Assisted reproduction techniques in Latin America: the Latin American Registry, 2014

Zegers‐Hochschild, Fernando; Schwarze, Juan Enrique; Crosby, Javier; Musri, Carolina; Urbina, María Teresa

doi:10.1016/j.rbmo.2017.05.021

Cited by 13 publications

(9 citation statements)

References 7 publications

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“…In spite of advanced progress in assisted reproduction technology (ART) over the past 20 years, the effectiveness of embryo transfer (ET) per cycle is still relatively low. In 2015, the delivery rate (DR) per ET in Latin America reached 25.6% in fresh autologous ET, and 36.8% when using donated eggs ( Zegers-Hochschild et al ., 2017a ; b ).…”

Section: Introductionmentioning

confidence: 99%

Atosiban improves the outcome of embryo transfer. A systematic review and meta-analysis of randomized and non-randomized trials

Schwarze¹,

Crosby²,

Mackenna³

2020

JBRA Assisted Reproduction

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Objective: To estimate the effectiveness of Atosiban in improving the outcome after embryo transfer. The effectiveness of embryo transfer per cycle is still relatively low. One possible explanation might be uterine contractility that expels the transferred embryos. Atosiban improved the outcome of embryo transfer by reducing uterine contractility. Methods: Data sources: A systematic review of papers in English using MEDLINE and EMBASE (1990-2019). Search terms included Atosiban, embryo transfer. Study selection: We included studies that compared the outcomes of embryo transfer with Atosiban and a control group. Data Extracting: Independent extraction of papers by two authors, using predefined data fields, including study quality indicators. Results: All pooled analyses were based on a fixed-effect model. Four randomised controlled trials, including 1,025 women, and two non-randomised trials, including 686 patients, met our inclusion criteria. In both studies, the heterogeneity was moderate. Atosiban increased clinical pregnancy rates regardless of the indication for ART or type of embryo transferred. Pooled OR in randomized controlled trials reached 1.47 (1.18-1.82), and in non-randomised controlled trials it reached 1.50 (95% CI 1.10-2.05) Conclusion: Atosiban appears to increase the clinical pregnancy rates in women undergoing embryo transfer.

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Section: Introductionmentioning

confidence: 99%

Atosiban improves the outcome of embryo transfer. A systematic review and meta-analysis of randomized and non-randomized trials

Schwarze¹,

Crosby²,

Mackenna³

2020

JBRA Assisted Reproduction

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“…Overall, the number of reported initiated cycles increased by 15% (Zegers-Hochschild et al ., 2017a;b) with respect to the previous year. However, access to ART in Latin America (133 initiated cycles/million population) remains very much under the threshold of 1500 cycles per annum per million inhabitants proposed by the ESHRE Capri Group, in order to fulfil the ART needs of a population (The ESHRE Capri Workshop Group, 2001).…”

Section: Discussionmentioning

confidence: 99%

“…Definitions used refer to the glossary developed by the International Committee for Monitoring Assisted Reproductive Technologies (ICMART) and the World Health Organization (WHO) (Zegers-Hochschild et al., 2009). Preimplantation genetic diagnosis and screening are registered together as preimplantation genetic testing (PGT) (Zegers-Hochschild et al, 2017a;b).…”

Section: Methodsmentioning

confidence: 99%

Assisted Reproductive Techniques in Latin America: The Latin American Registry, 2015

Zegers‐Hochschild

Schwarze

Crosby

et al. 2019

JBRA Assisted Reproduction

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Research question: What was the utilization, effectiveness and safety of assisted reproductive technologies (ART) performed in Latin American countries during 2015, and what were the regional trends? Design: Retrospective collection of multinational data on assisted reproduction techniques (IVF and intracytoplasmic sperm injection [ICSI], frozen embryo transfer, oocyte donation, preimplantation genetic testing and fertility preservation), from 175 institutions in 15 Latin American countries. Results: In total, 41.25% of IVF/ICSI cycles were performed in women aged 35-39 years, and 28.35% in women aged ≥40 years. After removing freeze-all cycles, delivery rate per oocyte retrieval was 21.39% for ICSI and 24.29% for IVF. Multiple births included 19.58% twins and 0.95% triplets and higher. In oocyte donation, delivery rate per transfer was 36.77%, with a twin and triplet rate of 27.65% and 1.06%, respectively. Overall, preterm deliveries reached 17.38% in singletons, 64.94% in twins and 98.41% in triplets. Perinatal mortality in 14,936 births and 18,391 babies born was 10.5 per 1000 in singletons, 17.9 per 1000 in twins, and 57.1 per 1000 in high-order multiples. Elective single embryo transfer represented 3.11% of fresh transfers, with a 31.78% delivery rate per transfer. Elective double embryo transfer represented 23.3% of transfers, with a 37.79% delivery rate per transfer. Out of 18,391 babies born, 63.22% were singletons, 34.4% twins, and 2.38% triplets and higher. Conclusions: Given the effect of multiple births on prematurity, morbidity and perinatal mortality, reinforcing the existing trend of reducing the number of embryos transferred remains mandatory.

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“…• O índice de gravidez positiva em grandes laboratórios e clinicas de RA é em média de 50%, porém considerando a idade materna essa porcentagem cai drasticamente de acordo com dados publicados pela Rede Latino-americana 8 de Reprodução Assistida, de 2014.…”

Section: Reprodução Assistidaunclassified

Biodireito e legislação na reprodução assistida

Araujo¹,

Araujo

2018

Medicina (Ribeirao Preto. Online)

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O biodireito é um ramo da ciência jurídica, e por essa lente podemos analisar os princípios e normas que influenciam e modificam as relações com o Estado e entre os próprios indivíduos, quando tratarem sobre a vida e dos direitos fundamentais dos indivíduos envolvidos. Os principais princípios analisados da bioética são: beneficência, autonomia, justiça, respeito pela pessoa e do consentimento informado. As pesquisas buscam trazer foco na legislação brasileira a respeito do assunto, a fim de propor uma maior abordagem para facilitar a compreensão das pessoas envolvidas no processo de Reprodução Assistida, tanto pacientes como profissionais. As normas analisadas foram a Constituição Federal, o Código Civil Brasileiro e as Resoluções do Conselho Federal de Medicina (CFM). O texto trata de assuntos polêmicos que envolvem pacientes, equipe multiprofissional e sociedade, pois ao analisar as técnicas de Reprodução Assistida há inúmeras indagações como por exemplo quais os direitos e deveres envolvidos, qual o limite do uso dessas técnicas para ter como resultado a gravidez e quais os direitos fundamentais que estão sendo preservados. Alguns pontos discutidos no trabalho são da cessão temporária do útero, doação de material genético, criopreservação e Reprodução Assistida post-mortem, entre outros. Assim, o desenvolvimento do tema exposto se dá em três momentos, sendo o primeiro o biodireito e os direitos humanos do ponto de vista da Reprodução Assistida, bem como as técnicas utilizadas, em seguida o estudo da legislação brasileira e por fim os aspectos polêmicos e discussões a respeito do tema.

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Assisted reproduction techniques in Latin America: the Latin American Registry, 2014

Cited by 13 publications

References 7 publications

Atosiban improves the outcome of embryo transfer. A systematic review and meta-analysis of randomized and non-randomized trials

Atosiban improves the outcome of embryo transfer. A systematic review and meta-analysis of randomized and non-randomized trials

Assisted Reproductive Techniques in Latin America: The Latin American Registry, 2015

Biodireito e legislação na reprodução assistida

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