Basal cell carcinoma, oculo-cutaneous albinism and actinic keratosis in a native Indian

Chatterjee, Kingshuk; Rasool, Farhan; Chaudhuri, Anita; Chatterjee, Gautam; Sehgal, Virendra; Singh, Neelam

doi:10.4103/0019-5154.117308

Cited by 4 publications

(5 citation statements)

References 10 publications

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“…Basal cell carcinoma in albino skin is rarely reported in the Indian subcontinent and we could trace only one case report from India upon literature survey. [4] However, a study by Kiprono et al . revealed almost identical proportion of squamous cell carcinomas and basal cell carcinomas in African albinos.…”

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confidence: 99%

Multiple basal cell carcinomas in a patient of oculocutaneous albinism

Behera

Tripathy

Kar

2017

Indian Dermatol Online J

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confidence: 99%

Multiple basal cell carcinomas in a patient of oculocutaneous albinism

Behera

Tripathy

Kar

2017

Indian Dermatol Online J

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“…Underlying OCA is not known to alter the management of skin malignancies. This is evident from various case reports where nonmetastatic skin tumors were managed with wide local excision in patients with albinism [ 9 , 11 ]. Hence, each individual lesion was excised and submitted for histological assessment.…”

Section: Discussionmentioning

confidence: 99%

“…There are few case reports that have described the synchronous occurrence of more than one type of skin malignancy or premalignant lesion in individuals with OCA. Chatterjee et al reported the case of an Indian albino who presented with concurrent BCC and actinic keratosis, a precursor of SCC [ 9 ]. A prospective study by van der Westhuizen et al described 16 OCA patients with melanocytic or pigmented skin lesions.…”

Section: Discussionmentioning

confidence: 99%

Synchronous Triple Malignancies in an Indian Albino: A Case Report

Darlington

Narayanan

Anitha³

2018

Cureus

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Oculocutaneous albinism (OCA) is a heterogenous disorder of skin pigmentation characterized by hypopigmentation of the skin, hair, and eyes. The absence of melanin predisposes these individuals to ultraviolet rays induced malignancies. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in OCA have been rarely reported. Malignant melanoma (MM) of the skin is also very rarely reported. Synchronous BCC, SCC, and MM are exceedingly rare. We report one such case managed successfully with surgical treatment. All the three malignancies were localized cancers and hence the outcome was good. The importance of regular follow up and periodic self-examination in such predisposed individuals are highlighted.

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“…Concurrent diagnoses reported in the articles included SCC ( n = 22), malignant melanoma ( n = 9), AK ( n = 5), actinic damage ( n = 5), and one each of actinic chelitis, epidermoid carcinoma, and Merkel cell carcinoma (where n is number of articles) (Table 2). 2–8,11–39 …”

Section: Discussionmentioning

confidence: 99%

Identifying and characterizing basal cell carcinomas in persons with albinism

2020

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Background Historically, persons with albinism (PWA) were thought to develop squamous cell carcinoma (SCC) more frequently than basal cell carcinoma (BCC). Recent evidence suggests BCCs in PWA are more common than initially hypothesized. Objective To characterize the presentation of BCC in PWA. Methods Fifty‐four PWA with lesions suspicious for non‐melanoma skin cancer sought care at Tanzanian dermatologic clinics from 2017 to 2019. Demographic and clinical presentation data were recorded. Histologic analysis of each sample was completed. Results The majority of PWA were female (53.7%), with a mean age of 34.6 ± 14.9 years and a mean duration of disease of 0.70 ± 0.73 years. Physician description of histologically proven BCC included ulceration (41.7%), erythema (16.7%), and scale (16.7%). Lesions were most commonly located on the trunk (47.1%) and face (41.2%). Histologic analysis demonstrated 30.2% of lesions were BCC, 26.4% SCC, and 17% Bowen's disease. Limitations Patient population was limited to those visiting clinics, and data were limited by accuracy of the medical record. Conclusions Basal cell carcinoma occurs at a higher rate than SCC in our population, suggesting BCC in PWA is underdiagnosed. It is important to recognize BCC early in PWA to avoid large disease burden and high rates of morbidity and mortality.

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Basal cell carcinoma, oculo-cutaneous albinism and actinic keratosis in a native Indian

Cited by 4 publications

References 10 publications

Multiple basal cell carcinomas in a patient of oculocutaneous albinism

Multiple basal cell carcinomas in a patient of oculocutaneous albinism

Synchronous Triple Malignancies in an Indian Albino: A Case Report

Identifying and characterizing basal cell carcinomas in persons with albinism

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