Atrial Fibrillation Developing in the Acute Phase of Myocardial Infarction

Cristal, N; Peterburg, I.; Szwarcberg, J.

doi:10.1378/chest.70.1.8

Cited by 59 publications

(43 citation statements)

References 16 publications

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“…A variant ventricular rate followed by irregular ventricular filling and reduced cardiac output that resulted from a lost contribution of atrial click have been proposed as the mechanisms of hemodynamic deterioration. 5) As compared with AMI patients with normal sinus rhythm, AMI patients with new-onset AF have been shown to have worse baseline characteristics, more complicated hospital courses, and unfavorable clinical outcomes such as higher incidences of advanced congestive heart failure (CHF), cardiac embolic stroke, and mortality. 1,[6][7][8][9][10]) Surprisingly, all of these studies were conducted in the prethrombolytic or thrombolytic eras.…”

Section: T He Incidence Of New-onset Atrial Fibrillation (Af) Is Re-mentioning

confidence: 99%

The Prognostic Value of Atrial Fibrillation on 30-Day Clinical Outcome in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

et al. 2011

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SummaryThis study evaluated the association between atrial fibrillation (AF) and 30-day clinical outcome in patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Between January 2005 and October 2009, 783 consecutive patients with acute STEMI undergoing primary PCI were enrolled. Of these patients, 85 (10.9%) with AF during admission were categorized into group 1, while the remaining 698 (89.1%) with sinus rhythm during admission served as group 2. The results demonstrated that the incidence of advanced Killip score (defined as ≥ score 3) and advanced congestive heart failure (defined as ≥ NYHA class 3) were significantly higher, whereas the left ventricular ejection fraction (LVEF) was notably lower in group 1 than in group 2 (all P < 0.003). Additionally, the normal blood flow in the infarct-related artery was notably lower in group 1 than in group 2 (P = 0.003). Moreover, the incidences of new-onset stroke and 30-day mortality were remarkably higher in group 1 than in group 2 (all P < 0.003). Furthermore, Kaplan-Meier analysis demonstrated that the 30-day survival rate was markedly lower in AF patients than in those with sinus rhythm. However, multivariate stepwise Cox regression analysis demonstrated that the advanced Killip score and low LVEF were significantly and independently predictive of 30-day mortality (all P < 0.004). In conclusion, AF was significantly associated with 30-day mortality. (Int Heart J 2011; 52: 153-158)

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Section: T He Incidence Of New-onset Atrial Fibrillation (Af) Is Re-mentioning

confidence: 99%

The Prognostic Value of Atrial Fibrillation on 30-Day Clinical Outcome in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

et al. 2011

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“…Some investigators found no increase in mortality related to the presence of AF, [10][11][12][13] while other studies showed a greater overall early mortality rate in patients with anterior myocardial infarction with AF. [14][15] In AMI atrial fibrillation is usually transient and may not require treatment. However, if the arrhythmia causes a rapid ventricular rate with severe hypotension or circulatory collapse, cardio version by an immediate synchronized DC shock should be considered.…”

Section: Introductionmentioning

confidence: 99%

Atrial Fibrillation in Acute Myocardial Infarction

Bhattarai¹,

Sayganov²

2015

Nepalese Heart J.

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“…[1][2][3][4][5][6][7] Little is known concerning the incidence of PAF, the factors associated with its occurrence, and its effects on the short-and long-term prognoses of patients with AMI in the TE. In the present study, we examined a nationwide cohort of patients hospitalized for AMI in Israel during 2 months in 1992, 1994, and 1996 and compared them with patients enrolled during 1981 through 83 in the SPRINT registry.…”

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confidence: 99%

Significance of Paroxysmal Atrial Fibrillation Complicating Acute Myocardial Infarction in the Thrombolytic Era

et al. 1998

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Background-Paroxysmal atrial fibrillation (PAF) is considered a frequent complication of acute myocardial infarction (AMI), associated with increased in-hospital and long-term mortality rates. This notion is based on data collected before thrombolysis and additional modern methods of treatment became widely available, and no information is available on the significance of PAF in the general population with AMI in the thrombolytic era. The aim of the present study was to define the incidence, associated clinical parameters, and short-and long-term prognostic significance of PAF in patients with AMI in the thrombolytic era. Methods and Results-A prospective, nationwide survey was conducted of 2866 consecutive patients admitted with AMI in all 25 coronary care units in Israel during January/February 1992). The data were compared with a previous Israeli study of 5803 patients with AMI hospitalized in 1981 through 1983 (prethrombolytic era [PTE]). Patients in the TE with PAF were older and had a worse risk profile than those without PAF. PAF in the TE was independently associated with increased 30-day (odds ratio, 1.32; 95% confidence interval, 0.92 to 1.87) and 1-year (relative risk, 1.33; 95% confidence interval, 1.05 to 1.68) mortality rates. The incidence of PAF (8.9% and 9.9%) and the 30-day (25.1% and 27.6%) and 1-year (38.4% and 42.5%) mortality rates of patients with PAF were similar in the TE and PTE, although PAF in the TE occurred in older and sicker patients than those in the PTE. After adjustment for conventional risk factors, PAF was associated with significantly lower 30-day (odds ratio, 0.64; 95% confidence interval, 0.44 to 0.94) and 1-year (relative risk, 0.69; 95% confidence interval, 0.54 to 0.88) mortality rates compared with the PTE. Conclusions-Patients with AMI who develop PAF in the TE have significantly worse short-and long-term prognoses than patients without PAF, mostly due to their worse risk profile. After adjustment for confounding factors, patients with PAF in the TE have a better overall outcome than counterparts in the PTE, probably reflecting the better management of patients with AMI in the TE. (Circulation. 1998;97:965-970.)

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Atrial Fibrillation Developing in the Acute Phase of Myocardial Infarction

Cited by 59 publications

References 16 publications

The Prognostic Value of Atrial Fibrillation on 30-Day Clinical Outcome in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

The Prognostic Value of Atrial Fibrillation on 30-Day Clinical Outcome in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Atrial Fibrillation in Acute Myocardial Infarction

Significance of Paroxysmal Atrial Fibrillation Complicating Acute Myocardial Infarction in the Thrombolytic Era

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