2012
DOI: 10.1186/alzrt125
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Ayurvedic medicinal plants for Alzheimer's disease: a review

Abstract: Alzheimer's disease is an age-associated, irreversible, progressive neurodegenerative disease that is characterized by severe memory loss, unusual behavior, personality changes, and a decline in cognitive function. No cure for Alzheimer's exists, and the drugs currently available to treat the disease have limited effectiveness. It is believed that therapeutic intervention that could postpone the onset or progression of Alzheimer's disease would dramatically reduce the number of cases in the next 50 years. Ayur… Show more

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Cited by 154 publications
(111 citation statements)
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“…[22][23][24] Plant based compounds have been used as cognition enhancers herbs like Withania somnifera, Centella asiatica, Curcuma longa, Bacopa monnieri, Convolvulus pluricaulis, Celastrus paniculatus, Nardostachys jatamansi have been reported to be used in management of cognitive impairment in Ayurvedic system of medicine. 25,26 Acetyl cholinesterase inhibitory activity is dose dependently increasing at a concentration ranging from 50 µg/ml to 300 µg/ml and when compared to standard Galanthamine the inhibitory activity is moderate even though the tested extract shows significant activity. The results are depicted in Table 1 and Figure 1 and can be used for treating neurodegenerative disorders.…”
Section: Resultsmentioning
confidence: 99%
“…[22][23][24] Plant based compounds have been used as cognition enhancers herbs like Withania somnifera, Centella asiatica, Curcuma longa, Bacopa monnieri, Convolvulus pluricaulis, Celastrus paniculatus, Nardostachys jatamansi have been reported to be used in management of cognitive impairment in Ayurvedic system of medicine. 25,26 Acetyl cholinesterase inhibitory activity is dose dependently increasing at a concentration ranging from 50 µg/ml to 300 µg/ml and when compared to standard Galanthamine the inhibitory activity is moderate even though the tested extract shows significant activity. The results are depicted in Table 1 and Figure 1 and can be used for treating neurodegenerative disorders.…”
Section: Resultsmentioning
confidence: 99%
“…Massage was found to reduce the level of stress related Serum Cortisol, arginine vasopressin and salivary stress protein chromogranin A with concomitant increase in circulating lymphocytes and cerebral blood flow. 26,27,28,29,30 All these procedures also influence hormonal and cerebral blood flow levels. 31,32,33,34 These all factors may lead to improve the cerebral function, enhance the alertness and concentration abilities especially the Shirodhara, the relaxing and anxiolytic actions for which are well established.…”
Section: Managementmentioning
confidence: 99%
“…1 2, 2-diphenyl-1-picrylhydrazyl radical (DPPH) free radical scavenging assay 2, 2-diphenyl-1-picrylhydrazyl radical (DPPH) is a dark-coloured crystalline powder composed of stable free-radical molecules. DPPH has major application in laboratory research most notably in antioxidant assays.…”
Section: Phytochemical Screeningmentioning
confidence: 99%
“…Indeed, several scientific studies have described the use of various medicinal plants and their constituents for treatment of diseases. Plants have shown the presence of many valuable compounds, such as lignans, flavonoids, tannins, polyphenols, triterpenes, sterols, and alkaloids, that show a wide spectrum of pharmacological activities, including anti-inflammatory, anti-amyloidogenic, anti-cholinesterase, hypolipidemic, and antioxidant effects [1]. Considerable research on pharmacognosy, phytochemistry, pharmacology and clinical therapeutics has been carried out on ayurvedic medicinal plants.…”
mentioning
confidence: 99%