Antioxidative effect of folate–modified chitosan nanoparticles

Chakraborty, Subhankari Prasad; Mahapatra, Santanu Kar; Sahu, Sumanta Kumar; Pramanik, Panchanan; Roy, Somenath

doi:10.1016/s2221-1691(11)60064-6

Cited by 36 publications

(15 citation statements)

References 33 publications

(40 reference statements)

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“…Eugenol (4-allyl-2-methoxyphenol) is a naturally phenolic compound widely used in food, pharmaceutical, cosmetics and active packaging applications, due to its effective antimicrobial and antioxidant properties [18,19,20,21]. However, most plant-derived bioactive compounds, including eugenol, are highly volatile, unstable, and sensitive to oxygen, light and heat during processing, utilization and storage.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Encapsulation of bis-eugenol in a Mesoporous Solid Material: Enhancement of the Antioxidant Activity of a Natural Compound from Clove Oil

Guntero

Ferretti

Mancini

et al. 2018

CSIJ

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In the present work, microwave extraction conditions to recover high eugenol content in the crude extract from clove were investigated. The effect of factors like temperature, stirring, time, liquid: Solid ratio and solutions of solvent were evaluated with Taguchi's method. The eugenol content was determined by gas chromatography. From the isolated eugenol, the bis-phenol was synthesized by the dimerization of eugenol. The encapsulation of bis-eugenol on the mesoporous silica was carried out by a microwave assisted process. Previously, mesoporous silica SBA-15 was prepared by hydrothermal synthesis using Pluronic P123 triblock copolymer as a surfactant. The bis-eugenol

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Section: Introductionmentioning

confidence: 99%

Synthesis and Encapsulation of bis-eugenol in a Mesoporous Solid Material: Enhancement of the Antioxidant Activity of a Natural Compound from Clove Oil

Guntero

Ferretti

Mancini

et al. 2018

CSIJ

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“…In our previous laboratory report, we synthesized CMC-EDBE-FA nanoparticle based on carboxy methyl chitosan tagged with folic acid by covalently linkage through 2, 2' (ethylenedioxy) bis-(ethylamine), vancomycin was loaded onto it called "nanoconjugated vancomycin" and observe it's in vitro bactericidal activity against S. aureus [18] . In our recent laboratory report, we observed that CMC-EDBE-FA is non-toxic [19] . The present study was aimed to test the survival of S. aureus inside lymphocyte that contributes to the pathogenesis of infection; and possible anti-inflammatory and antioxidative effect of nanoconjugated vancomycin against in vivo S. aureus infection in a dose and duration dependent manner.…”

Section: Introductionmentioning

confidence: 78%

Nitric oxide mediated Staphylococcus aureus pathogenesis and protective role of nanoconjugated vancomycin

Chakraborty¹,

Mahapatra²,

Sahu³

et al. 2011

Asian Pacific Journal of Tropical Biomedicine

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“…Chakraborty et al [40] have reported that nicotine induces free radical generation such as superoxide anion and hydrogen peroxide that causes oxidative stress within the cells. Reports say that administration of curcumin significantly lowers the biochemical marker enzymes, inhibits lipid peroxidation [41] and enhances the antioxidant status [42].…”

Section: Discussionmentioning

confidence: 99%

Protective Role of Raw-Turmeric Rhizomes Against Nicotine-Induced Complications of Beedi (Indian Cigarette) Workers

Chattopadhyay¹

2015

Pharm Anal Acta

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Introduction: The unscientific process of beedi (Indian smoking element) production under constant exposure of nicotine dust in India induces serious health disorders to the workers. Beedi produces more tar in smoke than cigarette due to lack of any filtering process. Sometimes active consumption of beedi and other tobacco products makes the users more vulnerable to cancer, respiratory diseases and cardiovascular disorders etc.Objective: The present study was designed to observe the protective effects of raw turmeric rhizomes on health conditions of the beedi workers who were exposed to nicotine dust for 8-10 hours daily for a long duration.Methods: General health checkup, blood glucose levels, lipid profiles and the hemogram profiles etc. of the workers from two beedi factories (Canning of South 24 Parganas District and Bankura of Bankura District, both in West Bengal, India) were conducted before and after the consumption of laboratory processed raw turmeric rhizomes (80 mg/kg body weight/day by chewing) for 8 weeks. Blood samples (5 ml) were collected from all the workers before and after the completion of the study and analyzed for estimation of different parameters. Results:The results showed significant improvement in the general health conditions of the factory workers who consumed raw-turmeric rhizomes. Significant improvement of blood pressure, blood glucose levels and lipid profiles and also improvement of creatinine, serum protein and SGOT/SGPT levels of the treated volunteers were noted. The results also showed improvement in the enzymes levels of SOD, GSH and GP X in the serum of rhizomes consumed workers. Conclusion:It is concluded that turmeric rhizomes are effective in the amelioration of nicotine-induced complications. It would be a better therapeutic supplement for the improvement of health for the workers who are compelled to work under nicotinic dust environment for a long time.

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Antioxidative effect of folate–modified chitosan nanoparticles

Cited by 36 publications

References 33 publications

Synthesis and Encapsulation of bis-eugenol in a Mesoporous Solid Material: Enhancement of the Antioxidant Activity of a Natural Compound from Clove Oil

Synthesis and Encapsulation of bis-eugenol in a Mesoporous Solid Material: Enhancement of the Antioxidant Activity of a Natural Compound from Clove Oil

Nitric oxide mediated Staphylococcus aureus pathogenesis and protective role of nanoconjugated vancomycin

Protective Role of Raw-Turmeric Rhizomes Against Nicotine-Induced Complications of Beedi (Indian Cigarette) Workers

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