2014
DOI: 10.2478/bvip-2014-0016
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Assessment of CD11b and CD11/18 integrin expression on leukocytes of dogs with atopic dermatitis

Abstract: Cytometric analysis was performed in order to detect the expression of surface molecules CD11b and CD11/18 on lymphocytes, granulocytes, and monocytes of peripheral blood of dogs with atopic dermatitis (AD) complicated by purulent dermatitis. The percentage of peripheral blood lymphocytes with CD11b and CD11/18 was found to be significantly higher (P < 0.05) in dogs with AD than in healthy dogs. The percentage of granulocytes expressing CD11b molecule was significantly lower in dogs with complicated AD compare… Show more

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Cited by 2 publications
(1 citation statement)
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“…One of them is CD11b integrin, an α chain of the leukocyte β2-integrin, Mac-1, which mediates binding and extravasation of leukocytes. In dogs, most of the leukocytes express surface CD11b integrins [ 16 ]. In addition, CD11b is a marker that is present on myeloid derived suppressor cells (MDSC) and tumor associated macrophages [ 17 , 18 ].…”
Section: Introductionmentioning
confidence: 99%
“…One of them is CD11b integrin, an α chain of the leukocyte β2-integrin, Mac-1, which mediates binding and extravasation of leukocytes. In dogs, most of the leukocytes express surface CD11b integrins [ 16 ]. In addition, CD11b is a marker that is present on myeloid derived suppressor cells (MDSC) and tumor associated macrophages [ 17 , 18 ].…”
Section: Introductionmentioning
confidence: 99%