Application of Plasma Sprayed Zirconia Coating in Dental Implant: Study in Implant

Abstract

The aim was to investigate the osseointegration of a novel coating-plasma-sprayed nanostructured zirconia (NSZ) in dental implant. Nanostructured zirconia coating on non-thread titanium implant was prepared by plasma spraying, the implant surface morphology, surface roughness and wettability were measured. In vivo, nanostructured zirconia-coated implants were inserted in rabbit tibia and animals were respectively sacrificed at 2, 4, 8 and 12 weeks after implantation. The bond strength between implant and bone was measured by removal torque (RTQ) test. The osseointegration was observed by scanning electron microscopy (SEM), micro computed tomography (Micro CT) and histological analyses. Quantified parameters were calculated, including removal torque, Bone Volume to Tissue Volume (BV/TV), Trabecular Thickness (Tb. Th), Trabecular Number (Tb. N), Trabecular Separation/Spacing (Tb. Sp), and Bone-Implant contact (BIC) percentage. The statistical differences were detected by two-tail Mann-Whitney U test (SPSS 20.0). The surface roughness (1.58µm) and wettability (54.61°) of nanostructured zirconia coated implant was more suitable than those of titanium implant (0.598µm and 74.38°) for osseointegration and hierarchical surface morphology could be seen on zirconia coating. The histological analyses showed that zirconia coated implant induced earlier and more condensed bone formation than titanium implant at 2 and 4 weeks. Quantified parameters showed the significant differences between these two groups at early healing period, but the differences between these two groups decreased with the increase of healing period. All these results demonstrated that plasma sprayed zirconia coated implant induced better bone formation than titanium implant at early stage.

Sdccag3 Promotes Implant Osseointegration during Experimental Hyperlipidemia

“…Long noncoding RNAs (lncRNAs), which are important ncRNAs more than 200 nucleotides (nt) in length, have been shown to modulate posttranscriptional events during gene expression (Yoon et al 2012; Kopp and Mendell 2018; Tang et al 2019). MicroRNAs (miRNAs), which constitute another major type of ncRNA, have been shown to regulate osteoblast differentiation (Zhou et al 2016; Huang, Wang, Li, Huang, et al 2018; Zheng et al 2019) and implant osseointegration (Liu et al 2018).…”

The impact of surface treatment in 3-dimensional printed implants for early osseointegration: a comparison study of three different surfaces

“…The tibial model in rabbit was used to evaluate the biologic responses of 3D-printed, 3D-printed with SLA and 3D-printed with TIPS implants. The rabbit tibial model was used because the aim of this study was to investigate the biologic performance of 3D-printed implants without surface treatment, with SLA, and with TIPS surface treatment in the absence of mechanical loading according to the previous studies 26 , 27 . Nine rabbits each were assigned to the 2-week group, 4-week group, and 12-week group, and a total of 27 rabbits were involved in this study.…”

Peri̇odontoloji̇de Deney Hayvani Ve Hastalik Modelleri̇

“…Ġmplant uygulamaları, osseointegrasyon, primer stabilite gibi faktörlerle model uygunluğu nedeniyle günümüzde sıklıkla tavşanlarda yapılmaktadır. [42][43][44] Feretler özellikle diş taşı üzerinde yapılan çalışmalarda yüksek başarılı sonuçlar vermektedir. Diş taşı çalışmalarındaki tutarlılığı köpekler kadar yüksek olmasının yanı sıra üretim zamanlarının çok daha kısa olması, etik ve maliyet açısından uygunluğu olası bir diş taşı çalışması için feretleri en uygun çalışma modeli olarak işaret etmektedir.…”

“…51 Ülkemizde domuzlar ile çalışılabilecek deney hayvanları laboratuarı oldukça kısıtlı olması nedeniyle sıklıkla implant konulu çalışmalarda tavşanlar tercih edilmektedir. Tavşanların femur veya tibiasına yerleştirilen gerçek boyda implantlarda yüzey özellikleri 42,52 , primer stabilite 53 , osseointegrasyon 54 ,implant başarısı 55,56 ve sistemik koşulların etkisi gibi birçok konu incelenebilmektedir. 57 Ayrıca ileri cerrahi tekniklerin pratiğinde hayvan modelleri kulanılmaktadır.…”