AS-183 Percutaneous Coronary Intervention (PCI) of Chronic Total Occlusion (CTO) Lesion : Our Experience, In-hospital and 90-days Outcome

Talukder, Shahabuddin; Isla, Ahm Waliul; Munwar, Shams; Reza, Aqm; Ahmed, Tamzeed; Bhuiyan, A.H.; Masud, Rowsan; Siddique, Atique Bin; Shohel, Shaifur Rahman; Ghani, Mohammed; Alam, M.S.; Miah, A.

doi:10.1016/j.amjcard.2012.01.214

Cited by 1 publication

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“…Medication alone for CTO treatment does reduce the clinical symptom, but it has little effect on the long-term heart function and the improvement of the patients’ survival rate. Percutaneous coronary intervention (PCI) is a therapeutic procedure not only used to recanalize vessels with total occlusion [ 4 ], but also widely used in other aspects such as increase blood flow reperfusion, improve myocardial contractile and pump function [ 5 ], inhibit left ventricular remodeling and decrease adverse cardiac events [ 6 ]. However, PCI is considered not suitable for CTO lesions because of the lack in strong backup support by the guiding catheters or the difficulty in taking the contralateral coronary angiograms [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

RETRACTED ARTICLE: Meta-analysis of the effect of percutaneous coronary intervention on chronic total coronary occlusions

Yang

Tang

et al. 2014

J Cardiothorac Surg

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Background and purposeCoronary chronic total occlusion (CTO) is the last stage of coronary artery atherosclerosis. Percutaneous coronary intervention (PCI) is a therapeutic procedure used to recanalize vessels with total occlusion. However, successful recanalization of CTO is still not optimal, and the key influence factors are still uncertainty. Therefore, a scientific evaluation on the effective of PCI for CTO treatment is necessary.MethodsRelevant studies of PCI treatment for CTO were examined. Data were extracted and assessed by two independent clinical experts. Embase, PubMed and Medline et al. were used as database. The main research key words include “CTO”, “PCI”, “Stent”, “Reopen”, “long-term”, “follow-up” and “outcome”. Quality assessment was carried out according to the Cochrane Handbook. The selected data were pooled and analyzed using fixed-effect model and random-effect model. Heterogeneity was assessed using the I2 test, Q test, L’abbe and Galbraith. Comprehensive Meta -Analysis 2.0 and Metanalysis 1.0 were used for statistics analysis in this research.ResultsA total of 16 articles involving 6695 cases in successful CTO recanalization (CTO success group) and 2370 cases in failed CTO recanalization(CTO failure group) were included in this research. Low CTO success was associated with elder age, previous coronary artery bypass graft surgery (CABG) history, multi-vessel diseases and right coronary artery disease lesion. Six follow-up variables including major adverse cardiac events (MACE), recurrent myocardial infarction (MI), all-cause death, incidence of angina, subsequent CABG and cumulative survival rate were found significantly reduced associated with CTO success.ConclusionsClinical baseline characteristics such as age, previous CABG history and lesion baseline characteristics such as lesion length, multi-vessel diseases might be important factors influencing the successful rate of CTO recanalization. Compared to CTO failure patients, all six follow-up variables showed advantage for CTO success patients.

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