Assessment of reperfusion therapy on regional and global left ventricular function in patients with chronic total coronary artery occlusions

Ermis, Cengiz; Boz, Adil; Tholakanahalli, Venkat; Yalçinkaya, Selim; Semiz, Ender; Sancaktar, Oktay; Miller, Leslie W.; Değer, Necmi; Benditt, David G.

doi:10.1016/s0735-1097(02)81308-0

Cited by 8 publications

(12 citation statements)

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“…However, in multivariable analysis, angina class had no significant association with long-term survival. This differs from prior reports, in which increased mortality correlated with severity of angina in stable outpatients (17), and improvements in left ventricular function following CTO PCI correlated with angina severity (18).…”

Section: Discussioncontrasting

confidence: 99%

“…There are also improvements in clinical outcomes such as reduced incidence of MI, reduced need for CABG, and significant reductions in angina burden after CTO PCI (7,23). Improvements in regional and global wall motion are evident on myocardial perfusion scintigraphy, echocardiography, and left ventriculography following PCI of CTO (18,24,25). Positive effects on left ventricular remodeling have been reported in patients undergoing cardiac magnetic resonance imaging up to 3 years after CTO PCI (26).…”

Section: Discussionmentioning

confidence: 97%

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Improvement in Survival Following Successful Percutaneous Coronary Intervention of Coronary Chronic Total Occlusions: Variability by Target Vessel

Safley

House

Marso

et al. 2008

JACC: Cardiovascular Interventions

140

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 97%

Improvement in Survival Following Successful Percutaneous Coronary Intervention of Coronary Chronic Total Occlusions: Variability by Target Vessel

Safley

House

Marso

et al. 2008

JACC: Cardiovascular Interventions

140

View full text Add to dashboard Cite

show abstract

“…Previous study reveals that PCI significantly improved both the local and global function of the left ventricle in CTO patients [34]. Such procedure is beneficial for the symptom in selected patients [35].…”

Section: Discussionmentioning

confidence: 99%

RETRACTED ARTICLE: Meta-analysis of the effect of percutaneous coronary intervention on chronic total coronary occlusions

Yang

Tang

et al. 2014

J Cardiothorac Surg

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Background and purposeCoronary chronic total occlusion (CTO) is the last stage of coronary artery atherosclerosis. Percutaneous coronary intervention (PCI) is a therapeutic procedure used to recanalize vessels with total occlusion. However, successful recanalization of CTO is still not optimal, and the key influence factors are still uncertainty. Therefore, a scientific evaluation on the effective of PCI for CTO treatment is necessary.MethodsRelevant studies of PCI treatment for CTO were examined. Data were extracted and assessed by two independent clinical experts. Embase, PubMed and Medline et al. were used as database. The main research key words include “CTO”, “PCI”, “Stent”, “Reopen”, “long-term”, “follow-up” and “outcome”. Quality assessment was carried out according to the Cochrane Handbook. The selected data were pooled and analyzed using fixed-effect model and random-effect model. Heterogeneity was assessed using the I2 test, Q test, L’abbe and Galbraith. Comprehensive Meta -Analysis 2.0 and Metanalysis 1.0 were used for statistics analysis in this research.ResultsA total of 16 articles involving 6695 cases in successful CTO recanalization (CTO success group) and 2370 cases in failed CTO recanalization(CTO failure group) were included in this research. Low CTO success was associated with elder age, previous coronary artery bypass graft surgery (CABG) history, multi-vessel diseases and right coronary artery disease lesion. Six follow-up variables including major adverse cardiac events (MACE), recurrent myocardial infarction (MI), all-cause death, incidence of angina, subsequent CABG and cumulative survival rate were found significantly reduced associated with CTO success.ConclusionsClinical baseline characteristics such as age, previous CABG history and lesion baseline characteristics such as lesion length, multi-vessel diseases might be important factors influencing the successful rate of CTO recanalization. Compared to CTO failure patients, all six follow-up variables showed advantage for CTO success patients.

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“…Only one randomized‐controlled trial (RCT) was identified . Thirty‐four observational studies [including two abstracts ] with a total of 2804 patients met our inclusion criteria . Cardiac magnetic resonance imaging (CMR) was used to assess LVEF in nine studies while echocardiography was used in 10 studies .…”

Section: Resultsmentioning

confidence: 99%

Meta‐analysis of the impact of successful chronic total occlusion percutaneous coronary intervention on left ventricular systolic function and reverse remodeling

Megaly

Saad

Tajti

et al. 2018

J Interven Cardiology

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Assessment of reperfusion therapy on regional and global left ventricular function in patients with chronic total coronary artery occlusions

Cited by 8 publications

References 0 publications

Improvement in Survival Following Successful Percutaneous Coronary Intervention of Coronary Chronic Total Occlusions: Variability by Target Vessel

Improvement in Survival Following Successful Percutaneous Coronary Intervention of Coronary Chronic Total Occlusions: Variability by Target Vessel

RETRACTED ARTICLE: Meta-analysis of the effect of percutaneous coronary intervention on chronic total coronary occlusions

Meta‐analysis of the impact of successful chronic total occlusion percutaneous coronary intervention on left ventricular systolic function and reverse remodeling

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