplementation of a balanced home-cooked diet on serum oxidative stress parameters: ROMs, MDA and FRAP in army service dogs before and after regular physical exercise. The dogs were fed a balanced cooked diet as instructed by army standards until the initial blood sampling in June. Thereon the dogs were randomly allotted to 4 groups according to the dietary regime: dogs maintained on a balanced cooked diet according to army standards, branded dry dog food, cooked diet with added 500 mg rose-hip extract, and cooked diet with added 100 mg grapeseed extract for a 60 day period from June to September after which all 4 groups were fed the standard cooked meal diet. Sampling was performed at the beginning of the experiment (June), 60 days from the start of the treatment (September) and finally 60 days after the end of supplementation (November). Statistical analysis of the results included descriptive statistical parameters: mean (M), standard deviation (SD), and variation coefficient (CV%). In order to test the statistical significance of the differences between treatments a multifactor variance test (ANOVA) was performed for ROM, MDA and FRAP and the combined effects of diet, exercise and time period were observed. The initial (in June) increase in MDA and ROMs after exercise indicates the presence of oxidative stress 30 minutes after exercise. However, the antioxidative effects of rose-hip and grapeseed extracts are not conclusive, as multifactor ANOVA testing of time, diet, and exercise factors did not reveal for MDA statistically significant differences either at 60 days of supplementation nor 60 days after withdrawal of the supplements. Only one distinct exception was recorded for the prolonged antioxidative effects reflected in significantly decreased (p<0.01) ROMs before and after exercise in dogs fed the branded dry food 60 days after the end of such dietary regime (November). FRAP values tend to be higher (p>0.05) after exercise compared to before exercise in all experimental groups in November, indicating on a possible redistribution and upregulation of endogenous antioxidants during the experiment.

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Antioxidant enzymes and oxidative stress adaptation to exercise training: Comparison of endurance, resistance, and concurrent training in untrained males

Cited by 80 publications

References 24 publications

The Effect of Resistance Training with Moderate and Progressive Intensity on Indices of Oxidative Stress (Serum 8-Isoprostane, Malondialdehyde and Reduced Glutathione Levels) in Young Healthy Men

The Effect of Resistance Training with Moderate and Progressive Intensity on Indices of Oxidative Stress (Serum 8-Isoprostane, Malondialdehyde and Reduced Glutathione Levels) in Young Healthy Men

Redox Mechanism of Reactive Oxygen Species in Exercise

Effects Of Rose-Hip And Grapeseed Dietary Supplementation On Serum Oxidative Stress Parameters In Dogs Before And After Physical Exercise

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