Applications of Cytosorb in clinical practice

Kutnik, Paweł; Borys, Michał

doi:10.26444/jpccr/112882

Cited by 3 publications

(5 citation statements)

References 39 publications

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“…-Treatment plasmapheresis by centrifugation. hemoperfuSion 26,[37][38][39] -Hemoperfusion to remove medium molecules, drugs and toxins. -Hemoperfusion to remove endotoxins.…”

Section: Modalitiesmentioning

confidence: 99%

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Acute kidney injury and renal replacement therapy: terminology standardization

et al. 2022

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The Department of Acute Kidney Injury (IRA) of the Brazilian Society of Nephrology prepared this document for the purpose of standardizing AKI terminology and dialysis modalities in the Portuguese language for Brazil. Several terms with similar meanings have been used in AKI and its dialysis modalities, causing confusion and disparities among patients, nephrologists, health institutions, private care companies, insurance companies and government entities. These disparities can impact medical care, hospital organization and care, as well as the funding and reimbursement of AKI-related procedures. Thus, consensual nomenclature and definitions were developed, including the definitions of AKI, acute kidney disease (AKD) and chronic kidney disease (CKD). Additionally, we addressed all dialysis modalities and extracorporeal procedures related to AKI, currently approved and available in the country. The Brazilian Society of Nephrology hopes that this Consensus can standardize the terminology and provide technical support to all involved in AKI care in Brazil.

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“…-Treatment plasmapheresis by centrifugation. hemoperfuSion 26,[37][38][39] -Hemoperfusion to remove medium molecules, drugs and toxins. -Hemoperfusion to remove endotoxins.…”

Section: Modalitiesmentioning

confidence: 99%

“…extracorporeal artificial kidney Support hemoperfuSion 26,[37][38][39] heMoPerFusion For reMoval oF MediuM Molecules (0.5 -58 Kda), drugs and toxins -Duration: 2-24 hours.…”

Section: Modalitiesmentioning

confidence: 99%

Acute kidney injury and renal replacement therapy: terminology standardization

et al. 2022

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“…hemoperfuSão 26,[37][38][39] -Hemoperfusão para remoção de moléculas médias, fármacos e toxinas. -Hemoperfusão para remoção de endotoxinas.…”

Section: Hemodiálise Prolongadaunclassified

“…- hemoperfuSão 26,[37][38][39] HeMoperFusão para reMoção de Moléculas Médias (0,5 -58 kda), FárMacos e toxinas -Duração: 2-24 horas.…”

Section: Suporte Renal Artificial Peritonealunclassified

Injúria renal aguda e métodos de suporte: padronização da nomenclatura

et al. 2022

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Resumo O Departamento de Injúria Renal Aguda (IRA) da Sociedade Brasileira de Nefrologia elaborou o presente documento para fins de padronização da terminologia em IRA e modalidades dialíticas na língua portuguesa para o Brasil. Diversos termos com significados semelhantes têm sido empregados em IRA e suas modalidades dialíticas, causando confusão e disparidades entre pacientes, nefrologistas, instituições de saúde, empresas privadas de assistência, seguradoras e entidades governamentais. Essas disparidades podem impactar a assistência médica, a organização e o atendimento hospitalares, assim como o financiamento e reembolso dos procedimentos relacionados com a IRA. Assim, nomenclatura e definições consensuais foram elaboradas, incluindo-se as definições de IRA, doença renal aguda (DRA) e doença renal crônica (DRC). Adicionalmente, todas as modalidades dialíticas e os procedimentos extracorpóreos relacionados a IRA, atualmente aprovados e disponíveis no país, foram abordados. A Sociedade Brasileira de Nefrologia espera que este Consenso possa padronizar a nomenclatura e prover suporte técnico para todos os atores envolvidos na assistência à IRA no Brasil.

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“…Other areas of application that are currently being intensively researched include polytrauma and severe burns, acute pancreatitis, different types of liver failure, and severe cardiogenic shock. 17 Starting the therapy at the right time: recent trials indicate better clinical outcomes if the therapy is initiated within 24 hours of clinical diagnosis of sepsis. 20,21 A CytoSorb® scoring system was proposed (Fig.…”

Section: Cytosorb®: Field Of Applicationmentioning

confidence: 99%

Hemoadsorption (CytoSorb®) in Management of Cytokine Storm and Implication in COVID-19 Pandemic

Prasad¹,

Mishra²,

Maheshwarappa³

et al. 2022

Journal of Acute Care

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Cytokines are a varied group of proteins released by our immune system and play an essential role in normal immune responses. There are different cytokines, including chemokines, interferons, interleukins (IL), lymphokines, and tumor necrosis factor (TNF). The primary functions of cytokines include inflammatory response, angiogenesis, down and upregulation of receptors, and control of cell differentiation. 5 However, in response to a severe immune reaction, many cytokines are released into the bloodstream. This sudden increase in cytokines is known as a cytokine storm. 5 It can be severe or IntroductIonAn estimated 48.9 million incident cases of sepsis were registered in 2017, with sepsis accounting for 19.7% of all global deaths. India contributed 11.3 million of these sepsis cases in 2017. Sepsis-related age-standardized incidence is 992/100,000 population. 1 The mortality rate with severe sepsis is about 30% in the Indian population. With low and mid-socioeconomic countries contributing to the doubling of sepsis globally in the last decade, a need for early diagnosis and treatment needs no emphasis. Newer insights into the pathophysiology of sepsis revolve around the imbalance in inflammatory mediators. 2 Cytokines act as mediators that are pivotal in the pathophysiology of sepsis. 3 Therapy to reduce, block, and filter cytokines continue to lure intensive care physicians around the globe. The present SARS-CoV-2 infection has generated interest for cytokine therapies in its management. 4 MaterIals a n d MethodsWe performed a literature review on the use of cytokine hemoadsorption therapies in Indian patients and looked at the clinical implications of such therapies in the current COVID-19 pandemic. An extensive literature search was done for keywords "hemoadsorption" and "CytoSorb®" using PubMed and Google Scholar search engines. All manuscripts with patients at Indian centers enrolled. We extend our review of cytokine storm in COVID-19 and the utility of CytoSorb® as an adjuvant in the management of septic shock in COVID-19.

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Applications of Cytosorb in clinical practice

Cited by 3 publications

References 39 publications

Acute kidney injury and renal replacement therapy: terminology standardization

Acute kidney injury and renal replacement therapy: terminology standardization

Injúria renal aguda e métodos de suporte: padronização da nomenclatura

Hemoadsorption (CytoSorb®) in Management of Cytokine Storm and Implication in COVID-19 Pandemic

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