Association of facial hemangiomas with Dandy-Walker and other posterior fossa malformations

Familial Segregation of Hemangiomas and Vascular Malformations as an Autosomal Dominant Trait

“…The family pedigrees are shown in the Figure. syndrome). [7][8][9][10][11] In contrast to several heritable vascular malformation syndromes (eg, hereditary hemorrhagic telangiectasia, cerebral vascular malformations, and mucocutaneous venous vascular malformations), syndromes associated with hemangiomas do not appear to be inherited. Interestingly, Gorlin et al 12 observed a marked female predilection in syndromes associated with facial hemangiomas that far exceeded the expected 3:1 to 4:1 female-male ratio.…”

Hemangiomas of Infancy

“…Although we did not look for them systematically, large mediastinal hemangiomas were found in 3 patients, a finding that has been reported in several previous cases. [22][23][24] With improved imaging techniques, we may discover that this occurrence is more common than previously realized. Although not observed in our series, large facial hemangiomas have also been associated with extensive gastrointestinal tract involvement.…”

Association of Solitary, Segmental Hemangiomas of the Skin With Visceral Hemangiomatosis

“…We found only 1 case with a hemangioma morphology similar to that described in case 1-specifically, with multiple small facial hemangiomas in a segmental distribution. 13 Thirty (64%) of the total of 47 cases described only 1 extracutaneous site of visceral hemangioma; 11 patients (23%) had 2 and 6 patients (13%) had 3 or more sites involved. The liver was the most common extracu- taneous site, followed by the gastrointestinal tract, brain, mediastinum, and lung.…”