Arterial aneurysms in patients infected with human immunodeficiency virus: A distinct clinicopathology entity?

Nair, R.; Abdool-Carrim, A.T.O.; Chetty, Runjan; Robbs, J V

doi:10.1016/s0741-5214(99)70304-6

Cited by 77 publications

(78 citation statements)

References 13 publications

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“…5 HIV-associated aneurysms are a distinct clinical entity, generally occurring in younger patients who frequently lack common risk factors for aneurysmal disease. 6 They also tend to be saccular, multiple, are most commonly in the carotid and superficial femoral arteries, and affect the aorta much less frequently than atherosclerotic aneurysms.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous regression of an abdominal aortic aneurysm in an immunocompromised patient

et al. 2010

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Spontaneous aneurysmal regression is a rare event, having been observed only in association with arteritides or immunosuppression following solid-organ transplantation. In particular, the spontaneous regression of an aortic aneurysm, to our knowledge, has never been documented. We report a case of a 46-year-old, HIV-positive, African-American man who developed an asymptomatic juxtarenal abdominal aortic aneurysm, which significantly regressed over a 6-month period in the absence of arteritides or systemic immunosuppressive therapy. This case describes the spontaneous regression of an inflammatory AAA in an HIV-positive patient. Further studies will be required to determine if this was an isolated occurrence or if it occurs with any frequency in specific patient populations.

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Section: Discussionmentioning

confidence: 99%

Spontaneous regression of an abdominal aortic aneurysm in an immunocompromised patient

et al. 2010

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“…There may be another mechanism, in which previous infections of ulcerated atherosclerotic plaque are amplified and destroy the arterial wall, resulting in aneurysms 7 . Nair et al 8 , however, found that culture was positive in only two cases of a series of ten patients with HIV and arterial aneurysms.…”

Section: Discussionmentioning

confidence: 96%

Pseudoaneurismas em associacao com infeccao pelo virus da imunodeficiencia humana: relato de dois casos

et al. 2013

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The authors describe the cases of two patients with pseudoaneurysms, discuss the difficulty in establishing diagnosis and treatment due to human immunodeficiency virus infection, and demonstrate the similarity with atherosclerotic saccular aneurysm of the abdominal aorta.Keywords: HIV; pseudoaneurysm; saccular aneurysm. ResumoOs autores descrevem os casos de dois pacientes que apresentaram pseudoaneurismas e ressaltam a dificuldade diagnóstica e terapêutica por apresentar associação com a infecção pelo vírus da imunodeficiência humana, e também demonstram a semelhança com aneurisma sacular aterosclerótico da aorta abdominal.Palavras-chave: HIV; pseudoaneurisma; aneurisma sacular. As the patient was obese, had previous abdominal surgery and her anatomy was favorable, the plan was to use an endovascular approach to place an aortic endoprosthesis for aneurysm repair.Right femoral dissection and left femoral puncture were used to place a 25 mm × 16 mm × 100 mm Powerlink R endoprosthesis (Endologix, Irvine, CA) using a 9F introducer sheath, and the aneurysm was immediately repaired. Post-operative progression was good, and the patient was discharged on the second day after operation. Ten days after the operation, she presented with left lower back pain, diarrheic stools, vomiting and paresthesia of left lower extremity. Physical examination detected femoral and distal pulses and no sign of hyperemia in the surgical wound; laboratory tests were normal. Two days after hospitalization, her general state deteriorated and she had abdominal and lower extremity pain. Physical examination found that the lower extremities were cold, and no pulses should be detected. Ultrasound scanning confirmed the clinical hypothesis of endoprosthesis occlusion. She underwent an urgent surgery for an axillobifemoral bypass and placement of an 8-mm Dacron prosthesis, and revascularization of the lower extremities was successful. After operation in the ICU, she was administered broad spectrum antibiotics (vancomycin 1 g, 12h/12h and meropenem 1 g, 8h/8h), but had refractory septic shock and died. Case 2A previously healthy 47-year-old male smoking patient was transferred from another hospital ward with a history of daily low fever for 20 days. Nine

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“…(52) Nair et al (53,54) (1997, 2000) encountered these entities locally: they felt that the histological similarities in the 2 conditions would have "a common pathogenetic event". In the absence of micro-organisms and atherosclerosis, it was suggested that the virus might directly involve the vessel.…”

Section: Vascularmentioning

confidence: 99%

Human Immunodeficiency Virus disease and cardiac surgery – where are we?

Blyth¹

2017

SAHJ

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operatively and 3 died of sepsis after completion of appropriate antibiotic therapy. Three with pre-operative control of AIE left VALVE SURGERYThe landmark paper by Frater and colleagues (2) in 1989 showed that human immuno-defi ciency virus (HIV+) patients could be taken through surgery successfully. Striking features were: all but 1 of the 10 patients having 11 valve replacements, for infective endocarditis (IE) were intravenous drug addicts (IVDA), and, further, despite conventional medical therapy, 7 of these still had active infective endocarditis (AIE) at surgery (Table 1)

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Arterial aneurysms in patients infected with human immunodeficiency virus: A distinct clinicopathology entity?

Cited by 77 publications

References 13 publications

Spontaneous regression of an abdominal aortic aneurysm in an immunocompromised patient

Spontaneous regression of an abdominal aortic aneurysm in an immunocompromised patient

Pseudoaneurismas em associacao com infeccao pelo virus da imunodeficiencia humana: relato de dois casos

Human Immunodeficiency Virus disease and cardiac surgery – where are we?

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