Association Between Single Nucleotide Polymorphisms (SNPs) in the Promoter of Adiponectin Gene, Hypoadiponectinemia, and Diabetes

Sheng, Tianxin; Lu, Yunhe; Yang, Kunlong; Jin, Yan; Wu, Yinghua; Zhang, Zibo; Jin, Yanhua; Jin, Xin

doi:10.5958/2349-2988.2016.00004.8

Cited by 5 publications

(1 citation statement)

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“…As a result, the rpoB and matK In/Dels and SNPs that were acquired might be used as a qualitative molecular marker for species authentication. [20][21][22][23][24] Figure 2: DNA amplification profile of different loci.…”

Section: Detection Of Snps and In/delsmentioning

confidence: 99%

Authentication of Averrhoa carambola L. Using DNA Barcoding: Detection of SNPs and Evaluation of Phylogenetic Relationship

Giri¹,

Biswal²,

Jena³

et al. 2023

Ind. J. Pharm. Edu. Res

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Background: Averrhoa carambola L. (star fruit) is an underutilized plant in the family Oxalidaceae. The plant has various pharmacological activities and has fleshy juicy fruit with high nutritional value and is rich in vitamins. Objectives: This study aims to authenticate and examine the evolutionary relationships between various Averrhoa taxa. Materials and Methods: The species identification was verified using the well-established DNA barcoding method. For this, a few predetermined loci including rpoB, matK, atpF-atpH, and rbcL were employed. Results: Amplicons were observed with a molecular weight of 450bp, 950bp, 800bp, and 650bp respectively as reported earlier. The sequences of these loci were submitted to NCBI. The sequences were approved with accession numbers MN447319, MN733917, MT195537, and MT195538 respectively. The amplified loci of the species and related taxa of the genus were compared using bioinformatics tools. 204 numbers of SNPs/indels were identified out of which some are unique for the species. K2P analysis showed that the maximum intraspecific distance (1.3%) was lower than the minimum interspecific distance (2.6%). Conclusion: Among the different universal barcoding loci, matK was found to be most informative in terms of the occurrence of SNPs and genetic distance. So, the information can be utilized for species authentication in the family Oxalidaceae.

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Section: Detection Of Snps and In/delsmentioning

confidence: 99%

Authentication of Averrhoa carambola L. Using DNA Barcoding: Detection of SNPs and Evaluation of Phylogenetic Relationship

Giri¹,

Biswal²,

Jena³

et al. 2023

Ind. J. Pharm. Edu. Res

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Detection of SNPs in Merremia and its related taxa for species identification using DNA barcode markers

Satapathy

Mohanta

Jena

et al. 2022

RJPT

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Merremiae is one of the least defined tribes in the family Convolvulaceae. It contains number of species which are basically herbs and shrubs. Species identification is a tedious work in the tribe using morphological characters as these traits are often influenced by environmental factors. In the present piece of work, we have analysed five taxa (Merremia umbellata, Merremia vitifolia, Merremia tridentata (Pubescens) and Merremia tridentata (Alatipes) along with one species of Ipomoea - Ipomoea calycina) with help of DNA barcode marker. We have used seven DNA barcoding regions from organellar DNA. Clear and reproducible amplifications were obtained in most of the cases but we failed to observe remarkable variation in amplified fragment size. Variations were detected in the DNA sequence associated with matK and rbcL loci. Sequence analysis showed visible difference between the intra and inter specific genetic distance based on K2P model for both the loci. From the sequenced data we found unique SNPs and In/Dels for the different taxa included in the study. Based upon the matK and rbcL SNP variance table, two dendrograms were constructed and authentication of species of Merremia and its relative were carried out. This work will help in authentic identification of the different taxa in the tribe Merremiae.

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Compendious Review on Adipokines of Corpulence

Hashim

2022

RJPT

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Adipokines are biologically effective substances released by adipose tissue and contributed for the management of many biological processes such as food intake, energy spending, adipocyte growing, tissue susceptibility to insulin, function of endothelium and many others. The modes of action of adipokines are autocrine or paracrine in adipocyte and endocrine in other tissues such as muscles, liver, and brain. Therefore, abnormal actions or levels of many adipokines may act as vinculum between corpulence, or cellular injury, and insusceptibility to insulin. Hereafter, the guidelines for the treatment of corpulence and related metabolic disorders may focus on the uses of drugs with adipokines agonist or antagonist properties, long acting, and less adverse effects.

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Association Between Single Nucleotide Polymorphisms (SNPs) in the Promoter of Adiponectin Gene, Hypoadiponectinemia, and Diabetes

Cited by 5 publications

References 0 publications

Authentication of Averrhoa carambola L. Using DNA Barcoding: Detection of SNPs and Evaluation of Phylogenetic Relationship

Authentication of Averrhoa carambola L. Using DNA Barcoding: Detection of SNPs and Evaluation of Phylogenetic Relationship

Detection of SNPs in Merremia and its related taxa for species identification using DNA barcode markers

Compendious Review on Adipokines of Corpulence

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