Assessment of prevalence and risk factors of helicobacter pylori infection in an oilfield Community in Hebei, China

Abstract

BackgroundOnly a paucity of large-scale perspective and cross-sectional studies on H. pylori infection in China have been published. The purpose of this study was to investigate the prevalence and risk factors for H. pylori infection among residents of Jidong community located in Hebei Province of China.MethodsA perspective, cross-sectional study was conducted in Jidong community. Questionnaires and 13C-urea breath test were performed, and 10-ml blood samples were obtained for laboratory tests.ResultsFour thousand seven hundred ninety-six subjects were enrolled in this study, and 2506 (52.25%) were H. pylori positive. There was no difference in prevalence between both sexes (P = 0.5974). Age (P = 0.004) and education level (P = 0.0128) were significantly associated with H. pylori infection, and there were statistical trends in the prevalence across five age subgroups (χ2 test for trend = 23.5; P < 0.001) and education levels (χ2 test for trend = 19.50; P < 0.001). H. pylori infection was also associated with marital status (P = 0.0243), source of drinking water (P = 0.0433), frequency of eating raw garlic (P = 0.0310), alcohol drinking (P = 0.0207), knowledge about H. pylori transmission route (P = 0.0125) and related diseases (P = 0.0257). Age, alcohol drinking and knowledge about transmission route were found to be independent predictors of H. pylori infection.ConclusionsMore than half of the population was infected with H. pylori in Jidong community. The socio-demographic profiles, socio-economic factors and lifestyle are worthy taking into consideration to prevent diseases associated with H. pylori infection. Understanding the prevalence and risk patterns for H. pylori infection in China will help in prioritizing public health efforts to better manage the H. pylori infection.

Sex differences in the relationship among alcohol, smoking, and Helicobacter pylori infection in asymptomatic individuals

“…These findings support the hypothesis that moderate alcohol consumption may facilitate spontaneous elimination of H. pylori infection in adults. 18 On the contrary, Wang et al 19 suggested that patients who consumed alcohol had a higher prevalence of active H. pylori infection than non-drinkers (OR: 1.139; 95% CI: 1.025-1.290; P ¼ 0.0407). Zhang et al 20 reported that in patients with functional dyspepsia, there is no significant association between active H. pylori infection and smoking.…”

Epidemiological Profile of Helicobacter pylori Infection in Patients with Digestive Symptoms in Algeria

“…Our results are similar to those in European countries, which are around 60 years old [ 25 ]. It has been reported that the prevalence of H. pylori infection increased by age manner [ 35 ].…”

Review: Epidemiology of Helicobacter pylori

“…The infection was found more frequently in married subjects than singles ( P = .02), those with a lower education level ( P = .01), using barreled vs. piped water ( P = .04), and more frequently consuming garlic ( P = .03) as well as in alcohol consumers when compared to non‐drinkers ( P = .02). Furthermore, responders that were familiar with the route of H pylori transmission and related diseases had a lower prevalence of the infection than those who were not aware ( P = .01, P = .03, respectively) 7 …”

“…A prospective, cross‐sectional study HIOC ( Helicobacter pylori Infection in Oilfield Community) involving employees and their family members was conducted in the Jidong community of Hebei province, China 7 . Among the 4796 consecutive study subjects tested by UBT, H pylori infection was present in 52.3%.…”