Baseline correction method for dynamic pressure gradient modulated comprehensive two-dimensional gas chromatography with flame ionization detection

Mikaliunaite, Lina; Sudol, Paige E.; Cain, Caitlin N.; Synovec, Robert E.

doi:10.1016/j.chroma.2021.462358

Cited by 4 publications

(5 citation statements)

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“…One example of a recent development of a tailored baseline correction method is that of Mikaliunaite et al. The authors designed their strategy to accommodate the significant baseline disturbance encountered in dynamic‐pressure‐gradient (flow) modulation [153].…”

Section: Discussionmentioning

confidence: 99%

“…In Figure 3 [153], an example of the workflow is presented. The pressure oscillation is clearly visible in the chromatograms of both samples and blanks (Figure 3A and B).…”

Section: Discussionmentioning

confidence: 99%

“…Panel A shows a sample chromatogram, B represents a background chromatogram, which is subtracted from the signal in panel A; it is the result is presented in C. After smoothning using a Savitzky‐Golay filter, the signal shown in D is obtained. Panel E displays the employed normalization metric to determine the optimal normalization factor, resulting in the signal shown in panel F. Reproduced from [153] with permission.…”

Section: Discussionmentioning

confidence: 99%

“…Baseline-correction models can be mainly categorized into two groups, that is, parametric and nonparametric [149,151]. Parametric approaches fit a polynomial to the baseline and subtract its contribution from the raw data [152,153], therefore, assuming that the baseline is of a certain (predefined) form that can be captured by the employed baseline model [154] Nonparametric approaches are not based on assumptions prior to (typically) applying multivariate resolution methods [149,151].…”

Section: Signal Preprocessing: the Need For A Common Datasetmentioning

confidence: 99%

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Comprehensive two‐dimensional gas chromatography— A discussion on recent innovations

Milani,

van Gilst,

Pirok

et al. 2023

J of Separation Science

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Although comprehensive 2‐D GC is an established and often applied analytical method, the field is still highly dynamic thanks to a remarkable number of innovations. In this review, we discuss a number of recent developments in comprehensive 2‐D GC technology. A variety of modulation methods are still being actively investigated and many exciting improvements are discussed in this review. We also review interesting developments in detection methods, retention modeling, and data analysis.

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Section: Discussionmentioning

confidence: 99%

“…In Figure 3 [153], an example of the workflow is presented. The pressure oscillation is clearly visible in the chromatograms of both samples and blanks (Figure 3A and B).…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Signal Preprocessing: the Need For A Common Datasetmentioning

confidence: 99%

See 2 more Smart Citations

Comprehensive two‐dimensional gas chromatography— A discussion on recent innovations

Milani,

van Gilst,

Pirok

et al. 2023

J of Separation Science

View full text Add to dashboard Cite

show abstract

“…Savitzky-Golay Using a polynomial fit of m th order to (2n + 1) neighboring points (inclusive of the point to be smoothed) with n ≥ m [15] Asymmetric least squares Using a smoother with deviations asymmetrically weighted to estimate a baseline [16] Polynomial fitting Using a polynomial of n th order that is a best fit (in a least-squares sense) for the data [17] Penalized least squares…”

Section: Baseline Correctionmentioning

confidence: 99%