2010 20th International Conference on Pattern Recognition 2010
DOI: 10.1109/icpr.2010.370
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Automated Gland Segmentation and Classification for Gleason Grading of Prostate Tissue Images

Abstract: Abstract-The well-known Gleason grading method for an H&E prostatic carcinoma tissue image uses morphological features of histology patterns within a tissue slide to classify it into 5 grades. We have developed an automated gland segmentation and classification method that will be used for automated Gleason grading of a prostatic carcinoma tissue image. We demonstrate the performance of the proposed classification system for a three-class classification problem (benign, grade 3 carcinoma and grade 4 carcinoma)… Show more

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Cited by 54 publications
(38 citation statements)
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“…In reference to the results reported in the literature, it is worthy to note the recent contributions by Doyle et al [57], by Huang et al [61], by Khurd, et al [63], and by Nguyen et al [64]. were shown to have nearly the same energy regardless the shift of the input signal.…”
Section: Discussionmentioning
confidence: 88%
“…In reference to the results reported in the literature, it is worthy to note the recent contributions by Doyle et al [57], by Huang et al [61], by Khurd, et al [63], and by Nguyen et al [64]. were shown to have nearly the same energy regardless the shift of the input signal.…”
Section: Discussionmentioning
confidence: 88%
“…All the experiments are conducted on a 2.8 GHz Intel Core i7 machine with 16GB RAM. [12] 0.43 ± 0.12 0.59 ± 0.12 0.39 ± 0.14 0.52 ± 0.15 Naik et al [13] 0.57 ± 0.14 0.72 ± 0.12 0.43 ± 0.14 0.56 ± 0.14 Nguyen et al [14] 0.52 ± 0.12 0.67 ± 0.12 0.35 ± 0.09 0.46 ± 0.09 TGPM 0.78 ± 0.07 0.87 ± 0.05 0.68 ± 0.12 0.77 ± 0.11 RPM 0.82 ± 0.07 0.90 ± 0.05 0.78 ± 0.10 0.85 ± 0.08 a The result is excerpted from [15]. NA means not available.…”
Section: F Comparative Resultsmentioning
confidence: 99%
“…An evident limitation of the framework is that level sets often lead to erroneous segmentation in cases where lumen appears as a complex texture rather than a relatively smooth region such as healthy and adenomatous colon tissues. Nguyen et al [14] employed the prior knowledge about glandular constituents in order to extract glandular regions. Their algorithm first jointly segments nuclei and cytoplasm to form a rough glandular boundary and then uses a region growing algorithm to expand the luminal area.…”
Section: Related Workmentioning
confidence: 99%
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“…Gland labeling/segmentation, as one subproblem of gland instance segmentation, is a well-studied field where various methods have been explored, such as morphology-based methods [6], [7], [8], [9] and graph-based methods [10], [11]. However, glands must be recognized individually to enable the following morphology analysis.…”
mentioning
confidence: 99%