Association of Lifestyle-Related Comorbidities With Periodontitis

Lee, Jae Hong; Lee, Jung Seok; Park, Jin Young; Choi, Jung Kyu; Kim, Dong Wook; Kim, Young Taek; Choi, Seong Ho

doi:10.1097/md.0000000000001567

Cited by 77 publications

(99 citation statements)

References 40 publications

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“…These results are consistent with those of Lee et al [11], who conducted a similar analysis, adjusting for sociodemographic factors and lifestyle-related comorbidities.…”

Section: Discussionsupporting

confidence: 82%

Association between periodontal flap surgery for periodontitis and vasculogenic erectile dysfunction in Koreans

Lee

Choi

Kim

et al. 2017

J Periodontal Implant Sci

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medical checkup data from 2002 to 2013 were used to evaluate the association between periodontal surgery for the treatment of periodontitis (PSTP) and vasculogenic erectile dysfunction (VED). Methods: Bivariate and multivariate logistic regression analyses were applied to a longitudinal retrospective database to assess the association between PSTP and VED while adjusting for the potential confounding effects of sociodemographic factors (age, household income, insurance status, health status, residence area, and smoking status) and comorbidities (diabetes mellitus, angina pectoris, cerebral infarction, and myocardial infarction). Results: Among the 7,148 PSTP within the 268,296 recruited subjects, the overall prevalence of VED in PSTP was 1.43% (n=102). The bivariate analysis showed that VED was significantly related to PSTP (odds ratio [OR], 1.99; 95% confidence interval [CI], 1.38-2.06; P<0.001), and this was confirmed in the multivariate analysis after adjusting for sociodemographic factors and comorbidities (OR, 1.29; 95% CI, P=0.002). Conclusions: Subjects with a history of periodontal flap surgery had a significantly higher risk of VED, after adjusting for potential confounding factors. Further studies are required to identify the key mechanisms underlying the association between severe periodontal disease and VED.

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“…These results are consistent with those of Lee et al [11], who conducted a similar analysis, adjusting for sociodemographic factors and lifestyle-related comorbidities.…”

Section: Discussionsupporting

confidence: 82%

Association between periodontal flap surgery for periodontitis and vasculogenic erectile dysfunction in Koreans

Lee

Choi

Kim

et al. 2017

J Periodontal Implant Sci

Self Cite

View full text Add to dashboard Cite

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“…In the second step of evaluation, 18 more articles were excluded, which were reviews, commentaries, letters to the editor, experimental models, and/or did not answer the focused question (see the appendix). In total nine studies Keller et al, 2012;J. H. Lee et al, 2015;Matsumoto et al, 2014;Oguz et al, 2013;Sharma et al, 2011;Tsao et al, 2015;Uppal et al, 2014;Zadik et al, 2009) were included in the present systematic review and processed for data extraction.…”

Section: Study Selection and Characteristicsmentioning

confidence: 99%

“…These primary studies Keller et al, 2012; J. H. Lee et al, 2015;Matsumoto et al, 2014;Oguz et al, 2013;Sharma et al, 2011;Tsao et al, 2015;Uppal et al, 2014;Zadik et al, 2009) were conducted in the following countries: India, Israel, Japan, Korea, Taiwan, and Turkey. Seven studies (Keller et al, 2012;J.…”

Section: Study Selection and Characteristicsmentioning

confidence: 99%

“…All studies Keller et al, 2012; J. H. Lee et al, 2015;Matsumoto et al, 2014;Oguz et al, 2013;Sharma et al, 2011;Tsao et al, 2015;Uppal et al, 2014;Zadik et al, 2009) were performed on humans and under health care or university settings. These primary studies Keller et al, 2012; J. H. Lee et al, 2015;Matsumoto et al, 2014;Oguz et al, 2013;Sharma et al, 2011;Tsao et al, 2015;Uppal et al, 2014;Zadik et al, 2009) were conducted in the following countries: India, Israel, Japan, Korea, Taiwan, and Turkey.…”

Section: Study Selection and Characteristicsmentioning

confidence: 99%

“…These include increasing age, poorly controlled diabetes mellitus (DM), hyperlipidemia, lower urinary tract symptoms, hypertension, psychological stress, and low physical activity (Ponholzer et al, 2005). A limited number of studies Keller, Chung, & Lin, 2012; J. H. Lee et al, 2015;Matsumoto et al, 2014;Oguz et al, 2013;Sharma, Pradeep, & Raju, 2011;Tsao et al, 2015;Uppal, Bhandari, & Singh, 2014;Zadik, Bechor, Galor, Justo, & Heruti, 2009) have identified an association between ED and chronic periodontitis (CP), a disease of the supporting structures of teeth, namely cementum, gingiva, periodontal ligament, and alveolar bone. In the study by Matsumoto et al (2014), an information sheet was distributed to 300 adult men with ED that received a comprehensive dental examination.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Association Between Periodontal Disease and Erectile Dysfunction: A Systematic Review

Kellesarian

Malignaggi

et al. 2016

Am J Mens Health

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A limited number of studies have reported an association between erectile dysfunction (ED) and chronic periodontitis (CP). The aim of the present study is to assess the association between CP and ED through a systematic review of published literature. To address the focused question, "Is there a relationship between ED and CP?" indexed databases were searched till December 2015 using various key words "erectile dysfunction," "periodontal disease," "periodontitis," "dental infection," and "impotence." Letters to the editor, commentaries, historic reviews, and experimental studies were excluded. The pattern of the present systematic review was customized to primarily summarize the pertinent data. Nine studies were included. Seven studies had a cross-sectional design and two studies were randomized control trials. The number of study participants ranged between 53 and 513,258 individuals with age ranging between 20 years and 85 years (median age ranging between 34.9 ± 4.9 years and 50.9 ± 16.6 years). In all studies, a positive relationship between CP and ED was reported. In four studies, odds ratio were reported, ranging between 1.53 and 3.35. From the literature reviewed, there seems to be a positive association between ED and CP; however, further well-designed controlled clinical trials are needed in this regard. It is emphasized that physicians should refer patients with ED to oral health care providers for a comprehensive oral evaluation and treatment.

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Association between chronic diseases and severe periodontal disease progression: A retrospective cohort study in a city of Japan

Nin,

Sun,

Maeno

et al. 2024

J of Gen and Family Med

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BackgroundChronic periodontal disease primarily causes tooth loss and oral frailty and is linked to chronic conditions such as diabetes mellitus. However, its progression and broader studies on chronic diseases have not been well explored. This study aimed to investigate this association using claims data.MethodsThis retrospective cohort study used linked medical, dental, and pharmacy claims data from a local municipality in Japan. The study included participants aged 40–70 years who had received medical care between April 2017 and March 2018. Exposures included age, sex, and common chronic diseases previously reported to be associated with periodontal diseases (21 diseases). We defined the outcome, “progression of severe periodontitis” as the worsening of periodontal disease to a severe stage requiring surgery or tooth extraction, determined by the presence of a periodontal surgery code or a deeper probing pocket depth (≥6 mm) code along with the tooth extraction procedure code. The participants were followed up until March 2022, and multivariate analysis was conducted using Cox proportional hazard models.ResultsAmong 28,846 participants, 1035 (3.6%) progressed to severe periodontal disease. In the multivariate analysis, only diabetes mellitus was significantly associated with severe periodontal disease, with a hazard ratio of 1.26 (95% confidence interval, 1.08–1.53) among all chronic diseases.ConclusionPatients with diabetes mellitus had a high risk of severe periodontal disease progression, suggesting that proactive dental visits should be recommended to prevent severe periodontal disease.

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Association of Lifestyle-Related Comorbidities With Periodontitis

Cited by 77 publications

References 40 publications

Association between periodontal flap surgery for periodontitis and vasculogenic erectile dysfunction in Koreans

Association between periodontal flap surgery for periodontitis and vasculogenic erectile dysfunction in Koreans

Association Between Periodontal Disease and Erectile Dysfunction: A Systematic Review

Association between chronic diseases and severe periodontal disease progression: A retrospective cohort study in a city of Japan

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