Introduction: The adoption of innovative methodologies for teacher training in nursing is a challenge and also a necessity. Pedagogical strategies used for the formation of the nurse faculty must meet the demands of health, which are in constant transformation, being this a complex task. In this sense, the Design Thinking is an active innovative methodology which aggregates on teacher training of nurses, awakening empathy, collaborative work, creativity and solving problems inherent in pedagogical practice. Goal: Analyze the contributions of Design Thinking as active innovative methodology in teacher education in nursing. Method: Qualitative, case study, based on the theory of interactionist partner Lev Semionovich Vygotsky. For the production of data, we opted for conducting an educational workshop based on the stages of Design Thinking for educators. 15 teachers participated in training, Master students and doctoral candidates of a graduate degree program in nursing, a Public University located in Curitiba-Paraná. The pedagogical workshop was structured in three phases and seven activities, with total duration of 8 hours. The data were recorded audio and video, in conformity with the ethical aspects. The project was approved by the Committee of ethics in research with human beings, under the opinion n°2.607.086. Results: In order to meet the requirements of the Design Thinking, the researcher assumed the role of mediator and designer thinker project leader, whereas participants of designer's thinkers. In the first step of two dynamic workshop were applied with the aim of bringing the participants to the concepts of empathy and collaborative work; After setting three groups and the strategic challenge "How do we assess student learning?" Was exposed, which served as the guiding principle for all the steps and subsequent activities. In addition, rescue strategies have been implemented to previous knowledge, exploratory research and elaboration of maps of empathy and personas. In the second step, the most viable, desirable and feasible were defined for that, so they were prototype. In the third step, the prototypes presented were named as "Multiple assessment Cases", "Trajeção" and "learning assessment tool". Complementary to the process, an assessment tool with open and closed questions was applied in order to obtain feedback about strategies and resources used. Conclusions: From the perspective of the theoretical, Design Thinking showed up as an active methodology which is worth of various elements mediators working in the zone of Proximal Development of participants, for example the map of empathy and persona. Through the collaborative work and social interaction, provides teacher training, as well as encourages creativity by providing for the development of prototypes. The Design Thinking contributed to the teacher training of the participants as the theme "assessment of learning" was problematic, there was sharing of knowledge, experiences and collective search for solving a problem in a creative and innovati...