Antioxidant properties of a new antioxidative peptide from algae protein waste hydrolysate in different oxidation systems

Sheih, I-Chuan; Wu, Tung‐Kung; Fang, Tony J.

doi:10.1016/j.biortech.2009.02.014

Cited by 350 publications

(192 citation statements)

References 32 publications

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“…Sheih et al [37] in a study to obtain biopeptides from seaweed residues obtained compounds of a molecular mass of 1.3 kDa and tested the activity against DPPH and ABTS methods. The authors obtained 50% sequestration of these radicals at low concentrations of approximately 10 μg•mL -1 when compared with synthetic antioxidants.…”

Section: Resultsmentioning

confidence: 99%

Microalgae biopeptides applied in nanofibers for the development of active packaging

et al. 2017

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Section: Resultsmentioning

confidence: 99%

Microalgae biopeptides applied in nanofibers for the development of active packaging

et al. 2017

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“…Thus, many of the prominent microalgae natural sources have targeted for the research and revealed the health effects, for human well-being (Liang et al 2004) as well as for domestic animal applications (Becker 2007). However, there are some potential benefits in addition to the nutritional value of microalgae, including antioxidant (Sheih et al 2009), antitumor (Sheih et al 2010), immunostimulant (Morris et al 2007), antibacterial (Desbois et al 2009), hypocholesterolemic effect (Dvir et al 2009), and angiotensin-converting enzyme inhibitor-I inhibition activity http://e-algae.kr…”

Section: Introductionmentioning

confidence: 99%

In vitro studies of anti-inflammatory and anticancer activities of organic solvent extracts from cultured marine microalgae

Samarakoon¹,

Ko²,

Shah³

et al. 2013

ALGAE

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Marine microalgae are a promising source of organisms that can be cultured and targeted to isolate the broad spectrum of functional metabolites. In this study, two species of cyanobacteria, Chlorella ovalis Butcher and Nannchloropsis oculata Droop, one species of bacillariophyta, Phaeoductylum tricornutum Bohlin, and one species of Dinophyceae, Amphidinium carterae (Hulburt) were cultured and biomasses used to evaluate the proximate comical compositions. Among the determined proximate chemical compositions of the cultured marine microalgae, the highest content of crude proteins and lipids were exhibited in P. tricornutum and A. carterae, respectively. Solvent-solvent partition chromatography was subjected to fractionate each of the cultured species and separated n-hexane, chloroform, ethyl acetate, and aqueous fractions. Nitric oxide production inhibitory level (%) and cytotoxicity effect on lipo-polysaccharide-induced RAW 264.7 macrophages were performed to determine the anti-inflammatory activity. N. oculata hexane and chloroform fractions showed significantly the strongest anti-inflammatory activity at 6.25 µg mL -1 concentration. The cancer cell growth inhibition (%) was determined on three different cell lines including HL-60 (a human promyelocytic leukemia cell line), A549 (a human lung carcinoma cell line), and B16F10 (a mouse melanoma cell line), respectively. Among the extracts, C. ovalis ethyl acetate and A. carterae chloroform fractions suppressed the growth of HL-60 cells significantly at 25 and 50 µg mL -1 concentrations. Thus, the cultured marine microalgae solvent extracts may have potentiality to isolate pharmacologically active metabolites further using advance chromatographic steps. Hence, the cultured marine microalgae can be described as a good candidate for the future therapeutic uses.

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“…On the other hand, the antioxidative peptide Val-Glu-Cys-Ile-Gly-Pro-Asn-ArgPro-Glu-Phe (VECIGPNRPEF) obtained from a well-known microalgae Chlorella vulgaris digested with pepsin exhibited better IC50 inhibition, 0.756 µg/mL (Sheih et al, 2009). Although peptide contained the same number of sequence as FY11, it had more hydrophobic amino acid residues.…”

Section: Antioxidant Activity Of Purified Peptidementioning

confidence: 99%

Antioxidant Activity of Purified Active Peptide Derived from Spirulina platensis Enzymatic Hydrolysates

Safitri

Herawati

Hsu

2017

RJLS

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The aim of this study is to isolate the antioxidative peptide from Spirulina platensis. Peptide was obtained by proteolytic digestion, ultrafiltration, fractionation by RP-HPLC, identified by LC-MS/MS-MASCOT Distiller and measured its antioxidant activity by DPPH (2.2-Diphenyl-1-picrylhydrazyl) assay. Results showed that thermolysin was the most effective enzyme to digest this algae. The active peptide PheSer-Glu-Ser-Ser-Ala-Pro-Glu-Gln-His-Tyr (m/z 1281.51) was identified and synthetized, which exhibited 45.98 ± 1.7% at concentration 128.15 µg/mL. Therefore, S. platensis is indicated as a potential therapeutic source for combating oxidative stress.

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Antioxidant properties of a new antioxidative peptide from algae protein waste hydrolysate in different oxidation systems

Cited by 350 publications

References 32 publications

Microalgae biopeptides applied in nanofibers for the development of active packaging

Microalgae biopeptides applied in nanofibers for the development of active packaging

In vitro studies of anti-inflammatory and anticancer activities of organic solvent extracts from cultured marine microalgae

Antioxidant Activity of Purified Active Peptide Derived from Spirulina platensis Enzymatic Hydrolysates

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