Arthroscopic evaluation of the synovial membrane and its relationship with histological changes and biomarkers in equine joint disease

Agreste, Fernanda Rodrigues; Moreira, Jaqueline Costa Castilho; Fülber, Joice; Bogossian, Paulo Moreira; Chaible, Lucas Martins; Silva, Luís Cláudio Lopes Correia da; Michelacci, Yára M.; Baccarin, Raquel Yvonne Arantes

doi:10.1016/j.rvsc.2021.09.003

Cited by 2 publications

(1 citation statement)

References 37 publications

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“…Arthroscopy allows direct visualization and subjective evaluation of synovial structures. In osteoarthritic joints, the assessment of synovial membrane shape during surgical arthroscopy showed a high correlation with their histological aspects, allowing it to be a good indicator of the ongoing inflammatory process ( Agreste et al, 2021 ). Further information, such as surface integrity, thickness and stiffness of articular cartilage, and integrity of ligaments, can also be assessed ( McIlwraith et al, 2014 ).…”

Section: Diagnosis Of Osteoarthritis In Horsesmentioning

confidence: 99%

Osteoarthritis: a common disease that should be avoided in the athletic horse’s life

et al. 2022

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Section: Diagnosis Of Osteoarthritis In Horsesmentioning

confidence: 99%

Osteoarthritis: a common disease that should be avoided in the athletic horse’s life

et al. 2022

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Administration of sodium hyaluronate to adult horses prior to and immediately after exercise does not alter the range of motion in either the tarsus or metacarpophalangeal joints

Riley,

Chance,

Barshick

et al. 2024

Translational Animal Science

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Hyaluronic acid (HA), a glycosaminoglycan found in joint synovial fluid, is administered to horses as an anti-inflammatory with lubrication properties. This experiment examined the effects of HA administered before and shortly after an exercise test on metacarpophylangeal (MCP; fetlock) and tibiotarsal (hock) joint range of motion (ROM). Horses were injected intravenously (IV) with placebo (4 mL, saline) or HA (4 mL, 40 mg) 24 h before performing a standardized exercise test (SET) on a high-speed treadmill and again at 6-h post-SET. Passive fetlock flexion was measured at 4 and 24 h post-SET. Hock flexion and extension was measured at 24 h post-SET by videography and kinematic evaluation at the trot. Parameters of the SET were sufficient to cause peak lactate values of 6.6 ± 0.15 mM and maximum heart rate of 203.6 ± 4.8 bpm. A minor gain (P = 0.08) in fetlock flexion prior to SET was observed in HA horses that was not retained at either 4 or 24 h post-SET. Hock flexion in both limbs was greater (P < 0.05) at 24 h post-SET, independent of treatment. Horses receiving HA exhibited reduced (P = 0.04) right hock extension. No differences in either right or left hock ROM were observed between control and HA treated horses. From these results, it is concluded that IV HA injections surrounding an exercise stressor offer no substantive gains in either fetlock or hock ROM.

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Arthroscopic evaluation of the synovial membrane and its relationship with histological changes and biomarkers in equine joint disease

Cited by 2 publications

References 37 publications

Osteoarthritis: a common disease that should be avoided in the athletic horse’s life

Osteoarthritis: a common disease that should be avoided in the athletic horse’s life

Administration of sodium hyaluronate to adult horses prior to and immediately after exercise does not alter the range of motion in either the tarsus or metacarpophalangeal joints

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