Appraisal of the remineralizing potential of child formula dentifrices on primary teeth: An i n vitropH cycling model

Abstract

Aim:To evaluate the remineralizing potential of child formula dentifrices on primary teeth using an in vitro 7 days pH cycling model.Materials and Methods:Twenty-one primary teeth were placed in demineralizing solution for 96 h to produce artificial carious lesions; then cut longitudinally into 100–150 μm thick sections and randomly assigned to three groups. Sections in Group A were treated with dentifrice containing 458 ppm monofluorophosphate (MFP) and sections in Group B with 500 ppm sodium fluoride (NaF). Group C sections were treated with a nonfluoridated dentifrice.Results:Group A (458 ppm MFP) and Group B (500 ppm NaF) showed significant decrease in lesion depth, whereas Group C (non F) showed a significant increase in depth (P ≤ 0.05, paired t-test).Conclusion:Though dentifrices containing 458 ppm MFP and 500 ppm NaF demonstrated remineralization of carious lesions, it was not complete. Therefore, it is also important to emphasize on other preventive methods in the prevention and/or reversal of carious lesions.

Effects of Fluoride on Two Chemical Models of Enamel Demineralization

“…Lactic acid and acetate acid are the common acid-buffer solutions used in chemical models to create demineralized lesions or artificial caries for cariology research [ 11 , 12 , 13 ]. Hence, they were chosen in this study.…”

The Efficacy of Non-fluoridated Toothpastes on Artificial Enamel Caries in Primary Teeth

“…[ 15 ] A 7-day pH-cycling was chosen because it was found to be the most appropriate period for the study in primary teeth as the enamel lesions could appear in 7 days and become dentin lesions afterwards. [ 16 ] SMH has been widely used in determining the change of mineralization in enamel carious lesions as the SMH values vary in line with the remaining calcium contents. [ 17 18 ] In fact, there were many factors that could affect the interpretation of SMH values such as sample preparation, indenter position, and the selective area.…”

Comparative evaluation of the remineralizing potential of commercially available agents on artificially demineralized human enamel: An In vitro study

“…This is in accordance with the previous studies done by Vahid Golpayegani et al .,[ 29 ] Karlinsey et al .,[ 37 ] Swarup and Rao,[ 32 ] and Kiranmayi et al . [ 9 ] for determining the RML potential of the agents that were used in the study either individually or in comparison with other agents.…”

“…Till date, the researches in the literature support that fluoride treatment remains the best remineralizing method for early enamel caries. [ 6 7 8 9 ] However, it is difficult for fluoride to result in oriented and ordered mineral crystals on the surface of enamel under physiological conditions due to the lack of ability to guide the formation of mineral crystals. The ordered orientation is essential for the mechanical properties of enamel.…”