Association Between Alcohol Intake and Development of Hypertension in Japanese Normotensive Men: 12-Year Follow-Up Study

Tsuruta, Makoto; Adachi, Hisashi; Hirai, Yuji; Fujiura, Yoshihisa; Imaizumi, Tsutomu

doi:10.1016/s0895-7061(99)00238-1

Cited by 64 publications

(51 citation statements)

References 23 publications

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“…Como cabía esperar, los resultados concuerdan con la hipótesis que establece que un consumo excesivo de alcohol incrementa el riesgo de hipertensión arterial [22][23][24] y respalda las recomendaciones generales sobre la reducción del consumo de alcohol como medida para prevenir la hipertensión arterial 25 .…”

Section: Discussionunclassified

Alcohol Consumption and the Incidence of Hypertension in a Mediterranean Cohort: The SUN Study

Núñez‐Córdoba

Martínez‐González

Bes–Rastrollo

et al. 2009

Revista Española de Cardiología (English Edition)

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Section: Discussionunclassified

Alcohol Consumption and the Incidence of Hypertension in a Mediterranean Cohort: The SUN Study

Núñez‐Córdoba

Martínez‐González

Bes–Rastrollo

et al. 2009

Revista Española de Cardiología (English Edition)

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“…[62][63][64] Tsuruta et al 62 reported that the probability of the development of hypertension in heavy drinkers (alcohol consumption^46 g per day) was about twice that of the rest of the population after a 12-year follow-up among normotensive men. Fuchs et al 63 showed that the consumption of alcohol at^30 g per day was an independent risk factor among participants in the Atherosclerosis Risk in Communities (ARIC) study.…”

Section: Actions Of Alcohol On Water and Electrolyte Metabolismmentioning

confidence: 99%

Physio-pathological effects of alcohol on the cardiovascular system: its role in hypertension and cardiovascular disease

Kawano

2010

Hypertens Res

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Alcohol has complex effects on the cardiovascular system. The purpose of this article is to review physio-pathological effects of alcohol on cardiovascular and related systems and to describe its role in hypertension and cardiovascular disease. The relationship between alcohol and hypertension is well known, and a reduction in the alcohol intake is widely recommended in the management of hypertension. Moreover, alcohol has both pressor and depressor actions. The latter actions are clear in Oriental subjects, especially in those who show alcohol flush because of the genetic variation in aldehyde dehydrogenase activity. Repeated alcohol intake in the evening causes an elevation in daytime and a reduction in nighttime blood pressure (BP), with little change in the average 24-h BP in Japanese men. Thus, the hypertensive effect of alcohol seems to be overestimated by the measurement of casual BP during the day. Heavy alcohol intake seems to increase the risk of several cardiovascular diseases, such as hemorrhagic stroke, arrhythmia and heart failure. On the other hand, alcohol may act to prevent atherosclerosis and to decrease the risk of ischemic heart disease, mainly by increasing HDL cholesterol and inhibiting thrombus formation. A J-or U-shaped relationship has been observed between the level of alcohol intake and risk of cardiovascular mortality and total mortality. It is reasonable to reduce the alcohol intake to less than 30 ml per day for men and 15 ml per day for women in the management of hypertension. As a small amount of alcohol seems to be beneficial, abstinence from alcohol is not recommended to prevent cardiovascular disease. INTRODUCTIONAlcohol has complex effects on the cardiovascular system. The relationship between alcohol and hypertension is well known, and a restriction of alcohol intake is widely recommended as a part of lifestyle modifications in the management of hypertension. 1-6 Alcohol has both pressor and depressor actions, however, and the genetic susceptibility regarding alcohol metabolism influences the cardiovascular effect of alcohol. 3,7 The effect of alcohol on blood pressure (BP) is also modified by several factors, such as the level of consumption, time period after the last drink and overall drinking behavior.Alcohol consumption is associated with several cardiovascular diseases, such as brain hemorrhage, heart failure and arrhythmia, as well as with other disorders. 3,[8][9][10][11] Heavy drinking and alcoholism not only lead to medical problems but are also serious social concerns. However, alcohol also seems to have beneficial effects, including the prevention of ischemic heart disease. It has been shown that cardiovascular and all-cause mortality is lower in light drinkers compared with nondrinkers. 3,[8][9][10][11][12] The purpose of this article is to review physio-pathological effects of alcohol on cardiovascular and related systems and to describe its role

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“…Alcohol consumption has been associated with the development of hypertension (1)(2)(3)(4)(5)(6)(7)(8)(9)(10), and Japanese men consume more alcoholic beverages than men in many other developed countries, including the United States and the United Kingdom (11)(12)(13)(14)(15). These facts suggest that the high consumption of alcoholic beverages among Japanese men may contribute to the high prevalence of hypertension in Japan (12,16).…”

Section: Introductionmentioning

confidence: 99%

The Proportion of Individuals with Alcohol-Induced Hypertension among Total Hypertensives in a General Japanese Population: NIPPON DATA90

et al. 2007

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, for the NIPPON DATA90 Research Group* Japanese men consume more alcoholic beverages than men in many other developed countries. The high consumption rate of alcoholic beverages among Japanese men may contribute to the high prevalence of hypertension in Japan. In the present study, we calculated the odds ratio for hypertension in alcohol drinkers based on recent criteria using data from a nationwide survey conducted in Japan in 1990, and estimated, among total hypertensives in a general Japanese population, the percentage of hypertensives whose condition was due to alcohol consumption. Of 3,454 male participants, 64.8% were drinkers (1 gou/day, 28.9%; 2 gou/day, 20.1%; 3 gou/day or more, 8.7%; ex-drinkers, 7.0%) and 49.8% were hypertensive, whereas 7.6% of 4,808 female participants were drinkers (1 gou/day, 5.2%; 2 gou/day or more, 1.3%; ex-drinkers, 1.1%) and 43.1% were hypertensive (1 gou =23.0 g of alcohol). In both sexes, drinkers had a higher odds ratio for hypertension than never drinkers, and there was a significant dose-response relationship between the amount of alcohol consumed and the odds ratio for hypertension. Among all hypertensives, the percentage whose hypertension was due to alcohol consumption was 34.5% (95% confidence interval, 10.9%-51.9%) for men and 2.6% (0.8%-5.8%) for women. The corresponding proportion based on daily alcohol intake was 12.7% for 1 gou/day, 11.1% for 2 gou/day, 5.8% for 3 gou/day or more, and 4.8% for ex-drinkers in men, and 1.8% for 1 gou/day, 0.7% for 2 gou/day or more, and -0.1% for ex-drinkers in women. In conclusion, we found that a large percentage of the hypertensives in a general Japanese male population had alcohol-

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Association Between Alcohol Intake and Development of Hypertension in Japanese Normotensive Men: 12-Year Follow-Up Study

Cited by 64 publications

References 23 publications

Alcohol Consumption and the Incidence of Hypertension in a Mediterranean Cohort: The SUN Study

Alcohol Consumption and the Incidence of Hypertension in a Mediterranean Cohort: The SUN Study

Physio-pathological effects of alcohol on the cardiovascular system: its role in hypertension and cardiovascular disease

The Proportion of Individuals with Alcohol-Induced Hypertension among Total Hypertensives in a General Japanese Population: NIPPON DATA90

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