Antithyroid antibodies may predict serum beta HCG levels and biochemical pregnancy losses in euthyroid women with IVF single embryo transfer

Güngör, Kağan; Güngör, Nur Dokuzeylül

doi:10.1080/09513590.2020.1830968

Cited by 9 publications

(11 citation statements)

References 19 publications

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“…Iravani et al (17) and Lata et al (18) showed that TAI disease may cause recurrent miscarriages. Somewhat, there are still suspicions about the correlation between recurrent miscarriages and TAI (19,20).…”

Section: Resultsmentioning

confidence: 99%

The findings about relationship between autoimmune thyroid disease and first-trimester aneuploidy results

GÜRKAN

ÖZTÜRK

2022

Journal of Health Sciences and Medicine

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Aim: The aim of this study was to investigate the relationship between thyroid autoantibody and first-trimester aneuploidy results. Thyroid autoimmunity (TAI) is the most common autoimmune disorder. Patients with TAI are usually euthyroid. Thyroid peroxidase (TPO-Ab) in patients with or without thyroid dysfunction is associated with infertility, recurrent embryo implantation failure, and early pregnancy loss. The impact of TPO-Ab on first-trimester aneuploidy test results needs to be studied. Material and Method: This retrospective case-control study was conducted between December 2019 and May 2022. Patients with thyroid autoantibody positivity (n=112) were included in the study as the case group. The control group was selected from age and body mass index (BMI)-matched patients (n=130). Nuchal translucency (NT), crown rump length (CRL), pregnancy-associated plasma protein A (PAPP-A) and free beta subunit of human chorionic gonadotropin (β-hCG)) values were compared between the two groups. Results: This study included two hundred forty two age-matched (29.86±4.51) and BMI-matched (23.96±2.34) women. There was no statistically significant difference between groups in terms of free thyroxine (FT4), PAPP-A and free β-hCG (p>0.05). NT as a marker for major chromosomal defects and CRL were comparable in case and control groups (p>0.05). Conclusion: There is no statistically significant relationship between thyroid autoimmune diseases and the first-trimester aneuploidy results.

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Section: Resultsmentioning

confidence: 99%

The findings about relationship between autoimmune thyroid disease and first-trimester aneuploidy results

GÜRKAN

ÖZTÜRK

2022

Journal of Health Sciences and Medicine

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“…The American College of Radiology determines the ultrasonographic character of thyroid nodules as TIRADS (Thyroid Imaging Reporting and Data System). Based on the sonographic results on the determination of nodules, this system needs to be analyzed for potential malignancy [3]. Internal composition, echogenicity, margins, echogenic foci, and nodule shape are essential for the scoring criteria.…”

Section: Tirads Systemmentioning

confidence: 99%

“…The steady worldwide increase in the incidence of thyroid cancers (TCs) would be insufficient to explain it with an increase in disease frequency, as this has contributed to the lack of diagnostic methods (2). When diagnosed early and well-differentiated pathologically, the prognosis of easily treated TCs is perfect (3). Especially the long-term survival rate of most stage-1 approaches is excellent at 100% (4).…”

Section: Introductionmentioning

confidence: 99%

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Efficacy analysis between ultrasound and cytology criteria in the differentiation of malignant and benign thyroid nodules: TIRADS versus BETHESDA

DENİZ>

SARI

ÖZTURK

2023

Journal of Health Sciences and Medicine

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Aim: Thyroid nodules (TNs) are abnormal masses of different structures and sizes to be detected promptly. The present study aimed to investigate the relationship between Bethesda and TIRADS and their diagnostic efficiency in histopathologically diagnosed malign TNs. Material and Method: 475 patients with TNs enrolled in this cross-sectional research. Laboratory parameters and clinical thyroid history were obtained from the automation system and analyzed retrospectively. They have been staged according to TIRADS, and the neck is evaluated in suspicious lymph nodes. FNAB results are then tracked for Bethesda staging. Results: TIRADS showed a good sensitivity at the rate of 74.5% and average specificity at 68.1% for TNs. Bethesda had a higher sensitivity at 80.1% and 95.2% specificity rates. The positive predictive (98.1 vs. 88.2) and negative predictive (13 vs. 23.6) values were higher for Bethesda than TIRADS. The diagnostic accuracy for Bethesda was 79%. According to the ROC, Bethesda had a more expansive area under curve (0.81) than TIRADS (0.63). FNAC was a better diagnostic method than ultrasonography in evaluating thyroid nodules (p

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“…The frequency of autoimmune thyroid disease with low anti-TPO and high anti-TG levels is around 5%. Anti-TPO and anti-TG are positive at a rate of 95-100% in Hashimoto's thyroiditis (10).…”

Section: Introductionmentioning

confidence: 98%

Is Hashimoto Thyroiditis a risk factor in male infertility?

ÖNAL¹,

AĞAR²,

ERŞAHİN³

et al. 2022

J Exp Clin Med

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Hashimoto's thyroiditis is known as thyroid dysfunction and is one of the most common endocrine diseases worldwide. This study seeks to investigate thyroid dysfunction in the male reproductive system. Normal thyroid function is crucial for male reproduction. Semen quality parameters are among the most critical factors affecting male fertility. The main aim of this research was to investigate the effect of thyroid dysfunction on semen quality parameters such as sperm motility, number, and morphology. This cross-sectional retrospective case-control study was conducted between December 2021 and May 2022 in Bahcesehir University Göztepe Medicalpark Hospital Invitro Fertilization center. Patients with Hashimoto's thyroiditis (n=52) were included in the study as the case group. The control group was selected from age and body mass index (BMI)-matched patients who underwent semen analysis (n=57). The participants' age and BMI were 30.90±4.45 and 24.49±1.46, respectively. When we evaluated semen analysis results, we found the number of sperms (p<0.001), motility (p<0.01), and morphology (p<0.001) were significantly better in the controls than in the patients with Hashimoto's thyroiditis. Oligozoospermia, asthenozoospermia, and oligoasthenozoospermia as sperm abnormalities were observed in patients with Hashimoto's thyroiditis. Hashimoto's thyroiditis has a negative effect on semen quality parameters such as sperm motility, number, and morphology. Evaluation of infertile men is recommended in terms of thyroid dysfunction.

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Antithyroid antibodies may predict serum beta HCG levels and biochemical pregnancy losses in euthyroid women with IVF single embryo transfer

Cited by 9 publications

References 19 publications

The findings about relationship between autoimmune thyroid disease and first-trimester aneuploidy results

The findings about relationship between autoimmune thyroid disease and first-trimester aneuploidy results

Efficacy analysis between ultrasound and cytology criteria in the differentiation of malignant and benign thyroid nodules: TIRADS versus BETHESDA

Is Hashimoto Thyroiditis a risk factor in male infertility?

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