PurposeThis paper aims to determine the level of awareness and implementation of family‐responsible parameters: policies, enablers, practices, and culture, in Spanish and Latin‐American companies, and how they impact work‐life balance.Design/methodology/approachThe study uses data from different national IESE's Family‐Responsible Employer Index surveys in Spain (1,000 companies) and five Latin‐American countries (1,155 companies), Brazil, Chile, Colombia, El Salvador and Peru, done between 2006 and 2008. This is a structured questionnaire that assesses the stage of development the organization is in regarding four main family‐responsible parameters: policies, enablers, practices, and culture.FindingsLatin‐American countries get a slightly higher number of companies that are fully supportive of work‐family balance environment than Spain, but with lesser formal policies implemented and a stronger presence of enablers and practices. Policies are important but might not be as effective if not accompanied by the example of managers and staff as well as by a deep understanding of the cultural value placed by them on work, family and personal life.Research limitations/implicationsThe survey‐based data used limits insight into causal relationships. Qualitative and longitudinal studies are needed in order to clarify motives for individual and organizational decisions regarding work‐life initiatives. Data collected are from one source only: employer's management. Multi‐source studies must follow and include the public sector.Originality/valueThis is the first comparison between Spanish companies and companies from five Latin‐American countries regarding work‐family policies, enablers, practices and culture with such an ample number of companies. Findings will aid HRD practitioners in developing work‐family initiatives and help researchers to address new questions in cross‐cultural comparisons.