Azithromycin vs doxycycline in the treatment of inclusion conjunctivitis

Conjunctivitis

“…1 Conjunctival hyperemia, mucopurulent discharge, and lymphoid follicle formation 51 are hallmarks of this condition. Discharge is often purulent or mucopurulent.…”

Effect of oral azithromycin in the treatment of chlamydial conjunctivitis

“…The review of the medical records revealed that the bacteriological eradication rate was high after the first 2-week course of oral azithromycin treatment (70.4%, 95% CI, 53.2-87.6), but not as high as reported elsewhere. 11,15 For example, Katusic et al 11 reported a C. trachomatis eradication rate as high as 92% with only a single dose of oral azithromycin. They evaluated the eradication rate of C. trachomatis 10-12 days after the initial treatment, which was 2-3 weeks earlier than in our study.…”

“…[6][7][8][9] The World Health Organization now also advocates the use of oral azithromycin in the 'SAFE' strategy as an antibiotic for the control of trachoma worldwide. 10 For C. trachomatis-induced inclusion conjunctivitis, 11 because of its high prevalence and association with genital tract infection, systemic treatment with oral antibiotics is preferred. 12 Because azithromycin, an antibiotic, is intracellularly active and exhibits excellent activity against C. trachomatis in vitro, 13 it is now also used for the treatment of C. trachomatis-induced inclusion conjunctivitis and even neonatal conjunctivitis.…”

“…12 Because azithromycin, an antibiotic, is intracellularly active and exhibits excellent activity against C. trachomatis in vitro, 13 it is now also used for the treatment of C. trachomatis-induced inclusion conjunctivitis and even neonatal conjunctivitis. 11,14 The efficacy of oral azithromycin has already been shown in the treatment of both trachoma [6][7][8][9] and adult inclusion conjunctivitis 11,15 in many studies. Although Taiwan was once an endemic area for trachoma in the 1950s and 1960s, 16,17 the prevalence of trachoma in children had decreased to 15% in 1995.…”

Lėtinis Chlamidinis Konjunktyvitas: Atvejo Pristatymas

“…Pirmo pasirinkimo vaistai yra azitromicinas 1 g vienkartinai arba doksiciklinas 100 mg 2 k/d 1-3 savaites [12,13]. Nustatyta, kad vienkartinė azitromicino 1 g dozė efektu prilygsta doksiciklino 10 dienų kursui [14]. Vis dėlto kartais vienkartinės azitromicino dozės nepakanka.…”