2002
DOI: 10.1046/j.1365-2133.2002.04979.x
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Application of imiquimod by suppositories (anal tampons) efficiently prevents recurrences after ablation of anal canal condyloma

Abstract: These data suggest that imiquimod anal tampons may represent a new therapeutic option to prevent recurrences of ACC following ablative surgery.

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Cited by 75 publications
(58 citation statements)
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“…Our findings are in contrast to those of Kaspari et al, 5 who did not see recurrences in 10 HIV-negative patients within a mean follow-up time of 9 months. The poorer outcome in our patients can be explained on the one hand by the HIV-associated immunosuppression probably leading to a new increase in HPV-11 DNA load (patient 6).…”
Section: Resultscontrasting
confidence: 85%
“…Our findings are in contrast to those of Kaspari et al, 5 who did not see recurrences in 10 HIV-negative patients within a mean follow-up time of 9 months. The poorer outcome in our patients can be explained on the one hand by the HIV-associated immunosuppression probably leading to a new increase in HPV-11 DNA load (patient 6).…”
Section: Resultscontrasting
confidence: 85%
“…In addition, it has been reported that there are adverse side effects resulting from the treatments. Patients most frequently complained of itch and to a lesser extent of a burning sensation, but rarely of pain (19)(20)(21)(22).…”
mentioning
confidence: 99%
“…Este tratamento já é reconhecido como uma opção para lesões anogenitais causadas pelo HPV, e tem sido usado com êxito no tratamento de lesões pré-malignas e malignas da pele como Doença de Bowen e ceratose actínica. (18) Os efeitos colaterais são mínimos e não exigem interrupção do tratamento, sendo relatados queimação local, eritema e ulcerações cutâneas superficiais. (6,18) Um fator limitante do uso mais amplo, em nosso meio, é que se trata de uma medicação dispendiosa.…”
Section: Discussionunclassified
“…(18) Os efeitos colaterais são mínimos e não exigem interrupção do tratamento, sendo relatados queimação local, eritema e ulcerações cutâneas superficiais. (6,18) Um fator limitante do uso mais amplo, em nosso meio, é que se trata de uma medicação dispendiosa.…”
Section: Discussionunclassified