Antioxidants from Pedicularis longiflora var. tubiformis (Klotzsch) P. C. Tsoong

Lan, Yuehui; Chi, Xiaofeng; Zhou, Gengxu; Zhao, X.S.

doi:10.25135/rnp.35.17.08.142

Cited by 11 publications

(7 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The nine two-phase solvent systems listed in Table 3 were selected from literature and tested with the aim to separate the major target compounds in B. globose extract, namely forsythoside B and verbascoside (compounds 12 and 13) [ 15 , 32 , 36 , 37 , 38 , 39 ]. The most suitable KD values to perform the CPC isolation process were obtained with the solvent systems based on ethyl acetate-n-butanol-ethanol-water.…”

Section: Resultsmentioning

confidence: 99%

Polyphenolic Compounds Extracted and Purified from Buddleja Globosa Hope (Buddlejaceae) Leaves Using Natural Deep Eutectic Solvents and Centrifugal Partition Chromatography

et al. 2021

View full text Add to dashboard Cite

Chemical profiling of Buddleja globosa was performed by high-performance liquid chromatography coupled to electrospray ionization (HPLC-DAD-ESI-IT/MS) and quadrupole time-of-flight high-resolution mass spectrometry (HPLC-ESI-QTOF/MS). The identification of 17 main phenolic compounds in B. globosa leaf extracts was achieved. Along with caffeoyl glucoside isomers, caffeoylshikimic acid and several verbascoside derivatives (β-hydroxyverbascoside and β-hydroxyisoverbascoside) were identified. Among flavonoid compounds, the presence of 6-hydroxyluteolin-7-O-glucoside, quercetin-3-O-glucoside, luteolin 7-O-glucoside, apigenin 7-O-glucoside was confirmed. Campneoside I, forsythoside B, lipedoside A and forsythoside A were identified along with verbascoside, isoverbascoside, eukovoside and martynoside. The isolation of two bioactive phenolic compounds verbascoside and forsythoside B from Buddleja globosa (Buddlejaceae) was successfully achieved by centrifugal partition chromatography (CPC). Both compounds were obtained in one-step using optimized CPC methodology with the two-phase solvent system comprising ethyl acetate-n-butanol-ethanol-water (0.25: 0.75: 0.1: 1, v/v). Additionally, eight Natural Deep Eutectic Solvents (NADESs) were tested for the extraction of polyphenols and compared with 80% methanol. The contents of verbascoside and luteolin 7-O-glucoside after extraction with 80% methanol were 26.165 and 3.206 mg/g, respectively. Among the NADESs tested in this study, proline- citric acid (1:1) and choline chloride-1, 2- propanediol (1:2) were the most promising solvents. With these NADES, extraction yields for verbascoside and luteolin 7-O-glucoside were 51.045 and 4.387 mg/g, respectively. Taken together, the results of this study confirm that CPC enabled the fast isolation of bioactive polyphenols from B. globosa. NADESs displayed higher extraction efficiency of phenolic and therefore could be used as an ecofriendly alternative to classic organic solvents.

show abstract

Section: Resultsmentioning

confidence: 99%

Polyphenolic Compounds Extracted and Purified from Buddleja Globosa Hope (Buddlejaceae) Leaves Using Natural Deep Eutectic Solvents and Centrifugal Partition Chromatography

et al. 2021

View full text Add to dashboard Cite

show abstract

“…In fact, Niu et al [164] obtained an IC50 value of 31.16 µM which is higher than ascorbic acid used as positive control (IC50 = 7.81 µM) whereas Georgiev et al [181] an IC50 value of 996 µg/mL which is high in absolute. Indeed, better results were obtained by Lan et al (2018) with an EC50 value of 13.05 µM and by Calis et al [58] with an IC50 value of 61.3 µM.…”

Section: Antioxidant Activitymentioning

confidence: 92%

“…Charami et al [84] also obtained good results expressed as percentages of inhibition which were 88.3% and 89.0% after 20 and 60 min, respectively, at the concentration of 0.1 mM whereas acetyl salicylic, at the same concentration and times, showed a percentage of inhibition of 80.6%. Wang et al [110] obtained a SC50 value of 0.294 mM, Heilmann et al [184] an IC50 value of 0.18 µM and Lan et al [115] an EC50 value of 11.26 µM which are all very potent. The results obtained by Huang et al [148] (2021) are also extremely good given the IC50 value of 72.14 µM which is lower than vitamin C (IC50 = 81.83 µM).…”

Section: Antioxidant Activitymentioning

confidence: 98%

Leucosceptosides A and B: Two Phenyl-ethanoid Glycosides with Important Occurrence and Biological Activities

Frezza¹,

Vita²,

Toniolo³

et al. 2022

Preprint

View full text Add to dashboard Cite

In this review paper, the occurrence in the plant kingdom and the biological activities associated to two specific phenyl-ethanoid glycosides i.e., leucosceptoside A and leucosceptoside B, were shown and discussed. This is the first work ever done on such subject. Analysis of the literature data clearly indicates that leucosceptoside A is much more common in plants and exerts many more biological activities than leucosceptoside B even if this also presents some important elements. All of this was widely discussed in this paper.

show abstract

“…In particular, this compound was found to be the weakest, whereas the most potent was forsythoside B with an IC 50 value of 21 µg/mL. Indeed, Lan et al [ 117 ] obtained an EC 50 value of 13.05 μM, which is comparable to that of ascorbic acid (EC 50 value of 12.29 μM). Lastly, Calis et al [ 60 ] obtained an IC 50 value of 61.3 µM, which is lower than that of dl -α-tocopherol used as a positive control (IC 50 = 75.5 µM); yet there was one phenyl-ethanoid glycosides (myricoside) that is even more potent than this (IC 50 = 46.8 µM).…”

Section: Biological Activitiesmentioning

confidence: 96%

“…Huang et al [ 150 ] obtained an IC 50 value of 72.14 μM, which is lower than vitamin C (IC 50 = 81.83 µM). Lan et al [ 117 ] obtained an EC 50 value of 11.26 μM, which is slightly better than the positive control, ascorbic acid (EC 50 value of 12.29 μM). Indeed, Calis et al [ 60 ] obtained an IC 50 value of 125.4 µM, which is quite higher than that of dl -α-tocopherol, used as a positive control (IC 50 = 75.5 µM).…”

Section: Biological Activitiesmentioning

confidence: 98%

Leucosceptosides A and B: Two Phenyl-Ethanoid Glycosides with Important Occurrence and Biological Activities

et al. 2022

View full text Add to dashboard Cite

In this review paper, the occurrence in the plant kingdom, the chemophenetic value and the biological activities associated with two specific phenyl-ethanoid glycosides, i.e., leucosceptoside A and leucosceptoside B, were reported. This is the first work ever conducted on such a subject. Analysis of the literature data clearly led to three important conclusions: leucosceptoside A is much more common in plants than leucosceptoside B; leucosceptoside A exerts more biological activities than leucosceptoside B even if nothing can be generally concluded about which one is actually the most potent; neither of these compounds can be used as a chemophenetic marker. These three aspects and more are discussed in more depth in this work.

show abstract

Antioxidants from Pedicularis longiflora var. tubiformis (Klotzsch) P. C. Tsoong

Cited by 11 publications

References 14 publications

Polyphenolic Compounds Extracted and Purified from Buddleja Globosa Hope (Buddlejaceae) Leaves Using Natural Deep Eutectic Solvents and Centrifugal Partition Chromatography

Polyphenolic Compounds Extracted and Purified from Buddleja Globosa Hope (Buddlejaceae) Leaves Using Natural Deep Eutectic Solvents and Centrifugal Partition Chromatography

Leucosceptosides A and B: Two Phenyl-ethanoid Glycosides with Important Occurrence and Biological Activities

Leucosceptosides A and B: Two Phenyl-Ethanoid Glycosides with Important Occurrence and Biological Activities

Contact Info

Product

Resources

About