2003
DOI: 10.1046/j.1365-2559.2003.01651.x
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Basal cell adenocarcinoma in minor salivary glands

Abstract: Basal cell adenocarcinoma is a rare and relatively recently characterized malignant salivary gland tumour, the malignant counterpart of basal cell adenoma. Diagnosis depends on finding features similar to adenoma but with an infiltrative growth pattern and exclusion of adenoid cystic carcinoma, sialoblastoma and basaloid squamous carcinoma. Basal cell adenocarcinoma is very rarely reported in minor salivary glands. We report three cases of basal cell adenocarcinoma affecting the labial, buccal and palatal mino… Show more

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Cited by 49 publications
(32 citation statements)
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“…[1,2,5,6] True invasion must be distinguished from both multinodularity with a pushing type of growth pattern and a multifocal origin in adjacent salivary lobules, both of which are features of basal cell adenoma. [9] Histological picture of our case showed a presence of a cytological atypia and infiltrative growth pattern although there was no evident vascular or perineural invasion.…”
Section: Discussionmentioning
confidence: 47%
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“…[1,2,5,6] True invasion must be distinguished from both multinodularity with a pushing type of growth pattern and a multifocal origin in adjacent salivary lobules, both of which are features of basal cell adenoma. [9] Histological picture of our case showed a presence of a cytological atypia and infiltrative growth pattern although there was no evident vascular or perineural invasion.…”
Section: Discussionmentioning
confidence: 47%
“…[8] The involvement of the minor salivary glands is very rare, and only few cases have been reported involving the palate, buccal mucosa, labial mucosa, and the submandibular gland. [9] BCACs typically arise in adults above 60 years and have no gender predilection. [5,10] However, according to Nagao et al, there is an age range of 42-81 years (mean 59.2 years).…”
Section: Discussionmentioning
confidence: 99%
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“…In major salivary glands, removal of the whole gland is recommended, and follow-up radiotherapy after wide excision has been proposed for lesions with perineural or perivascular invasion [7,8]. In this case, even though there was no suspicious metastatic lymph node and the histological grades were low and intermediate, adjuvant radiotherapy was administered to the patient because the tumor cells were positive on the resection margin that was attached to the parapharyngeal fat tissue, and perineural invasion in the deep lobe tumor was reported.…”
Section: Discussionmentioning
confidence: 99%
“…In addition, there is no agreement on the role of radiotherapy. However, postoperative radiotherapy is recommended in the case of surgeries with positive surgical margins or surgical excision of recurrent tumors (21,22) .…”
mentioning
confidence: 99%