Base-Free Suzuki–Miyaura Coupling Reaction Using Palladium(II) Supported Catalyst in Water

Boehmite@SiO2@ Tris (hydroxymethyl)aminomethane‐Cu(I): a novel, highly efficient and reusable nanocatalyst for the C‐C bond formation and the synthesis of 5‐substituted 1H‐tetrazoles in green media

“…[2][3][4] The C-C bond formations are the most important synthetic transformations in industry and in current researches. [5,6] These types of reactions are of important in the preparation of natural products, [7] drugs and pharmaceutical compounds, [8] polymers, [2,9] herbicides [3] and industrially important starting materials. [6] In order to understand the importance of C-C coupling reactions, it should be noted that, in 2010, the Nobel Prize for Chemistry was awarded to Suzuki, Negishi and Heck for their ground breaking contributions on Pd-catalyzed cross-coupling reactions in the organic synthesis.…”

Hydrophilic Pd/MgO Nanosystem for the Highly Efficient Aqueous-Phase Catalysis of Suzuki–Miyaura Reactions

“…This observation was accorded with the reactions that were performed in organic solvents. 33,40,50 However, when the substituted group (electron-donating or -withdrawing) was introduced on aryl bromide, the yield was relatively decreased, which might be caused by the low solubility of the substrate in the aqueous system. For comparison, it could be seen that when (Pd/MgO) bulk was used, the yield of the reaction was relatively poor compared to that of (Pd/MgO) nano , which could be attributed to the highly dispersed and much smaller Pd NPs compared to (Pd/ MgO) bulk .…”

“…Palladium-catalyzed Suzuki coupling reaction has become one of the most effective and important methods for making C–C bonds since the first report in 1979. − The coupling reaction of aryl halides with organoboron reagents that features extensive substrate applicability and functional group tolerance has been widely applied in the synthesis of versatile natural products, pharmaceuticals, and functional materials. − Currently, homogeneous palladium-based catalysts, such as palladium salts with phosphine ligands or N -heterocyclic carbene ligands, have still been the most widely used catalysts, and products with desirable yields and efficiencies have been achieved. − Nevertheless, they suffer from intrinsic deficiency in product separation and catalyst recycling, which significantly restricted their large-scale industrial application. Besides, most Suzuki coupling reactions have been currently performed in large amounts of organic solvents ( N , N -dimethylformamide (DMF), tetrahydrofuran (THF), 1,4-dixoane, and so forth), which are toxic and harmful to the environment. − Therefore, out of academic and industrial research, a heterogeneous supported palladium catalyst that exhibits high catalytic activities and is easy to recycle when operated in green solvents, particularly in water, to realize green and efficient synthesis is urgently needed.…”

Hydrotalcite‐Supported Ceria Nanoparticles as a Heterogeneous Catalyst for One‐Pot Synthesis of Imines under Atmospheric Air

“…[20][21][22] Recently, we have synthesized various cerium-based catalysts with their application in organic reactions like-oxidation of benzyl alcohols, imines formation etc. [23][24][25] Herein, we have synthesized ceria supported hydrotalcite catalyst, used in oxidation of benzyl alcohol and direct imines formation under different reaction conditions. Table 1 represents the investigation of preparation of CeO 2 /HT using the different solvents and their application observed by the selective oxidation of 2-nitrobenzyl alcohol in toluene using air as an oxidant.…”