Application of Nanotechnology in COVID-19 Infection: Findings and Limitations

Shehu, Ibrahim Aminu; Musa, Muhammad Kabir; DATTA, APARNA; Verma, Amita

doi:10.3390/jnt3040014

Cited by 3 publications

(3 citation statements)

References 224 publications

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“…[63] In the earlier review articles, for instance, discussions of synthetic methods, physical characteristics, electronic and material synthesis, sensor design, and personal health monitoring were covered, but the majority of novel fabrication methods were not mentioned. [64][65][66][67][68][69][70][71][72][73][74][75] The review article by Narita, Fumio, et al [76] explained how piezoelectric sensors using materials like BaTiO 3 , PbTiO 3 , and ZnO were used for COVID-19 and other virus detection. Nikhil Bhalla and colleagues study biochemical sensors and analytical tools to critically examine the barriers preventing the use of advanced sensing technologies in pandemic diseases.…”

Section: Nanomaterials For Electronic Virus Detectionmentioning

confidence: 99%

“…In the earlier review articles, for instance, discussions of synthetic methods, physical characteristics, electronic and material synthesis, sensor design, and personal health monitoring were covered, but the majority of novel fabrication methods were not mentioned. [ 64–75 ] The review article by Narita, Fumio, et al. [ 76 ] explained how piezoelectric sensors using materials like BaTiO 3 , PbTiO 3 , and ZnO were used for COVID‐19 and other virus detection.…”

Section: Introductionmentioning

confidence: 99%

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Recent Advances in Nanomaterials‐Based FETs for SARS‐CoV‐2 (COVID‐19 Virus) Diagnosis

Aftab

Iqbal

Hussain

et al. 2023

Adv Funct Materials

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The emergence of infectious diseases that are quickly spreading, like the coronavirus (COVID-19), necessitates the development of efficient biosensors that can quickly detect and identify pathogens. It is essential to create sensitive virus detection methods in order to stop a virus from spreading throughout the world. It is determined that field-effect transistors (FETs) made of nanomaterials are potential candidates for rapid virus identification due to how easily the electronic transport characteristics of such an atomically thin nanomaterial can be affected by perturbations. Various FETs in this review article are investigated that are based on nanoparticles, carbon nanotubes (CNT), graphene, graphene-oxide, and semiconducting transition metal dichalcogenides (TMDs) WSe 2 in order to show that they are promising biosensors in regards to quickly and precisely detect COVID-19. The conjugation of nanomaterials with proteins enables the direct delivery of antiviral agents to the host cells. This method also minimizes the off-target effects and enables the targeted interactions. This mechanism has produced encouraging results in regards to sensing or treating COVID-19. The high surface area and extremely small size of nanomaterials make them crucial in regards to the development of new detection methods. The point-of-care test method of detection is quick, simple, and user-friendly, and it only requires a small amount of a patient's blood. It does not require a laboratory or trained professionals. This overview of the current research that is conducted on nanomaterials will prove to be useful in the process of formulating strategies for the diagnosis, treatment, and vaccination of viruses in opinion. Finally, the conclusion of this review provides a summary of the current challenges and the future prospects.

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Section: Nanomaterials For Electronic Virus Detectionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Recent Advances in Nanomaterials‐Based FETs for SARS‐CoV‐2 (COVID‐19 Virus) Diagnosis

Aftab

Iqbal

Hussain

et al. 2023

Adv Funct Materials

View full text Add to dashboard Cite

show abstract

“…Swab the nose or the throat, or spit. [22] Time required to observe the results:-The average wait time is between 2 and 3 days.…”

Section: Rt-pcr Rapid Antigen Testing Kits Referencesmentioning

confidence: 99%

A perspective on the effectiveness of SARS-Cov-2 rapid testing kits

Kaur,

Kumar Rangra

2023

Pharmaspire

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Patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) are generally diagnosed by rapid antigen test (RAT) and reverse transcription-polymerase chain reaction (RT-PCR) tests. However, there is a conflict that the RT-PCR test is more effective than the RAT. The primary objective of this perspective is to compare and outline the effectiveness of SARS-CoV-2 rapid testing kits available in the market with RT-PCR tests. Recently published systematic reviews and meta-analysis reports containing comparative studies of RAT and RT-PCR were selected. The analysis results revealed that RAT kits provide remarkable specificity and sensitivity in the early stages of infection, particularly when the viral load is huge, compared to RT-PCR. In addition, a trustworthy substitute for nasopharyngeal sampling is the use of nasal specimens for antigen detection, which are patient-friendly and somewhat sensitive. RAT could be beneficial in the combat against the COVID-19 pandemic, but it has to be combined with appropriate monitoring of results that come back negative.

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Nanostructures for the Prevention, Diagnosis, and Treatment of COVID‐19: A Review

Tavakoli,

Ranjbar,

Tackallou

et al. 2024

Part & Part Syst Charact

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Viral infections are a significant cause of death globally, resulting in substantial ethical, social, and economic costs. In recent years, the world has experienced the worst epidemic of the current millennium, caused by the Coronavirus 2019, a severe acute respiratory syndrome. This infection can cause severe complications in various organs, such as the stomach, heart, liver, kidney, and brain. Antimicrobial drugs or vaccines can be a practical approach to combating these pathogens. However, there are drug‐resistant or emerging infections that do not have effective drugs or vaccines. Therefore, it is necessary to explore new approaches for early diagnosis, prevention, and effective therapies. So, nanomaterials are widely considered due to their unique properties. This review employs a practical approach to elucidate the role of nanostructures against COVID‐19. Also, the effects and benefits of various types of nanostructures are discussed that have been used to diagnose, prevent, and treat COVID‐19 in recent years. Furthermore, by evaluating different nanostructures, the utilization of biocompatible nanoparticles consisting of selenium and chitosan derivatives is suggested as a promising candidate for industrial use in the fight against COVID‐19. Ultimately, this study can offer insight into the potential applications of nanomaterials in combating emerging microbial infections.

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Application of Nanotechnology in COVID-19 Infection: Findings and Limitations

Cited by 3 publications

References 224 publications

Recent Advances in Nanomaterials‐Based FETs for SARS‐CoV‐2 (COVID‐19 Virus) Diagnosis

Recent Advances in Nanomaterials‐Based FETs for SARS‐CoV‐2 (COVID‐19 Virus) Diagnosis

A perspective on the effectiveness of SARS-Cov-2 rapid testing kits

Nanostructures for the Prevention, Diagnosis, and Treatment of COVID‐19: A Review

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