Application of rifaximin for selective digestive decontamination during experimental severe acute pancreatitis

Rotar, Oleksandr; Rotаr, Vasyl; Arkhelyuk, Oleksandr; Rotar, r

doi:10.1016/j.pan.2014.05.582

Cited by 2 publications

(1 citation statement)

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“…In the commercialization of food, high encapsulation rate also means lower transportation cost of functional factors [20]. The increasing peptide content makes EE increase continuously, in accordance with previous studies [21,22]. The electrostatic interaction between polypeptide and CS-TPP carrier may lead to high EE.…”

Section: Determination Of Ee and Ecsupporting

confidence: 85%

Chitosan/tripolyphosphate nanoparticle as elastase inhibitory peptide carrier: characterization and its in vitro release study

et al. 2023

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This study was aimed at the preparation and evaluation of walnut meal derived elastase inhibitory peptide (FFVPF) loaded in chitosan-tripolyphosphate (CS-TPP) nanoparticles (NPs). It was shown that the maximum encapsulation e ciency of FFVPF could reach 94.58 ± 0.23%. TEM microphotographs, polydispersity index and zeta-sizer reports indicated that FFVPF-loaded CS-TPP NPs were in nanometric range and were spherical, discrete and uniform in size with PDI less than 0.3. FTIR analysis indicated that the peptides interacted with CS-TPP NPs through strong hydrogen bonds and electrostatic interactions.And the CS-TPP FFVPF NPs showed better stability with heating treatment, pH treatment, or photochemical treatment. Moreover, the in vitro release pro le of peptides was identi ed. The release rate of encapsulated FFVPF was released explosively to 77.22 ± 2.21% and gradually slowed down. These ndings highlighted the prospect of CS-TPP NPs as an oral delivery system, and the application of peptides within food and pharmaceutical products.

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Section: Determination Of Ee and Ecsupporting

confidence: 85%

Chitosan/tripolyphosphate nanoparticle as elastase inhibitory peptide carrier: characterization and its in vitro release study

et al. 2023

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Chitosan/tripolyphosphate nanoparticle as elastase inhibitory peptide carrier: Characterization and its in vitro release study

Xiong

Cheng

Wang

et al. 2022

Preprint

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This study was aimed at the preparation and evaluation of walnut meal derived elastase inhibitory peptide (FFVPF) loaded in chitosan-tripolyphosphate (CS-TPP) nanoparticles (NPs). It was shown that the maximum encapsulation efficiency of FFVPF could reach 94.58 ± 0.23%. TEM microphotographs, polydispersity index and zeta-sizer reports indicated that FFVPF-loaded CS-TPP NPs were in nanometric range and were spherical, discrete and uniform in size with PDI less than 0.3. FTIR analysis indicated that the peptides interacted with CS-TPP NPs through strong hydrogen bonds and electrostatic interactions. And the CS-TPP FFVPF NPs showed better stability with heating treatment, pH treatment, or photochemical treatment. Moreover, the in vitro release profile of peptides was identified. The release rate of encapsulated FFVPF was released explosively to 77.22 ± 2.21% and gradually slowed down. These findings highlighted the prospect of CS-TPP NPs as an oral delivery system, and the application of peptides within food and pharmaceutical products.

show abstract

Application of rifaximin for selective digestive decontamination during experimental severe acute pancreatitis

Cited by 2 publications

References 0 publications

Chitosan/tripolyphosphate nanoparticle as elastase inhibitory peptide carrier: characterization and its in vitro release study

Chitosan/tripolyphosphate nanoparticle as elastase inhibitory peptide carrier: characterization and its in vitro release study

Chitosan/tripolyphosphate nanoparticle as elastase inhibitory peptide carrier: Characterization and its in vitro release study

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