Association Between New Platelet Indices And Calcific Aortic Stenosis:  Plateletcrit And Platelet to Lymphocyte Ratio

Çakmak, Hüseyin Altuğ; Enhoş, Asım; Ertürk, Mehmet; Kalkan, Ali Kemal; Satılmışoğlu, Muhammet Hulusi; Gül, Mehmet

doi:10.5505/vtd.2016.47955

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…Increased plateletcrit and PLR have been shown to affect the prothrombotic and proinflammatory processes [27]. Plateletcrit and PLR, therefore, have been studied in many obstetric complications.…”

Section: Discussionmentioning

confidence: 99%

Can hematologic inflammation markers be the indicator of early pregnancy loss?

Onat¹,

Kırmızı²,

Çaltekin³

et al. 2020

Journal of Surgery and Medicine

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Aim: Pregnancy loss occurs in 50% of human pregnancies and is the most common complication of early pregnancy. The aim of this study is to evaluate the relationship between early pregnancy loss and inflammation with hematological markers. Methods: This case-control study was carried out between January 2016-March 2019 in our clinic to evaluate the cases of early pregnancy loss. The early pregnancy loss group consisted of 94 patients, while the control group consisted of 104 women giving normal birth. Demographic data and complete blood count results of the groups were obtained from the patient files and hospital information management systems. Results: There were no statistically significant differences in terms of age and body mass index between the two groups. Pregnancy losses in the abortion group occurred at an average of 9.03 (3.62) weeks. In the abortus group, platelet count (P=0.003), NLR (P=0.036), PLR (P=0.032) and plateletcrit (P=0.007) were higher, while LMR (P=0.034) was lower, compared to the control group. Conclusions: Hematological inflammation parameters are easy to perform and cost-effective examinations. In our study, the success of these parameters to predict early pregnancy loss was evaluated, and it was found that although there are significant differences in hematological inflammation markers between the groups, the sensitivity and specificity of these markers are low.

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Section: Discussionmentioning

confidence: 99%

Can hematologic inflammation markers be the indicator of early pregnancy loss?

Onat¹,

Kırmızı²,

Çaltekin³

et al. 2020

Journal of Surgery and Medicine

View full text Add to dashboard Cite

show abstract

“…Increased plateletcrit has been associated with poor prognosis in thromboembolic events. [17,18] Possible explanations in the literature include thrombus formation due to exaggerated platelet activity and increased blood viscosity and aggregability resulting in increased plateletcrit. [18] Since PDW is a specific platelet activation marker, it has been reported to increase in thromboembolic events.…”

Section: Discussionmentioning

confidence: 99%

“…[17,18] Possible explanations in the literature include thrombus formation due to exaggerated platelet activity and increased blood viscosity and aggregability resulting in increased plateletcrit. [18] Since PDW is a specific platelet activation marker, it has been reported to increase in thromboembolic events. [19,20] Several other possible mechanisms have been suggested for the increase in PDW in thromboembolic events.…”

Section: Discussionmentioning

confidence: 99%

The Role of Platelet Indices in Predicting Short-Term Mortality in Elderly Patients with Pulmonary Embolism

Özdemir

Algın²

2021

Journal of Contemporary Medicine

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Objective: This study aimed to investigate the role of platelet count, mean platelet volume (MPV), plateletcrit, platelet distribution width (PDW), platelet mass index (PMI), and MPV-to-platelet count ratio (MPR) in predicting short-term mortality in patients aged 65 and over with pulmonary embolism. Methods: This retrospective, observational, cohort study included corrected pulmonary embolism patients. Demographics, clinical characteristics, and platelet indices and the data of all-cause mortality within 30 days after admission were noted. The receiver operating characteristic curve analysis and multivariate analysis was performed to determine the discriminative ability of the scores. Results: A final analysis of 128 patients was performed. The mortality rate was 21.8%. There was no significant relationship in the multivariate analysis between mortality and platelet indices (Mann-Whitney U test). Area under curves of neutrophil-to-lymphocyte ratio, PMI, MPR, plateletcrit, platelet count, and MPV are 0.501, 0.640, 0.626, 0.642, 0.633, and 0.532, respectively. Conclusion As a conclusion based on results of our simple, platelet indices could not predict short-term mortality in elderly patients with pulmonary embolism.

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Comparison of Platelet Mass Index in On-Pump and Off-Pump Coronary Artery Bypass Surgery

Gülbaran

Çiftçi

2020

HSF

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Introduction: Platelet mass index (PMI) is calculated by multiplying platelet count and mean platelet volume (MPV). It demonstrates platelet activation and is thought to be associated with inflammation. Its importance for cardiac surgery has not yet fully been clarified. This study investigates whether there is a difference between PMI levels after on-pump and off-pump coronary artery bypass surgery and the relationship between early postoperative complications and PMI. Method: In our hospital, 138 patients were included in the study retrospectively. The patients were divided into 2 groups: Group 1 (on-pump) with 80 patients (22 females, 58 males, mean age 61.54 ± 8.68) and Group 2 (off-pump) with 58 patients (15 females, 43 males, mean age 61.34 ± 10.04). In biochemical analysis, hemoglobin, platelet, white blood cell, and MPV values of the patients were evaluated in the biochemistry laboratory of our hospital with the blood taken preoperatively from the forearm veins and postoperatively on the first, third, and seventh days and, on average, after the first month. Results: There was a statistically significant difference between postoperative first day thrombocyte (K/µL) (P = .005), postoperative first day PMI (P = .014), postoperative first day leukocyte (K/µL) (P = .001), postoperative first day Hb (g/dL) (P = .001), postoperative third day thrombocyte (K/µL) (P = .003), postoperative third day PMI (P = .031), postoperative third day leukocyte (K/µL) (P = .004), and postoperative seventh day leukocyte (K/µL) (P = .002). There was no meaningful relationship between PMI and early postoperative complications. Conclusion: We think PMI is a more valuable indicator than MPV as an inflammation marker in cardiac surgery. In our opinion, PMI is a cheap and valuable inflammation marker that can be used in coronary surgery that can be obtained from routine hemogram test and can easily be evaluated.

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Association Between New Platelet Indices And Calcific Aortic Stenosis: Plateletcrit And Platelet to Lymphocyte Ratio

Cited by 3 publications

References 19 publications

Can hematologic inflammation markers be the indicator of early pregnancy loss?

Can hematologic inflammation markers be the indicator of early pregnancy loss?

The Role of Platelet Indices in Predicting Short-Term Mortality in Elderly Patients with Pulmonary Embolism

Comparison of Platelet Mass Index in On-Pump and Off-Pump Coronary Artery Bypass Surgery

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